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UTR4 UTR4 SMAC_09309 SMAC_09309 FEN1 FEN1 SMAC_00014 SMAC_00014 SMAC_00235 SMAC_00235 SMAC_00415 SMAC_00415 SMAC_04828 SMAC_04828 SMAC_04927 SMAC_04927 qaX qaX SMAC_00841 SMAC_00841 SMAC_00999 SMAC_00999 SMAC_01068 SMAC_01068 SMAC_02399 SMAC_02399 SMAC_01314 SMAC_01314 SMAC_01578 SMAC_01578 SMAC_01807 SMAC_01807 SMAC_01814 SMAC_01814 SMAC_12795 SMAC_12795 SMAC_01938 SMAC_01938 SMAC_01952 SMAC_01952 SMAC_05989 SMAC_05989 SMAC_03123 SMAC_03123 SMAC_03111 SMAC_03111 SMAC_05003 SMAC_05003 SMAC_05244 SMAC_05244 SMAC_05212 SMAC_05212 SMAC_05188 SMAC_05188 SMAC_03488 SMAC_03488 SMAC_03492 SMAC_03492 SMAC_03633 SMAC_03633 SMAC_03257 SMAC_03257 SMAC_02663 SMAC_02663 SMAC_06469 SMAC_06469 SMAC_04510 SMAC_04510 SMAC_04505 SMAC_04505 SMAC_04380 SMAC_04380 SMAC_04370 SMAC_04370 SMAC_04018 SMAC_04018 SMAC_04221 SMAC_04221 SMAC_04268 SMAC_04268 SMAC_04284 SMAC_04284 SMAC_04303 SMAC_04303 SMAC_04316 SMAC_04316 SMAC_04763 SMAC_04763 SMAC_05364 SMAC_05364 SMAC_05504 SMAC_05504 SMAC_06516 SMAC_06516 SMAC_07909 SMAC_07909 SMAC_05676 SMAC_05676 SMAC_08988 SMAC_08988 SMAC_06282 SMAC_06282 SMAC_07230 SMAC_07230 SMAC_08401 SMAC_08401 SMAC_09127 SMAC_09127 SMAC_12671 SMAC_12671 ACL1 ACL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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UTR4Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (234 aa)
SMAC_09309Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (430 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (394 aa)
SMAC_00014Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (447 aa)
SMAC_00235Protein phosphatase; Belongs to the PP2C family. (459 aa)
SMAC_00415Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (885 aa)
SMAC_04828Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1222 aa)
SMAC_04927Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
qaXInositol-1-monophosphatase. (239 aa)
SMAC_00841Putative fatty acid synthase alpha subunit reductase; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1822 aa)
SMAC_00999Inositol-1-monophosphatase. (305 aa)
SMAC_01068Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1486 aa)
SMAC_02399Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (901 aa)
SMAC_01314ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (844 aa)
SMAC_01578Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (497 aa)
SMAC_01807Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (335 aa)
SMAC_01814Acetolactate synthase. (689 aa)
SMAC_12795WGS project CABT00000000 data, contig 2.5. (586 aa)
SMAC_01938Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (632 aa)
SMAC_01952Alkaline phosphatase. (596 aa)
SMAC_05989WGS project CABT00000000 data, contig 2.6. (617 aa)
SMAC_03123Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1745 aa)
SMAC_03111Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (401 aa)
SMAC_05003tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (295 aa)
SMAC_05244Magnesium transporter. (548 aa)
SMAC_05212Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1561 aa)
SMAC_05188Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (526 aa)
SMAC_03488WGS project CABT00000000 data, contig 2.9. (576 aa)
SMAC_03492Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (352 aa)
SMAC_03633WGS project CABT00000000 data, contig 2.9. (491 aa)
SMAC_03257Fumarylacetoacetase. (403 aa)
SMAC_02663Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1304 aa)
SMAC_06469Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1293 aa)
SMAC_04510Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
SMAC_04505Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1346 aa)
SMAC_04380Amidophosphoribosyltransferase. (546 aa)
SMAC_04370Isocitrate lyase. (548 aa)
SMAC_04018Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (683 aa)
SMAC_04221WGS project CABT00000000 data, contig 2.19; Belongs to the phosphohexose mutase family. (513 aa)
SMAC_04268Protein phosphatase; Belongs to the PP2C family. (436 aa)
SMAC_04284WGS project CABT00000000 data, contig 2.19. (319 aa)
SMAC_04303Probable acetate kinase. (461 aa)
SMAC_04316S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
SMAC_04763Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (698 aa)
SMAC_05364Glutathione synthetase. (515 aa)
SMAC_05504Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (413 aa)
SMAC_06516WGS project CABT00000000 data, contig 2.28. (449 aa)
SMAC_079093,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (235 aa)
SMAC_05676Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (471 aa)
SMAC_08988Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (326 aa)
SMAC_06282Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (462 aa)
SMAC_07230WGS project CABT00000000 data, contig 2.42. (705 aa)
SMAC_08401Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1317 aa)
SMAC_09127Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (357 aa)
SMAC_12671Uncharacterized protein. (432 aa)
ACL1ATP-citrate synthase subunit 1; Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols; Belongs to the succinate/malate CoA ligase alpha subunit family. (674 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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