STRINGSTRING
SMAC_08690 SMAC_08690 SMAC_06141 SMAC_06141 SMAC_06166 SMAC_06166 SMAC_06167 SMAC_06167 SMAC_06194 SMAC_06194 SMAC_06282 SMAC_06282 SMAC_06283 SMAC_06283 SMAC_06300 SMAC_06300 SMAC_06333 SMAC_06333 SMAC_06582 SMAC_06582 SMAC_06925 SMAC_06925 SMAC_06926 SMAC_06926 SMAC_07153 SMAC_07153 SMAC_08215 SMAC_08215 SMAC_08226 SMAC_08226 SMAC_09143 SMAC_09143 SMAC_07282 SMAC_07282 SMAC_07294 SMAC_07294 SMAC_07857 SMAC_07857 SMAC_08493 SMAC_08493 SMAC_08478 SMAC_08478 SMAC_00145 SMAC_00145 SMAC_00239 SMAC_00239 SMAC_00332 SMAC_00332 SMAC_00395 SMAC_00395 SMAC_00406 SMAC_00406 SMAC_00407 SMAC_00407 SMAC_00527 SMAC_00527 hxB hxB SMAC_04882 SMAC_04882 SMAC_04888 SMAC_04888 SMAC_07437 SMAC_07437 SMAC_01188 SMAC_01188 SMAC_01190 SMAC_01190 COQ5 COQ5 SMAC_00685 SMAC_00685 SMAC_00725 SMAC_00725 SMAC_00862 SMAC_00862 SMAC_00895 SMAC_00895 SMAC_00925 SMAC_00925 SMAC_00947 SMAC_00947 SMAC_00995 SMAC_00995 SMAC_06226 SMAC_06226 SMAC_02313 SMAC_02313 SMAC_06784 SMAC_06784 SMAC_08147 SMAC_08147 SMAC_12623 SMAC_12623 SMAC_01241 SMAC_01241 SMAC_01244 SMAC_01244 SMAC_01282 SMAC_01282 SMAC_01317 SMAC_01317 SMAC_01330 SMAC_01330 SMAC_01344 SMAC_01344 uba4 uba4 SMAC_01578 SMAC_01578 SMAC_01579 SMAC_01579 SMAC_01580 SMAC_01580 SMAC_01929 SMAC_01929 SMAC_06796 SMAC_06796 SMAC_05462 SMAC_05462 COQ6 COQ6 SMAC_05960 SMAC_05960 SMAC_05967 SMAC_05967 SMAC_05978 SMAC_05978 SMAC_06009 SMAC_06009 SMAC_08354 SMAC_08354 SMAC_07518 SMAC_07518 SMAC_03202 SMAC_03202 SMAC_03130 SMAC_03130 SMAC_10080 SMAC_10080 SMAC_09753 SMAC_09753 SMAC_09567 SMAC_09567 SMAC_09446 SMAC_09446 SMAC_09318 SMAC_09318 SMAC_09274 SMAC_09274 SMAC_09261 SMAC_09261 SMAC_09299 SMAC_09299 SMAC_09108 SMAC_09108 SMAC_08723 SMAC_08723 SMAC_03055 SMAC_03055 SMAC_03046 SMAC_03046 SMAC_03045 SMAC_03045 SMAC_03037 SMAC_03037 SMAC_04997 SMAC_04997 SMAC_05026 SMAC_05026 SMAC_05243 SMAC_05243 SMAC_03713 SMAC_03713 SMAC_03437 SMAC_03437 SMAC_03332 SMAC_03332 SMAC_02559 SMAC_02559 SMAC_02592 SMAC_02592 SMAC_02762 SMAC_02762 SMAC_02883 SMAC_02883 cnxH cnxH SMAC_02984 SMAC_02984 SMAC_06704 SMAC_06704 SMAC_06457 SMAC_06457 SMAC_04447 SMAC_04447 SMAC_04445 SMAC_04445 SMAC_04410 SMAC_04410 SMAC_07817 SMAC_07817 SMAC_04097 SMAC_04097 SMAC_03740 SMAC_03740 SMAC_03777 SMAC_03777 SMAC_03778 SMAC_03778 SMAC_03804 SMAC_03804 SMAC_04026 SMAC_04026 SMAC_04035 SMAC_04035 SMAC_02049 SMAC_02049 SMAC_02070 SMAC_02070 SMAC_04522 SMAC_04522 SMAC_04523 SMAC_04523 SMAC_04763 SMAC_04763 cprA cprA SMAC_05065 SMAC_05065 SMAC_05136 SMAC_05136 SMAC_05837 SMAC_05837 SMAC_05863 SMAC_05863 SMAC_05869 SMAC_05869 SMAC_05538 SMAC_05538 SMAC_07582 SMAC_07582 SMAC_07688 SMAC_07688 SMAC_07687 SMAC_07687 SMAC_07685 SMAC_07685 SMAC_07908 SMAC_07908 SMAC_07940 SMAC_07940 SMAC_07941 SMAC_07941 SMAC_05633 SMAC_05633 SMAC_05676 SMAC_05676 SMAC_05695 SMAC_05695 SMAC_05707 SMAC_05707 SMAC_07643 SMAC_07643 SMAC_09000 SMAC_09000 COQ7 COQ7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAC_08690WGS project CABT00000000 data, contig 2.63; Belongs to the cytochrome P450 family. (557 aa)
SMAC_06141WGS project CABT00000000 data, contig 2.33. (240 aa)
