(114 nodes) WD40 repeats network (Sordaria macrospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAC_00085	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (859 aa)
	SMAC_00122	WGS project CABT00000000 data, contig 2.1. (655 aa)
	SMAC_00178	WGS project CABT00000000 data, contig 2.1. (698 aa)
	TRM82	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (577 aa)
	SMAC_00400	WGS project CABT00000000 data, contig 2.1. (595 aa)
	SMAC_00433	WGS project CABT00000000 data, contig 2.1. (988 aa)
	SMAC_00484	WGS project CABT00000000 data, contig 2.1. (507 aa)
	SMAC_04839	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (368 aa)
	SMAC_07427	WGS project CABT00000000 data, contig 2.1. (593 aa)
	SMAC_07399	WGS project CABT00000000 data, contig 2.1. (420 aa)
	SMAC_00646	WGS project CABT00000000 data, contig 2.2; Belongs to the WD repeat SEC13 family. (305 aa)
	SMAC_00888	WGS project CABT00000000 data, contig 2.2. (364 aa)
	SMAC_06224	WGS project CABT00000000 data, contig 2.3. (544 aa)
	SMAC_02324	WGS project CABT00000000 data, contig 2.3. (1028 aa)
	SMAC_02327	Putative AMA1 protein. (807 aa)
	SMAC_02339	WGS project CABT00000000 data, contig 2.3. (445 aa)
	SMAC_02383	WGS project CABT00000000 data, contig 2.3. (1197 aa)
	SMAC_06728	WGS project CABT00000000 data, contig 2.3. (1226 aa)
	SMAC_06749	WGS project CABT00000000 data, contig 2.3. (1190 aa)
	SMAC_01251	WGS project CABT00000000 data, contig 2.4. (412 aa)
	SMAC_01305	WGS project CABT00000000 data, contig 2.4. (1474 aa)
	SMAC_01331	WGS project CABT00000000 data, contig 2.4. (878 aa)
	SMAC_01350	WGS project CABT00000000 data, contig 2.4. (2641 aa)
	SMAC_01475	WGS project CABT00000000 data, contig 2.4. (518 aa)
	SMAC_01566	WGS project CABT00000000 data, contig 2.4. (447 aa)
	SMAC_01567	WGS project CABT00000000 data, contig 2.4. (809 aa)
	SMAC_01629	WGS project CABT00000000 data, contig 2.4. (731 aa)
	SMAC_01690	WGS project CABT00000000 data, contig 2.5. (611 aa)
	SMAC_01770	WGS project CABT00000000 data, contig 2.5; Belongs to the WD repeat SEC13 family. (1039 aa)
	SMAC_01876	WGS project CABT00000000 data, contig 2.5. (358 aa)
	SMAC_01928	WGS project CABT00000000 data, contig 2.5. (519 aa)
	hct1	Putative CDC20/HCT1 protein. (603 aa)
	SMAC_05758	WGS project CABT00000000 data, contig 2.6. (954 aa)
	SMAC_05790	WGS project CABT00000000 data, contig 2.6. (270 aa)
	SMAC_05807	WGS project CABT00000000 data, contig 2.6. (1672 aa)
	SMAC_05993	WGS project CABT00000000 data, contig 2.6. (526 aa)
	SMAC_06001	WGS project CABT00000000 data, contig 2.6. (379 aa)
	SMAC_03096	WGS project CABT00000000 data, contig 2.7. (921 aa)
	SMAC_03013	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (915 aa)
	SMAC_05004	WGS project CABT00000000 data, contig 2.8. (523 aa)
	SMAC_05012	WGS project CABT00000000 data, contig 2.8. (1714 aa)
	SMAC_09060	WGS project CABT00000000 data, contig 2.8. (688 aa)
	SMAC_03496	WGS project CABT00000000 data, contig 2.9. (447 aa)
	SMAC_03535	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1229 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1373 aa)
	SMAC_03339	WGS project CABT00000000 data, contig 2.10. (1091 aa)
	SMAC_02539	WGS project CABT00000000 data, contig 2.11. (787 aa)
	SMAC_02542	WGS project CABT00000000 data, contig 2.11. (1140 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (488 aa)
	SMAC_02638	Putative PI phosphatase group protein. (1215 aa)
	SMAC_02640	WGS project CABT00000000 data, contig 2.11. (897 aa)
	SMAC_02768	WGS project CABT00000000 data, contig 2.12. (795 aa)
	SMAC_02917	WGS project CABT00000000 data, contig 2.12. (526 aa)
	SMAC_02965	WGS project CABT00000000 data, contig 2.12. (567 aa)
	SMAC_04484	WGS project CABT00000000 data, contig 2.14. (795 aa)
	SMAC_04450	WGS project CABT00000000 data, contig 2.14. (800 aa)
	SMAC_04413	WGS project CABT00000000 data, contig 2.14. (909 aa)
	CIA1	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (478 aa)
	SMAC_04201	WGS project CABT00000000 data, contig 2.15. (637 aa)
	SMAC_03744	WGS project CABT00000000 data, contig 2.16. (486 aa)
	SMAC_03965	WGS project CABT00000000 data, contig 2.17. (612 aa)
	SMAC_04054	WGS project CABT00000000 data, contig 2.17. (629 aa)
	SMAC_02058	WGS project CABT00000000 data, contig 2.18. (481 aa)
	SMAC_02139	WGS project CABT00000000 data, contig 2.18. (543 aa)
	SMAC_02159	WGS project CABT00000000 data, contig 2.18. (377 aa)
	SMAC_04241	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa)
	SMAC_04263	WGS project CABT00000000 data, contig 2.19. (1092 aa)
	SMAC_04264	WGS project CABT00000000 data, contig 2.19. (342 aa)
	SMAC_04289	WGS project CABT00000000 data, contig 2.19. (528 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (743 aa)
	SMAC_04637	WGS project CABT00000000 data, contig 2.20. (676 aa)
	SMAC_04689	WGS project CABT00000000 data, contig 2.21. (1249 aa)
	SMAC_04737	WGS project CABT00000000 data, contig 2.21. (484 aa)
