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SMAC_02366 SMAC_02366 CYN1 CYN1 MDE1 MDE1 SMAC_08712 SMAC_08712 qutE qutE SMAC_04821 SMAC_04821 SMAC_07409 SMAC_07409 SMAC_07383 SMAC_07383 SMAC_01196 SMAC_01196 SMAC_00926 SMAC_00926 SMAC_00940 SMAC_00940 SMAC_01023 SMAC_01023 SMAC_06752 SMAC_06752 acl2 acl2 SMAC_12755 SMAC_12755 SMAC_08139 SMAC_08139 SMAC_01357 SMAC_01357 SMAC_01760 SMAC_01760 SMAC_01940 SMAC_01940 SMAC_05960 SMAC_05960 SMAC_03218 SMAC_03218 SMAC_03179 SMAC_03179 SMAC_03518 SMAC_03518 SMAC_03607 SMAC_03607 SMAC_03609 SMAC_03609 SMAC_03614 SMAC_03614 SMAC_03420 SMAC_03420 SMAC_03451 SMAC_03451 SMAC_03311 SMAC_03311 SMAC_03315 SMAC_03315 PSD1 PSD1 PSD2 PSD2 SMAC_02703 SMAC_02703 SMAC_02914 SMAC_02914 SMAC_04370 SMAC_04370 SMAC_04156 SMAC_04156 SMAC_03801 SMAC_03801 SMAC_03823 SMAC_03823 SMAC_03994 SMAC_03994 SMAC_02060 SMAC_02060 sdh sdh SMAC_02181 SMAC_02181 SMAC_04281 SMAC_04281 SMAC_05116 SMAC_05116 SMAC_05360 SMAC_05360 SMAC_05601 SMAC_05601 NTH1 NTH1 SMAC_07909 SMAC_07909 SMAC_05651 SMAC_05651 SMAC_06596 SMAC_06596 SMAC_06935 SMAC_06935 SMAC_08213 SMAC_08213 SMAC_07347 SMAC_07347 SMAC_09602 SMAC_09602 URA3 URA3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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SMAC_023663-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1563 aa)
CYN1Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (164 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (273 aa)
SMAC_08712Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (237 aa)
qutECatabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (175 aa)
SMAC_04821Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (369 aa)
SMAC_07409WGS project CABT00000000 data, contig 2.1; Belongs to the metallo-dependent hydrolases superfamily. (327 aa)
SMAC_07383Threonine dehydratase. (523 aa)
SMAC_01196WGS project CABT00000000 data, contig 2.2; Belongs to the PAL/histidase family. (635 aa)
SMAC_00926Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (421 aa)
SMAC_00940WGS project CABT00000000 data, contig 2.2. (508 aa)
SMAC_01023WGS project CABT00000000 data, contig 2.2. (766 aa)
SMAC_06752WGS project CABT00000000 data, contig 2.3. (577 aa)
acl2ATP citrate lyase subunit 2. (487 aa)
SMAC_12755Glutamate decarboxylase; Belongs to the group II decarboxylase family. (617 aa)
SMAC_08139Tryptophan synthase. (708 aa)
SMAC_01357Glutamate decarboxylase; Belongs to the group II decarboxylase family. (619 aa)
SMAC_017603-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (784 aa)
SMAC_01940Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (215 aa)
SMAC_05960ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (297 aa)
SMAC_03218WGS project CABT00000000 data, contig 2.7. (560 aa)
SMAC_03179Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (174 aa)
SMAC_03518Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (723 aa)
SMAC_03607Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (394 aa)
SMAC_03609Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (314 aa)
SMAC_03614Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (214 aa)
SMAC_03420Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (234 aa)
SMAC_03451Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (316 aa)
SMAC_03311Rhamnogalacturonate lyase; Belongs to the polysaccharide lyase 4 family. (542 aa)
SMAC_03315Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (347 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (532 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (774 aa)
SMAC_02703Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (406 aa)
SMAC_02914Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (631 aa)
SMAC_04370Isocitrate lyase. (548 aa)
SMAC_04156Chorismate synthase. (432 aa)
SMAC_03801tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (308 aa)
SMAC_03823WGS project CABT00000000 data, contig 2.16; Belongs to the DapA family. (352 aa)
SMAC_03994Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa)
SMAC_02060WGS project CABT00000000 data, contig 2.18; Belongs to the metallo-dependent hydrolases superfamily. (397 aa)
sdhScytalone dehydratase; Belongs to the scytalone dehydratase family. (174 aa)
SMAC_02181WGS project CABT00000000 data, contig 2.18; Belongs to the metallo-dependent hydrolases superfamily. (394 aa)
SMAC_04281Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (233 aa)
SMAC_05116Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (733 aa)
SMAC_05360Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa)
SMAC_05601Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (809 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (805 aa)
SMAC_079093,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (235 aa)
SMAC_05651WGS project CABT00000000 data, contig 2.30; Belongs to the PAL/histidase family. (765 aa)
SMAC_06596WGS project CABT00000000 data, contig 2.37; Belongs to the DapA family. (327 aa)
SMAC_06935Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (551 aa)
SMAC_08213Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (362 aa)
SMAC_07347Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (288 aa)
SMAC_09602Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (527 aa)
URA3Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (396 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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