(38 nodes) HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand network (Sordaria macrospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAC_07005	WGS project CABT00000000 data, contig 2.29. (545 aa)
	SMAC_08900	WGS project CABT00000000 data, contig 2.69; Belongs to the heat shock protein 70 family. (624 aa)
	SMAC_08859	WGS project CABT00000000 data, contig 2.67. (599 aa)
	SMAC_07211	WGS project CABT00000000 data, contig 2.42. (1366 aa)
	SMAC_07800	WGS project CABT00000000 data, contig 2.41. (1068 aa)
	SMAC_07118	WGS project CABT00000000 data, contig 2.39. (218 aa)
	SMAC_06897	Putative dynactin subunit 5 protein. (198 aa)
	SMAC_05549	WGS project CABT00000000 data, contig 2.26. (425 aa)
	SMAC_02067	WGS project CABT00000000 data, contig 2.18. (166 aa)
	SMAC_03981	WGS project CABT00000000 data, contig 2.17. (779 aa)
	SMAC_03979	WGS project CABT00000000 data, contig 2.17. (379 aa)
	SMAC_03913	WGS project CABT00000000 data, contig 2.17. (410 aa)
	SMAC_04445	WGS project CABT00000000 data, contig 2.14. (699 aa)
	SMAC_04447	WGS project CABT00000000 data, contig 2.14. (221 aa)
	SMAC_06671	Putative ropy-2, dynactin arp1 p62 subunit RO-2. (706 aa)
	SMAC_06652	WGS project CABT00000000 data, contig 2.13. (787 aa)
	SMAC_02583	WGS project CABT00000000 data, contig 2.11. (340 aa)
	SMAC_03294	WGS project CABT00000000 data, contig 2.10. (491 aa)
	SMAC_05257	WGS project CABT00000000 data, contig 2.8. (613 aa)
	SMAC_04972	WGS project CABT00000000 data, contig 2.8; Belongs to the heat shock protein 70 family. (632 aa)
	SMAC_03064	WGS project CABT00000000 data, contig 2.7. (450 aa)
	SMAC_08338	WGS project CABT00000000 data, contig 2.7. (721 aa)
	SMAC_06004	WGS project CABT00000000 data, contig 2.6. (550 aa)
	SMAC_06841	WGS project CABT00000000 data, contig 2.6. (237 aa)
	SMAC_01899	WGS project CABT00000000 data, contig 2.5. (427 aa)
	SMAC_01857	WGS project CABT00000000 data, contig 2.5. (234 aa)
	SMAC_01856	WGS project CABT00000000 data, contig 2.5. (483 aa)
	SMAC_01640	WGS project CABT00000000 data, contig 2.4. (431 aa)
	SMAC_01394	WGS project CABT00000000 data, contig 2.4. (576 aa)
	SMAC_01370	WGS project CABT00000000 data, contig 2.4; Belongs to the heat shock protein 70 family. (571 aa)
	SMAC_01341	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (537 aa)
	SMAC_01318	WGS project CABT00000000 data, contig 2.4. (317 aa)
	SMAC_00678	WGS project CABT00000000 data, contig 2.2. (620 aa)
	SMAC_00502	WGS project CABT00000000 data, contig 2.1. (580 aa)
	SMAC_00364	WGS project CABT00000000 data, contig 2.1. (414 aa)
	SMAC_00188	WGS project CABT00000000 data, contig 2.1. (606 aa)
	SMAC_00040	WGS project CABT00000000 data, contig 2.1. (584 aa)
	RTC5	Restriction of telomere capping protein 5; May be involved in a process influencing telomere capping. Belongs to the RTC5 family. (581 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMAC_00040	SMAC_00502	F7VJZ7	F7VLA7	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.1.	0.908
SMAC_00040	SMAC_07005	F7VJZ7	F7W510	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.29.	0.911
SMAC_00364	SMAC_01370	F7VKX0	F7VQM2	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.4; Belongs to the heat shock protein 70 family.	0.881
SMAC_00364	SMAC_01394	F7VKX0	F7VQP6	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.4.	0.868
SMAC_00364	SMAC_01899	F7VKX0	F7VS65	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.5.	0.907
SMAC_00364	SMAC_02067	F7VKX0	F7W0V7	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.18.	0.851
SMAC_00364	SMAC_02583	F7VKX0	F7VWW2	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.11.	0.861
SMAC_00364	SMAC_04445	F7VKX0	F7VYX0	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.14.	0.745
SMAC_00364	SMAC_04447	F7VKX0	F7VYW8	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.14.	0.745
SMAC_00364	SMAC_04972	F7VKX0	F7VUL7	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.8; Belongs to the heat shock protein 70 family.	0.890
SMAC_00364	SMAC_08900	F7VKX0	F7WB19	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.69; Belongs to the heat shock protein 70 family.	0.888
SMAC_00502	SMAC_00040	F7VLA7	F7VJZ7	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.1.	0.908
SMAC_00502	SMAC_07005	F7VLA7	F7W510	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.29.	0.914
SMAC_01318	SMAC_01370	F7VQG9	F7VQM2	WGS project CABT00000000 data, contig 2.4.	WGS project CABT00000000 data, contig 2.4; Belongs to the heat shock protein 70 family.	0.493
SMAC_01318	SMAC_04445	F7VQG9	F7VYX0	WGS project CABT00000000 data, contig 2.4.	WGS project CABT00000000 data, contig 2.14.	0.599
SMAC_01318	SMAC_04447	F7VQG9	F7VYW8	WGS project CABT00000000 data, contig 2.4.	WGS project CABT00000000 data, contig 2.14.	0.599
SMAC_01318	SMAC_04972	F7VQG9	F7VUL7	WGS project CABT00000000 data, contig 2.4.	WGS project CABT00000000 data, contig 2.8; Belongs to the heat shock protein 70 family.	0.493
SMAC_01318	SMAC_08900	F7VQG9	F7WB19	WGS project CABT00000000 data, contig 2.4.	WGS project CABT00000000 data, contig 2.69; Belongs to the heat shock protein 70 family.	0.493
SMAC_01370	SMAC_00364	F7VQM2	F7VKX0	WGS project CABT00000000 data, contig 2.4; Belongs to the heat shock protein 70 family.	WGS project CABT00000000 data, contig 2.1.	0.881
SMAC_01370	SMAC_01318	F7VQM2	F7VQG9	WGS project CABT00000000 data, contig 2.4; Belongs to the heat shock protein 70 family.	WGS project CABT00000000 data, contig 2.4.	0.493