SMAC_06166WGS project CABT00000000 data, contig 2.33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (160 aa)
SMAC_06167WGS project CABT00000000 data, contig 2.33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (124 aa)
SMAC_06194Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (317 aa)
SMAC_06282Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (462 aa)
SMAC_06283WGS project CABT00000000 data, contig 2.34. (401 aa)
SMAC_06300WGS project CABT00000000 data, contig 2.34. (1150 aa)
SMAC_06333WGS project CABT00000000 data, contig 2.34; Belongs to the cytochrome b5 family. (139 aa)
SMAC_06582Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (772 aa)
SMAC_06925WGS project CABT00000000 data, contig 2.38; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (452 aa)
SMAC_06926WGS project CABT00000000 data, contig 2.38. (348 aa)
SMAC_07153WGS project CABT00000000 data, contig 2.40. (1110 aa)
SMAC_08215WGS project CABT00000000 data, contig 2.43. (587 aa)
SMAC_08226WGS project CABT00000000 data, contig 2.43. (317 aa)
SMAC_09143WGS project CABT00000000 data, contig 2.43. (319 aa)
SMAC_07282WGS project CABT00000000 data, contig 2.44; Belongs to the 5'-nucleotidase family. (567 aa)
SMAC_07294WGS project CABT00000000 data, contig 2.44; Belongs to the 5'-nucleotidase family. (704 aa)
SMAC_07857WGS project CABT00000000 data, contig 2.49. (451 aa)
SMAC_08493NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (233 aa)
SMAC_08478WGS project CABT00000000 data, contig 2.58. (238 aa)
SMAC_00145WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family. (223 aa)
SMAC_00239WGS project CABT00000000 data, contig 2.1. (386 aa)
SMAC_00332WGS project CABT00000000 data, contig 2.1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (333 aa)
SMAC_00395WGS project CABT00000000 data, contig 2.1. (543 aa)
SMAC_00406WGS project CABT00000000 data, contig 2.1. (803 aa)
SMAC_00407WGS project CABT00000000 data, contig 2.1. (620 aa)
SMAC_00527Putative polyketide synthase protein. (2378 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (801 aa)
SMAC_04882WGS project CABT00000000 data, contig 2.1. (455 aa)
SMAC_04888WGS project CABT00000000 data, contig 2.1. (303 aa)
SMAC_07437WGS project CABT00000000 data, contig 2.1. (537 aa)
SMAC_01188Putative polyketide synthase. (2636 aa)
SMAC_01190WGS project CABT00000000 data, contig 2.2. (350 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (346 aa)
SMAC_00685WGS project CABT00000000 data, contig 2.2. (266 aa)
SMAC_00725WGS project CABT00000000 data, contig 2.2. (798 aa)
SMAC_00862Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (568 aa)
SMAC_00895WGS project CABT00000000 data, contig 2.2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (398 aa)
SMAC_00925WGS project CABT00000000 data, contig 2.2. (615 aa)
SMAC_00947WGS project CABT00000000 data, contig 2.2. (297 aa)
SMAC_00995WGS project CABT00000000 data, contig 2.2. (263 aa)
SMAC_06226WGS project CABT00000000 data, contig 2.3. (334 aa)
SMAC_023134-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (434 aa)
