22 items (Sordaria macrospora) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	SMAC_00145	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family. (223 aa)
	SMAC_00395	WGS project CABT00000000 data, contig 2.1. (543 aa)
	hxB	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (801 aa)
	SMAC_00953	WGS project CABT00000000 data, contig 2.2. (222 aa)
	SMAC_01578	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (497 aa)
	SMAC_01662	WGS project CABT00000000 data, contig 2.5. (477 aa)
	SMAC_01929	WGS project CABT00000000 data, contig 2.5. (771 aa)
	SMAC_01952	Alkaline phosphatase. (596 aa)
	SMAC_07530	WGS project CABT00000000 data, contig 2.7. (797 aa)
	SMAC_03596	WGS project CABT00000000 data, contig 2.9. (631 aa)
	SMAC_02647	WGS project CABT00000000 data, contig 2.11. (632 aa)
	cnxH	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (215 aa)
	SMAC_07825	WGS project CABT00000000 data, contig 2.14. (269 aa)
	SMAC_04026	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (424 aa)
	SMAC_04763	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (698 aa)
	SMAC_05676	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (471 aa)
	SMAC_06614	WGS project CABT00000000 data, contig 2.37. (235 aa)
	SMAC_06619	WGS project CABT00000000 data, contig 2.37. (972 aa)
	SMAC_06905	WGS project CABT00000000 data, contig 2.38. (378 aa)
	SMAC_09143	WGS project CABT00000000 data, contig 2.43. (319 aa)
	SMAC_08921	WGS project CABT00000000 data, contig 2.69. (635 aa)
	SMAC_09753	WGS project CABT00000000 data, contig 2.178. (645 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMAC_00145	SMAC_01578	F7VKA3	F7VR80	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.977
SMAC_00145	SMAC_01662	F7VKA3	F7VRH7	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family.	WGS project CABT00000000 data, contig 2.5.	0.419
SMAC_00145	SMAC_04026	F7VKA3	F7W0M3	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.977
SMAC_00145	SMAC_09143	F7VKA3	F7W897	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family.	WGS project CABT00000000 data, contig 2.43.	0.446
SMAC_00395	SMAC_04763	F7VL00	F7W2D1	WGS project CABT00000000 data, contig 2.1.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.914
SMAC_00395	SMAC_05676	F7VL00	F7W5C8	WGS project CABT00000000 data, contig 2.1.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.914
SMAC_00395	SMAC_09753	F7VL00	F7WCP5	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.178.	0.900
SMAC_00395	hxB	F7VL00	F7VLQ6	WGS project CABT00000000 data, contig 2.1.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.905
SMAC_00953	SMAC_01929	F7VNK0	F7VS97	WGS project CABT00000000 data, contig 2.2.	WGS project CABT00000000 data, contig 2.5.	0.429
SMAC_00953	SMAC_09143	F7VNK0	F7W897	WGS project CABT00000000 data, contig 2.2.	WGS project CABT00000000 data, contig 2.43.	0.630
SMAC_01578	SMAC_00145	F7VR80	F7VKA3	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family.	0.977
SMAC_01578	SMAC_01662	F7VR80	F7VRH7	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	WGS project CABT00000000 data, contig 2.5.	0.966
SMAC_01578	SMAC_04026	F7VR80	F7W0M3	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.911
SMAC_01578	SMAC_09143	F7VR80	F7W897	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	WGS project CABT00000000 data, contig 2.43.	0.537
SMAC_01662	SMAC_00145	F7VRH7	F7VKA3	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family.	0.419
SMAC_01662	SMAC_01578	F7VRH7	F7VR80	WGS project CABT00000000 data, contig 2.5.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.966
SMAC_01662	SMAC_04026	F7VRH7	F7W0M3	WGS project CABT00000000 data, contig 2.5.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.988
SMAC_01662	SMAC_06614	F7VRH7	F7W735	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.37.	0.900
SMAC_01662	SMAC_06619	F7VRH7	F7W740	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.37.	0.682
SMAC_01662	SMAC_07530	F7VRH7	F7VTQ6	WGS project CABT00000000 data, contig 2.5.	WGS project CABT00000000 data, contig 2.7.	0.682