(19 nodes) Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway network (Sordaria macrospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAC_03471	WGS project CABT00000000 data, contig 2.10. (721 aa)
	SMAC_08750	WGS project CABT00000000 data, contig 2.64; Belongs to the peptidase C19 family. (989 aa)
	SMAC_07467	WGS project CABT00000000 data, contig 2.46. (545 aa)
	SMAC_07179	WGS project CABT00000000 data, contig 2.40. (248 aa)
	SMAC_06414	WGS project CABT00000000 data, contig 2.35. (653 aa)
	SMAC_06323	WGS project CABT00000000 data, contig 2.34. (234 aa)
	SMAC_06189	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (722 aa)
	SMAC_06117	E3 ubiquitin-protein ligase. (819 aa)
	SMAC_08991	WGS project CABT00000000 data, contig 2.31. (581 aa)
	SMAC_04722	WGS project CABT00000000 data, contig 2.21. (641 aa)
	SMAC_02119	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (274 aa)
	SMAC_03977	WGS project CABT00000000 data, contig 2.17. (226 aa)
	SMAC_02591	WGS project CABT00000000 data, contig 2.11. (952 aa)
	SMAC_02543	WGS project CABT00000000 data, contig 2.11. (504 aa)
	SMAC_04962	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (237 aa)
	SMAC_01872	WGS project CABT00000000 data, contig 2.5. (227 aa)
	SMAC_06724	WGS project CABT00000000 data, contig 2.3. (217 aa)
	SMAC_02473	WGS project CABT00000000 data, contig 2.3. (235 aa)
	SMAC_01063	WGS project CABT00000000 data, contig 2.2. (901 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMAC_01063	SMAC_02543	F7VNW0	F7VWS3	WGS project CABT00000000 data, contig 2.2.	WGS project CABT00000000 data, contig 2.11.	0.478
SMAC_01872	SMAC_02119	F7VS39	F7W110	WGS project CABT00000000 data, contig 2.5.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.923
SMAC_01872	SMAC_02473	F7VS39	F7VPP1	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.3.	0.998
SMAC_01872	SMAC_03471	F7VS39	F7VW93	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.10.	0.505
SMAC_01872	SMAC_03977	F7VS39	F7W0H4	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.17.	0.998
SMAC_01872	SMAC_04722	F7VS39	F7W290	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.21.	0.912
SMAC_01872	SMAC_04962	F7VS39	F7VUK7	WGS project CABT00000000 data, contig 2.5.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.896
SMAC_01872	SMAC_06189	F7VS39	F7W6A8	WGS project CABT00000000 data, contig 2.5.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.977
SMAC_01872	SMAC_06323	F7VS39	F7W6G6	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.34.	0.911
SMAC_01872	SMAC_06724	F7VS39	F7VPU4	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.3.	0.992
SMAC_01872	SMAC_07467	F7VS39	F7W8P5	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.46.	0.774
SMAC_01872	SMAC_08991	F7VS39	F7W5S4	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.31.	0.878
SMAC_02119	SMAC_01872	F7W110	F7VS39	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	WGS project CABT00000000 data, contig 2.5.	0.923
SMAC_02119	SMAC_02473	F7W110	F7VPP1	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	WGS project CABT00000000 data, contig 2.3.	0.896
SMAC_02119	SMAC_03471	F7W110	F7VW93	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	WGS project CABT00000000 data, contig 2.10.	0.791
SMAC_02119	SMAC_03977	F7W110	F7W0H4	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	WGS project CABT00000000 data, contig 2.17.	0.962
SMAC_02119	SMAC_04722	F7W110	F7W290	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	WGS project CABT00000000 data, contig 2.21.	0.999
SMAC_02119	SMAC_04962	F7W110	F7VUK7	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.943
SMAC_02119	SMAC_06189	F7W110	F7W6A8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.846
SMAC_02119	SMAC_06323	F7W110	F7W6G6	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	WGS project CABT00000000 data, contig 2.34.	0.999