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| | engB | Ribosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (200 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (822 aa) |
| | AFG34359.1 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (481 aa) |
| | AFG34367.1 | ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter. (232 aa) |
| | AFG34378.1 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); Belongs to the ClpA/ClpB family. (739 aa) |
| | era | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (298 aa) |
| | AFG34385.1 | ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter. (238 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | AFG34387.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (448 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (515 aa) |
| | pgk | PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | AFG34423.1 | Iron-only hydrogenase maturation protein HydF; PFAM: GTPase of unknown function. (405 aa) |
| | AFG34425.1 | ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; PFAM: ABC transporter. (248 aa) |
| | AFG34431.1 | Putative iron-only hydrogenase system regulator. (84 aa) |
| | AFG34446.1 | succinyl-CoA synthetase, beta subunit; PFAM: ATP-grasp domain. (355 aa) |
| | AFG34455.1 | PFAM: Amino acid kinase family; manually curated; Belongs to the aspartokinase family. (407 aa) |
| | AFG34466.1 | Putative nucleic-acid-binding protein (contains the HHH domain); PFAM: DisA bacterial checkpoint controller nucleotide-binding; DisA bacterial checkpoint controller linker region; Belongs to the DisA family. (354 aa) |
| | AFG34469.1 | ABC-type (unclassified) transport system, ATPase component; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter. (248 aa) |
| | AFG34479.1 | PFAM: von Willebrand factor type A domain. (348 aa) |
| | buk | PFAM: Acetokinase family; Belongs to the acetokinase family. (358 aa) |
| | buk-2 | PFAM: Acetokinase family; Belongs to the acetokinase family. (361 aa) |
| | AFG34488.1 | Hypothetical protein. (214 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (423 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa) |
| | AFG34509.1 | PFAM: Cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (174 aa) |
| | AFG34513.1 | PFAM: Phosphoribulokinase / Uridine kinase family. (557 aa) |
| | AFG34517.1 | Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain. (562 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (353 aa) |
| | AFG34525.1 | PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus. (418 aa) |
| | AFG34526.1 | Putative phosphatase, C-terminal domain of histone macro H2A1 like protein; PFAM: Macro domain. (192 aa) |
| | AFG34529.1 | ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter. (638 aa) |
| | AFG34530.1 | ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter. (583 aa) |
| | ruvB | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa) |
| | nadK | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (451 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (616 aa) |
| | AFG34545.1 | ATPase component of various ABC-type transport systems with duplicated ATPase domain; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region. (278 aa) |
| | AFG34546.1 | PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; Belongs to the ABC transporter superfamily. (331 aa) |
| | AFG34552.1 | Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; TOBE domain. (369 aa) |
| | AFG34564.1 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. (828 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (467 aa) |
| | AFG34572.1 | Putative flavoprotein; PFAM: Metallo-beta-lactamase superfamily. (259 aa) |
| | mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (811 aa) |
| | AFG34600.1 | ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (268 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (472 aa) |
| | cysS | PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa) |
| | proS | prolyl-tRNA synthetase, family II; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and i [...] (572 aa) |
| | rtcB | PFAM: Uncharacterized protein family UPF0027; Belongs to the RtcB family. (471 aa) |
| | AFG34616.1 | Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (681 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (583 aa) |
| | thiI | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (390 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (406 aa) |
| | AFG34630.1 | Type III secretion system ATPase, FliI/YscN; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain. (447 aa) |
| | AFG34638.1 | PFAM: Phosphoribulokinase / Uridine kinase family. (201 aa) |
| | murE | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (499 aa) |
| | AFG34648.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. (427 aa) |
| | AFG34665.1 | ABC-type transport system involved in Fe-S cluster assembly, ATPase component; PFAM: ABC transporter. (244 aa) |
| | AFG34682.1 | Mismatch repair ATPase (MutS family); PFAM: MutS domain V. (488 aa) |
| | AFG34690.1 | Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1068 aa) |
| | AFG34698.1 | DNA phosphorothioation system restriction enzyme; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. (451 aa) |
| | AFG34700.1 | Hypothetical protein. (663 aa) |
| | AFG34703.1 | PFAM: Type III restriction enzyme, res subunit. (990 aa) |
| | AFG34741.1 | Hypothetical protein. (62 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (525 aa) |
| | AFG34751.1 | NADPH-dependent FMN reductase. (163 aa) |
| | AFG34760.1 | Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; PFAM: ABC transporter. (243 aa) |
| | AFG34761.1 | PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter. (254 aa) |
| | AFG34777.1 | PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain. (95 aa) |
