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| | tdk | PFAM: Thymidine kinase. (200 aa) |
| | AFG35117.1 | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (179 aa) |
| | AFG35130.1 | Transcriptional regulator/sugar kinase; PFAM: ROK family. (295 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa) |
| | AFG35153.1 | Exonuclease, DNA polymerase III, epsilon subunit family; PFAM: Exonuclease. (189 aa) |
| | AFG35185.1 | Fructose-1-phosphate kinase/fructose-6-phosphate kinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (317 aa) |
| | AFG35199.1 | PFAM: Bacterial DNA polymerase III alpha subunit. (840 aa) |
| | AFG35207.1 | Glucose-1-phosphate thymidylyltransferase, short form; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (311 aa) |
| | AFG35236.1 | PFAM: Prokaryotic diacylglycerol kinase. (158 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa) |
| | AFG35252.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GAF domain; GGDEF domain. (773 aa) |
| | AFG35262.1 | PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain. (520 aa) |
| | AFG35346.1 | Putative membrane protein; PFAM: Domain of unknown function (DUF368). (277 aa) |
| | AFG35353.1 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; Belongs to the pyruvate kinase family. (471 aa) |
| | AFG35380.1 | Thiamine diphosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain. (206 aa) |
| | AFG35407.1 | CheY-like receiver domain-containing protein; PFAM: Response regulator receiver domain. (436 aa) |
| | AFG35418.1 | Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (291 aa) |
| | AFG35425.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (278 aa) |
| | AFG35432.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (493 aa) |
| | AFG35438.1 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (743 aa) |
| | AFG35442.1 | Anti-sigma regulatory factor (Ser/Thr protein kinase). (153 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (328 aa) |
| | adk | Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | AFG35502.1 | tRNA nucleotidyltransferase/poly(A) polymerase; PFAM: DHHA1 domain; DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (891 aa) |
| | pfp | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (392 aa) |
| | coaX | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa) |
| | AFG35540.1 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (329 aa) |
| | AFG35556.1 | Putative glycerate kinase; PFAM: MOFRL family. (426 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (179 aa) |
| | AFG35583.1 | PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold. (909 aa) |
| | AFG35630.1 | DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-54, DNA binding domain. (304 aa) |
| | AFG35633.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (508 aa) |
| | AFG35667.1 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa) |
| | AFG35709.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (188 aa) |
| | AFG35717.1 | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; Belongs to the aspartokinase family. (466 aa) |
| | AFG35725.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (355 aa) |
| | AFG35758.1 | PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase. (165 aa) |
| | cobS | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (249 aa) |
| | AFG35818.1 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (333 aa) |
| | AFG35827.1 | 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | AFG35853.1 | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (337 aa) |
| | AFG35914.1 | Nucleoside-diphosphate-sugar pyrophosphorylase family protein; PFAM: Phosphotransferase enzyme family. (498 aa) |
| | AFG35918.1 | Glucose-1-phosphate thymidylylransferase, long form; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats). (359 aa) |
| | AFG35922.1 | Putative regulator of cell autolysis; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (329 aa) |
| | cmk | PFAM: Cytidylate kinase. (226 aa) |
| | polC | DNA polymerase III, alpha chain; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1395 aa) |
| | AFG35977.1 | nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: impB/mucB/samB family. (375 aa) |
| | AFG35981.1 | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (451 aa) |
| | AFG35989.1 | Hypothetical protein; PFAM: PASTA domain. (262 aa) |
| | AFG36006.1 | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (614 aa) |
| | AFG36009.1 | Uncharacterized stress-induced protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732). (291 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (217 aa) |
| | rpoZ | DNA-directed RNA polymerase, subunit K/omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (76 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (269 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | AFG36074.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. (278 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1650 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1182 aa) |
| | AFG36108.1 | PFAM: Amino acid kinase family; Belongs to the carbamate kinase family. (311 aa) |
