STRINGSTRING
SMAC_09309 SMAC_09309 SMAC_00470 SMAC_00470 SMAC_04927 SMAC_04927 SMAC_00772 SMAC_00772 SMAC_00842 SMAC_00842 SMAC_00924 SMAC_00924 SMAC_01039 SMAC_01039 SMAC_01050 SMAC_01050 ADK1 ADK1 SMAC_02469 SMAC_02469 SMAC_02497 SMAC_02497 SMAC_01238 SMAC_01238 SMAC_01239 SMAC_01239 SMAC_01524 SMAC_01524 SMAC_01638 SMAC_01638 SMAC_01739 SMAC_01739 SMAC_01875 SMAC_01875 SMAC_05391 SMAC_05391 MET3 MET3 SMAC_05730 SMAC_05730 SMAC_07514 SMAC_07514 SMAC_04987 SMAC_04987 SMAC_02848 SMAC_02848 SMAC_02858 SMAC_02858 SMAC_02892 SMAC_02892 SMAC_02914 SMAC_02914 ADK2 ADK2 SMAC_08849 SMAC_08849 SMAC_04510 SMAC_04510 SMAC_04509 SMAC_04509 SMAC_04493 SMAC_04493 SMAC_04392 SMAC_04392 SMAC_04380 SMAC_04380 SMAC_04084 SMAC_04084 SMAC_03769 SMAC_03769 SMAC_03806 SMAC_03806 SMAC_03966 SMAC_03966 SMAC_02127 SMAC_02127 SMAC_02161 SMAC_02161 SMAC_04221 SMAC_04221 SMAC_02248 SMAC_02248 SMAC_05360 SMAC_05360 SMAC_06275 SMAC_06275 SMAC_07113 SMAC_07113 SMAC_07771 SMAC_07771 SMAC_08732 SMAC_08732 SMAC_08825 SMAC_08825 SMAC_08917 SMAC_08917 SMAC_09163 SMAC_09163
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAC_09309Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (430 aa)
SMAC_00470WGS project CABT00000000 data, contig 2.1. (1023 aa)
SMAC_04927Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
SMAC_00772WGS project CABT00000000 data, contig 2.2. (323 aa)
SMAC_00842WGS project CABT00000000 data, contig 2.2. (499 aa)
SMAC_00924Bis(5'-adenosyl)-triphosphatase. (299 aa)
SMAC_01039WGS project CABT00000000 data, contig 2.2. (448 aa)
SMAC_01050WGS project CABT00000000 data, contig 2.2. (194 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (278 aa)
SMAC_02469WGS project CABT00000000 data, contig 2.3. (412 aa)
SMAC_02497WGS project CABT00000000 data, contig 2.3. (354 aa)
SMAC_01238WGS project CABT00000000 data, contig 2.4; Belongs to the Nudix hydrolase family. (204 aa)
SMAC_01239WGS project CABT00000000 data, contig 2.4. (332 aa)
SMAC_01524WGS project CABT00000000 data, contig 2.4. (232 aa)
SMAC_01638Putative CR1 protein. (2312 aa)
SMAC_01739WGS project CABT00000000 data, contig 2.5. (483 aa)
SMAC_01875WGS project CABT00000000 data, contig 2.5. (345 aa)
SMAC_05391WGS project CABT00000000 data, contig 2.6. (625 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
SMAC_05730WGS project CABT00000000 data, contig 2.6. (594 aa)
SMAC_07514WGS project CABT00000000 data, contig 2.7. (573 aa)
SMAC_04987WGS project CABT00000000 data, contig 2.8. (226 aa)
SMAC_02848Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (536 aa)
SMAC_02858Urease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (855 aa)
SMAC_02892WGS project CABT00000000 data, contig 2.12. (378 aa)
SMAC_02914Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (631 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (273 aa)
SMAC_08849WGS project CABT00000000 data, contig 2.13. (348 aa)
SMAC_04510Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
SMAC_04509Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (175 aa)
SMAC_044935-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (141 aa)
SMAC_04392Nucleoside diphosphate kinase. (152 aa)
SMAC_04380Amidophosphoribosyltransferase. (546 aa)
SMAC_04084WGS project CABT00000000 data, contig 2.15. (1373 aa)
SMAC_03769WGS project CABT00000000 data, contig 2.16. (1357 aa)
SMAC_03806WGS project CABT00000000 data, contig 2.16; Belongs to the GDA1/CD39 NTPase family. (750 aa)
SMAC_03966WGS project CABT00000000 data, contig 2.17. (501 aa)
SMAC_02127Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (308 aa)
SMAC_02161WGS project CABT00000000 data, contig 2.18. (410 aa)
SMAC_04221WGS project CABT00000000 data, contig 2.19; Belongs to the phosphohexose mutase family. (513 aa)
SMAC_02248WGS project CABT00000000 data, contig 2.23. (762 aa)
SMAC_05360Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa)
SMAC_06275WGS project CABT00000000 data, contig 2.34. (256 aa)
SMAC_07113WGS project CABT00000000 data, contig 2.39. (655 aa)
SMAC_07771Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (937 aa)
SMAC_08732WGS project CABT00000000 data, contig 2.64. (559 aa)
SMAC_08825WGS project CABT00000000 data, contig 2.66; Belongs to the Nudix hydrolase family. (286 aa)
SMAC_08917Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (455 aa)
SMAC_09163WGS project CABT00000000 data, contig 2.74. (520 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
Server load: low (26%) [HD]