node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFG34477.1 | AFG34697.1 | Ferpe_0336 | Ferpe_0562 | Dihydropteroate synthase; PFAM: Pterin binding enzyme. | Metal-dependent hydrolase, beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily. | 0.914 |
AFG34477.1 | AFG36074.1 | Ferpe_0336 | Ferpe_2027 | Dihydropteroate synthase; PFAM: Pterin binding enzyme. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | 0.999 |
AFG34697.1 | AFG34477.1 | Ferpe_0562 | Ferpe_0336 | Metal-dependent hydrolase, beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily. | Dihydropteroate synthase; PFAM: Pterin binding enzyme. | 0.914 |
AFG34697.1 | AFG36074.1 | Ferpe_0562 | Ferpe_2027 | Metal-dependent hydrolase, beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | 0.900 |
AFG35568.1 | coaD | Ferpe_1499 | Ferpe_0237 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.930 |
AFG35568.1 | coaE | Ferpe_1499 | Ferpe_1511 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.482 |
AFG35568.1 | coaX | Ferpe_1499 | Ferpe_1464 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.931 |
AFG35568.1 | panB | Ferpe_1499 | Ferpe_1905 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.470 |
AFG35568.1 | panC | Ferpe_1499 | Ferpe_1830 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.876 |
AFG35578.1 | coaE | Ferpe_1510 | Ferpe_1511 | Hypothetical protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.697 |
AFG36074.1 | AFG34477.1 | Ferpe_2027 | Ferpe_0336 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | Dihydropteroate synthase; PFAM: Pterin binding enzyme. | 0.999 |
AFG36074.1 | AFG34697.1 | Ferpe_2027 | Ferpe_0562 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | Metal-dependent hydrolase, beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily. | 0.900 |
AFG36074.1 | coaD | Ferpe_2027 | Ferpe_0237 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.472 |
AFG36074.1 | panB | Ferpe_2027 | Ferpe_1905 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.576 |
AFG36074.1 | panC | Ferpe_2027 | Ferpe_1830 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.556 |
coaD | AFG35568.1 | Ferpe_0237 | Ferpe_1499 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.930 |
coaD | AFG36074.1 | Ferpe_0237 | Ferpe_2027 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. | 0.472 |
coaD | coaE | Ferpe_0237 | Ferpe_1511 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.940 |
coaD | coaX | Ferpe_0237 | Ferpe_1464 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.961 |
coaE | AFG35568.1 | Ferpe_1511 | Ferpe_1499 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.482 |