| | AFG34217.1 | DAK2 domain fusion protein YloV; PFAM: DAK2 domain. (538 aa) |
| | AFG34226.1 | Glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; Protein of unknown function, DUF583; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (371 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (415 aa) |
| | AFG34232.1 | CDP-diglyceride synthetase; PFAM: Cytidylyltransferase family. (287 aa) |
| | AFG34236.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (199 aa) |
| | AFG34243.1 | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (429 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (572 aa) |
| | AFG34263.1 | Uncharacterized protein involved in exopolysaccharide biosynthesis; PFAM: Chain length determinant protein. (673 aa) |
| | AFG34275.1 | Glucose-1-phosphate thymidylyltransferase, short form; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (290 aa) |
| | AFG34289.1 | PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain. (486 aa) |
| | AFG34292.1 | PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain. (516 aa) |
| | AFG34302.1 | Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase. (354 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa) |
| | nadD | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (221 aa) |
| | AFG34333.1 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Belongs to the sigma-70 factor family. (251 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (694 aa) |
| | AFG34348.1 | Riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. (312 aa) |
| | AFG34354.1 | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (470 aa) |
| | AFG34359.1 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (481 aa) |
| | AFG34384.1 | PFAM: DNA polymerase III, delta subunit. (338 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | AFG34395.1 | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4. (316 aa) |
| | AFG34414.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (500 aa) |
| | pgk | PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | AFG34455.1 | PFAM: Amino acid kinase family; manually curated; Belongs to the aspartokinase family. (407 aa) |
| | AFG34466.1 | Putative nucleic-acid-binding protein (contains the HHH domain); PFAM: DisA bacterial checkpoint controller nucleotide-binding; DisA bacterial checkpoint controller linker region; Belongs to the DisA family. (354 aa) |
| | AFG34467.1 | Transcriptional regulator/sugar kinase; PFAM: ROK family. (313 aa) |
| | buk | PFAM: Acetokinase family; Belongs to the acetokinase family. (358 aa) |
| | buk-2 | PFAM: Acetokinase family; Belongs to the acetokinase family. (361 aa) |
| | AFG34513.1 | PFAM: Phosphoribulokinase / Uridine kinase family. (557 aa) |
| | nadK | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa) |
| | AFG34550.1 | Transcriptional regulator/sugar kinase; PFAM: ROK family; IclR helix-turn-helix domain. (380 aa) |
| | AFG34560.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (521 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (897 aa) |
| | AFG34601.1 | PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain. (341 aa) |
| | AFG34611.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (549 aa) |
| | AFG34616.1 | Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (681 aa) |
| | thiI | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (390 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (406 aa) |
| | AFG34638.1 | PFAM: Phosphoribulokinase / Uridine kinase family. (201 aa) |
| | AFG34639.1 | Transcriptional regulator/sugar kinase; PFAM: ROK family. (373 aa) |
| | AFG34645.1 | Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (335 aa) |
| | mraY | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (309 aa) |
| | AFG34650.1 | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4. (309 aa) |
| | AFG34735.1 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (236 aa) |
| | AFG34772.1 | Hypothetical protein; PFAM: Phosphomethylpyrimidine kinase; Archaeal phosphomethylpyrimidine kinase. (409 aa) |
| | AFG34818.1 | Thiamine diphosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain. (206 aa) |
| | AFG34873.1 | GGDEF domain-containing protein; PFAM: GGDEF domain. (143 aa) |
| | dnaX | DNA polymerase III, subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (538 aa) |
| | AFG34902.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: GGDEF domain. (1226 aa) |
| | AFG34960.1 | PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; Belongs to the GHMP kinase family. GalK subfamily. (356 aa) |
| | AFG34961.1 | PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain. (317 aa) |
| | AFG34986.1 | Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: Response regulator receiver domain; GGDEF domain. (471 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (452 aa) |
| | AFG34997.1 | Pyruvate phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Belongs to the PEP-utilizing enzyme family. (881 aa) |
| | AFG35071.1 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (333 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (199 aa) |
| | AFG35097.1 | PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (409 aa) |