SMAC_06784WGS project CABT00000000 data, contig 2.3. (640 aa)
SMAC_08147WGS project CABT00000000 data, contig 2.3. (161 aa)
SMAC_12623Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (287 aa)
SMAC_01241WGS project CABT00000000 data, contig 2.4; Belongs to the GST superfamily. (342 aa)
SMAC_01244Putative phytoene dehydrogenase AL-1. (597 aa)
SMAC_01282WGS project CABT00000000 data, contig 2.4. (743 aa)
SMAC_01317WGS project CABT00000000 data, contig 2.4. (795 aa)
SMAC_01330WGS project CABT00000000 data, contig 2.4. (475 aa)
SMAC_01344WGS project CABT00000000 data, contig 2.4. (632 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (472 aa)
SMAC_01578Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (497 aa)
SMAC_01579WGS project CABT00000000 data, contig 2.4. (204 aa)
SMAC_01580WGS project CABT00000000 data, contig 2.4. (188 aa)
SMAC_01929WGS project CABT00000000 data, contig 2.5. (771 aa)
SMAC_06796WGS project CABT00000000 data, contig 2.6. (238 aa)
SMAC_05462WGS project CABT00000000 data, contig 2.6. (254 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (490 aa)
SMAC_05960ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (297 aa)
SMAC_05967Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1153 aa)
SMAC_05978WGS project CABT00000000 data, contig 2.6. (267 aa)
SMAC_06009Putative polyketide synthase. (1973 aa)
SMAC_08354Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (725 aa)
SMAC_07518WGS project CABT00000000 data, contig 2.7. (505 aa)
SMAC_03202WGS project CABT00000000 data, contig 2.7; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (595 aa)
SMAC_03130Putative polyketide synthase. (2205 aa)
SMAC_10080WGS project CABT00000000 data, contig 2.323. (301 aa)
SMAC_09753WGS project CABT00000000 data, contig 2.178. (645 aa)
SMAC_09567WGS project CABT00000000 data, contig 2.101. (2252 aa)
SMAC_09446WGS project CABT00000000 data, contig 2.92. (220 aa)
SMAC_09318WGS project CABT00000000 data, contig 2.84. (570 aa)
SMAC_09274WGS project CABT00000000 data, contig 2.81. (353 aa)
SMAC_09261Putative polyketide synthase protein. (2571 aa)
SMAC_09299WGS project CABT00000000 data, contig 2.77. (565 aa)
SMAC_09108WGS project CABT00000000 data, contig 2.72. (297 aa)
SMAC_08723WGS project CABT00000000 data, contig 2.64; Belongs to the FPP/GGPP synthase family. (444 aa)
SMAC_03055WGS project CABT00000000 data, contig 2.7. (293 aa)
SMAC_03046WGS project CABT00000000 data, contig 2.7. (628 aa)
SMAC_03045WGS project CABT00000000 data, contig 2.7. (432 aa)
SMAC_03037WGS project CABT00000000 data, contig 2.7. (261 aa)
SMAC_04997WGS project CABT00000000 data, contig 2.8. (602 aa)
SMAC_05026WGS project CABT00000000 data, contig 2.8. (613 aa)
SMAC_05243WGS project CABT00000000 data, contig 2.8. (426 aa)
SMAC_03713Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (480 aa)
SMAC_03437Putative type III polyketide synthase; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (447 aa)
SMAC_03332WGS project CABT00000000 data, contig 2.10. (170 aa)
SMAC_02559WGS project CABT00000000 data, contig 2.11. (620 aa)