	SMAC_04753	WGS project CABT00000000 data, contig 2.21. (1551 aa)
	SMAC_04766	WGS project CABT00000000 data, contig 2.21. (353 aa)
	SMAC_04795	Putative mitochondrial fission protein. (653 aa)
	SMAC_02227	Coronin; Belongs to the WD repeat coronin family. (614 aa)
	SMAC_05867	WGS project CABT00000000 data, contig 2.24. (542 aa)
	SMAC_05282	WGS project CABT00000000 data, contig 2.25. (890 aa)
	SMAC_05318	WGS project CABT00000000 data, contig 2.25. (678 aa)
	SMAC_05324	WGS project CABT00000000 data, contig 2.25. (582 aa)
	SMAC_05505	WGS project CABT00000000 data, contig 2.26. (556 aa)
	SMAC_05598	WGS project CABT00000000 data, contig 2.26. (357 aa)
	PAC1-1	Nuclear distribution protein PAC1-1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (460 aa)
	PAC1-2	Nuclear distribution protein PAC1-2; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (486 aa)
	SMAC_00001	WGS project CABT00000000 data, contig 2.1. (396 aa)
	SMAC_00002	WGS project CABT00000000 data, contig 2.1. (870 aa)
	SMAC_09092	WGS project CABT00000000 data, contig 2.71. (1450 aa)
	SMAC_09217	WGS project CABT00000000 data, contig 2.78. (1392 aa)
	SMAC_09515	WGS project CABT00000000 data, contig 2.96. (758 aa)
	pro11	Striatin Pro11; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity). Required for the formation of mature fruiting bodies during early sexual development. Belongs to the WD repeat striatin family. (845 aa)
	SMAC_05602	WGS project CABT00000000 data, contig 2.26. (318 aa)
	SMAC_06531	WGS project CABT00000000 data, contig 2.28. (564 aa)
	SMAC_08365	WGS project CABT00000000 data, contig 2.28. (316 aa)
	SMAC_06966	WGS project CABT00000000 data, contig 2.29. (564 aa)
	SMAC_07639	WGS project CABT00000000 data, contig 2.31. (316 aa)
	SMAC_07649	WGS project CABT00000000 data, contig 2.31. (355 aa)
	SMAC_06089	WGS project CABT00000000 data, contig 2.32. (976 aa)
	SMAC_06119	WGS project CABT00000000 data, contig 2.33. (615 aa)
	SMAC_06130	WGS project CABT00000000 data, contig 2.33. (643 aa)
	SMAC_06134	WGS project CABT00000000 data, contig 2.33. (618 aa)
	TIF34	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (347 aa)
	SMAC_06367	WGS project CABT00000000 data, contig 2.35. (466 aa)
	SMAC_07111	Putative transcriptional repressor TUP1. (602 aa)
	SMAC_07126	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1005 aa)
	SMAC_07252	Putative SKI8 protein. (357 aa)
	SMAC_07377	WGS project CABT00000000 data, contig 2.45. (1058 aa)
	SMAC_07858	WGS project CABT00000000 data, contig 2.49. (490 aa)
	SMAC_08065	WGS project CABT00000000 data, contig 2.50. (1234 aa)
	SMAC_09496	WGS project CABT00000000 data, contig 2.51. (475 aa)
	SMAC_08479	WGS project CABT00000000 data, contig 2.58. (608 aa)
	SMAC_08603	WGS project CABT00000000 data, contig 2.60. (999 aa)
	SMAC_08631	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (522 aa)
	SMAC_08828	WGS project CABT00000000 data, contig 2.66. (721 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	SMAC_00122	F7W1X7	F7VK80	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.1.	0.527
ERB1	SMAC_00400	F7W1X7	F7VL05	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.1.	0.943
ERB1	SMAC_00433	F7W1X7	F7VL39	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.1.	0.928
ERB1	SMAC_01251	F7W1X7	F7VQA2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.4.	0.976
ERB1	SMAC_01331	F7W1X7	F7VQI2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.4.	0.670
ERB1	SMAC_01475	F7W1X7	F7VQX8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.4.	0.885
ERB1	SMAC_02139	F7W1X7	F7W129	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.18.	0.697
ERB1	SMAC_02327	F7W1X7	F7VP90	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Putative AMA1 protein.	0.527
ERB1	SMAC_02339	F7W1X7	F7VPA4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.3.	0.522
ERB1	SMAC_02640	F7W1X7	F7VX20	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.11.	0.873
ERB1	SMAC_03096	F7W1X7	F7VU87	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.7.	0.909
ERB1	SMAC_03744	F7W1X7	F7VZT9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.16.	0.527
ERB1	SMAC_03965	F7W1X7	F7W0G1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.17.	0.527
ERB1	SMAC_04054	F7W1X7	F7W0Q0	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.17.	0.716
ERB1	SMAC_04201	F7W1X7	F7VZM4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.15.	0.527
ERB1	SMAC_04289	F7W1X7	F7W1E7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.19.	0.832
ERB1	SMAC_04450	F7W1X7	F7VYW5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.14.	0.527
ERB1	SMAC_05505	F7W1X7	F7W3X5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.26.	0.511
ERB1	SMAC_05758	F7W1X7	F7VT58	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.6.	0.814
ERB1	SMAC_05993	F7W1X7	F7VTI4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WGS project CABT00000000 data, contig 2.6.	0.528