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SMAC_02366 SMAC_02366 SMAC_03990 SMAC_03990 MDE1 MDE1 UTR4 UTR4 SMAC_04834 SMAC_04834 SMAC_07383 SMAC_07383 SMAC_00763 SMAC_00763 SMAC_00870 SMAC_00870 SMAC_08139 SMAC_08139 SMAC_01258 SMAC_01258 SMAC_01760 SMAC_01760 SMAC_01814 SMAC_01814 SMAC_01902 SMAC_01902 MET3 MET3 SMAC_03111 SMAC_03111 SMAC_03391 SMAC_03391 SMAC_03452 SMAC_03452 SMAC_03269 SMAC_03269 SMAC_02849 SMAC_02849 SMAC_02870 SMAC_02870 SMAC_04507 SMAC_04507 SMAC_04156 SMAC_04156 SMAC_03994 SMAC_03994 SMAC_04794 SMAC_04794 SMAC_05116 SMAC_05116 SMAC_02273 SMAC_02273 ADI1 ADI1 SMAC_05583 SMAC_05583 SMAC_05595 SMAC_05595 SMAC_06351 SMAC_06351 SMAC_06935 SMAC_06935 SMAC_07082 SMAC_07082 SMAC_08477 SMAC_08477 SMAC_08891 SMAC_08891 SMAC_09602 SMAC_09602 MRI1 MRI1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene fusions
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SMAC_023663-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1563 aa)
SMAC_03990Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (469 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (273 aa)
UTR4Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (234 aa)
SMAC_04834Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (478 aa)
SMAC_07383Threonine dehydratase. (523 aa)
SMAC_00763Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (316 aa)
SMAC_00870Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (692 aa)
SMAC_08139Tryptophan synthase. (708 aa)
SMAC_01258WGS project CABT00000000 data, contig 2.4; In the N-terminal section; belongs to the acetylglutamate kinase family. (871 aa)
SMAC_017603-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (784 aa)
SMAC_01814Acetolactate synthase. (689 aa)
SMAC_01902Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (445 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
SMAC_03111Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (401 aa)
SMAC_03391Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
SMAC_03452D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (652 aa)
SMAC_03269Phospho-2-dehydro-3-deoxyheptonate aldolase. (379 aa)
SMAC_02849Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (372 aa)
SMAC_02870Histidine biosynthesis trifunctional protein. (870 aa)
SMAC_04507D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (466 aa)
SMAC_04156Chorismate synthase. (432 aa)
SMAC_03994Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa)
SMAC_04794Chorismate mutase. (269 aa)
SMAC_05116Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (733 aa)
SMAC_022731-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (157 aa)
SMAC_05583WGS project CABT00000000 data, contig 2.26. (581 aa)
SMAC_05595Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
SMAC_06351Homoserine dehydrogenase. (348 aa)
SMAC_06935Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (551 aa)
SMAC_070823-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa)
SMAC_08477Phospho-2-dehydro-3-deoxyheptonate aldolase. (373 aa)
SMAC_08891Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (331 aa)
SMAC_09602Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (527 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (388 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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