SMAC_02592WGS project CABT00000000 data, contig 2.11. (624 aa)
SMAC_02762WGS project CABT00000000 data, contig 2.11. (657 aa)
SMAC_02883WGS project CABT00000000 data, contig 2.12. (560 aa)
cnxHMolybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (215 aa)
SMAC_02984WGS project CABT00000000 data, contig 2.12. (701 aa)
SMAC_06704WGS project CABT00000000 data, contig 2.13. (449 aa)
SMAC_06457WGS project CABT00000000 data, contig 2.13. (403 aa)
SMAC_04447WGS project CABT00000000 data, contig 2.14. (221 aa)
SMAC_04445WGS project CABT00000000 data, contig 2.14. (699 aa)
SMAC_04410WGS project CABT00000000 data, contig 2.14; Belongs to the mitochondrial carrier (TC 2.A.29) family. (356 aa)
SMAC_07817WGS project CABT00000000 data, contig 2.14. (240 aa)
SMAC_04097WGS project CABT00000000 data, contig 2.15. (1247 aa)
SMAC_03740Putative histidine kinase group protein. (892 aa)
SMAC_03777WGS project CABT00000000 data, contig 2.16. (97 aa)
SMAC_03778WGS project CABT00000000 data, contig 2.16. (212 aa)
SMAC_03804WGS project CABT00000000 data, contig 2.16. (338 aa)
SMAC_04026Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (424 aa)
SMAC_04035WGS project CABT00000000 data, contig 2.17. (364 aa)
SMAC_02049WGS project CABT00000000 data, contig 2.18. (218 aa)
SMAC_02070WGS project CABT00000000 data, contig 2.18. (600 aa)
SMAC_04522WGS project CABT00000000 data, contig 2.20. (435 aa)
SMAC_04523WGS project CABT00000000 data, contig 2.20. (689 aa)
SMAC_04763Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (698 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (692 aa)
SMAC_05065WGS project CABT00000000 data, contig 2.22. (343 aa)
SMAC_05136WGS project CABT00000000 data, contig 2.22. (489 aa)
SMAC_05837WGS project CABT00000000 data, contig 2.24. (267 aa)
SMAC_05863WGS project CABT00000000 data, contig 2.24. (598 aa)
SMAC_05869WGS project CABT00000000 data, contig 2.24. (615 aa)
SMAC_05538WGS project CABT00000000 data, contig 2.26; Belongs to the mitochondrial carrier (TC 2.A.29) family. (467 aa)
SMAC_07582WGS project CABT00000000 data, contig 2.27. (509 aa)
SMAC_07688WGS project CABT00000000 data, contig 2.27. (458 aa)
SMAC_07687WGS project CABT00000000 data, contig 2.27. (364 aa)
SMAC_07685Putative polyketide synthase protein. (2363 aa)
SMAC_07908WGS project CABT00000000 data, contig 2.29. (254 aa)
SMAC_07940WGS project CABT00000000 data, contig 2.29. (254 aa)
SMAC_07941Putative polyketide synthase protein. (2264 aa)
SMAC_05633Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (313 aa)
SMAC_05676Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (471 aa)
SMAC_05695Putative polyketide synthase protein. (2569 aa)
SMAC_05707WGS project CABT00000000 data, contig 2.30; Belongs to the cytochrome P450 family. (554 aa)
SMAC_07643Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (550 aa)
SMAC_09000Putative polyketide synthase protein. (2137 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (256 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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