| | atpD | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa) |
| | atpG | ATP synthase, F1 gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (276 aa) |
| | atpA | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (507 aa) |
| | AFG34792.1 | Putative flavoprotein; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin. (397 aa) |
| | AFG34795.1 | Heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase. (786 aa) |
| | AFG34804.1 | ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter. (245 aa) |
| | AFG34810.1 | DNA replication protein; PFAM: IstB-like ATP binding protein. (254 aa) |
| | AFG34812.1 | ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter. (588 aa) |
| | nadE-2 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (575 aa) |
| | AFG34818.1 | Thiamine diphosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain. (206 aa) |
| | AFG34837.1 | Putative integral membrane protein; Manually curated. (163 aa) |
| | guaA-2 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (514 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (422 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa) |
| | AFG34851.1 | DNA replication protein; PFAM: IstB-like ATP binding protein. (254 aa) |
| | AFG34852.1 | Putative ATPase (AAA+ superfamily). (418 aa) |
| | AFG34858.1 | Putative ATPase (AAA+ superfamily); PFAM: Archaeal ATPase. (367 aa) |
| | AFG34862.1 | ATP-grasp enzyme, D-alanine-D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus. (302 aa) |
| | AFG34867.1 | DNA/RNA helicase, superfamily II; PFAM: Type III restriction enzyme, res subunit; manually curated. (836 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (867 aa) |
| | AFG34875.1 | Folylpolyglutamate synthase/dihydrofolate synthase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; Belongs to the folylpolyglutamate synthase family. (436 aa) |
| | rho-2 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (422 aa) |
| | upp-2 | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa) |
| | AFG34890.1 | Pilus retraction protein PilT; PFAM: Type II/IV secretion system protein. (352 aa) |
| | dnaX | DNA polymerase III, subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (538 aa) |
| | miaA | tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa) |
| | AFG34896.1 | Putative S-layer protein; PFAM: S-layer homology domain. (425 aa) |
| | AFG34907.1 | PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain. (445 aa) |
| | AFG34909.1 | Ferrous iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (633 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (393 aa) |
| | AFG34917.1 | ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter. (250 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (691 aa) |
| | AFG34951.1 | ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter. (274 aa) |
| | AFG34960.1 | PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; Belongs to the GHMP kinase family. GalK subfamily. (356 aa) |
| | AFG34966.1 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (844 aa) |
| | AFG34975.1 | NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain. (634 aa) |
| | AFG34979.1 | Mg chelatase-related protein; PFAM: Magnesium chelatase, subunit ChlI. (507 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | AFG34997.1 | Pyruvate phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Belongs to the PEP-utilizing enzyme family. (881 aa) |
| | AFG35019.1 | Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC; PFAM: FMN-binding domain. (202 aa) |
| | AFG35023.1 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (548 aa) |
| | ffh | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (434 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (643 aa) |
| | AFG35060.1 | DNA/RNA helicase, superfamily I; PFAM: UvrD/REP helicase. (648 aa) |
| | AFG35066.1 | Putative S-layer protein; PFAM: S-layer homology domain. (970 aa) |
| | AFG35068.1 | ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter. (293 aa) |
| | AFG35071.1 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (333 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (199 aa) |
| | AFG35089.1 | Putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain. (375 aa) |
| | gltX-2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (456 aa) |
| | AFG35095.1 | Putative GTPase. (447 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (827 aa) |
| | metG | Protein containing C-terminal region/beta chain of methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (653 aa) |
| | tdk | PFAM: Thymidine kinase. (200 aa) |
| | ruvA | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (187 aa) |
| | AFG35131.1 | Transcriptional regulator; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. (278 aa) |
| | AFG35132.1 | Putative phosphosugar isomerase; PFAM: SIS domain. (311 aa) |
| | AFG35135.1 | PFAM: ATPase family associated with various cellular activities (AAA). (312 aa) |
| | AFG35148.1 | Putative GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (270 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa) |
| | AFG35150.1 | Hypothetical protein. (819 aa) |
| | AFG35152.1 | PFAM: PhoH-like protein. (412 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (603 aa) |
| | clpX | Endopeptidase Clp ATP-binding regulatory subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (410 aa) |
| | AFG35176.1 | DNA replication protein; PFAM: IstB-like ATP binding protein. (254 aa) |
| | AFG35178.1 | ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter. (573 aa) |
| | AFG35179.1 | ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter. (564 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (641 aa) |
| | AFG35186.1 | ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component. (242 aa) |
| | AFG35201.1 | Phosphate starvation-inducible protein PhoH, predicted ATPase; PFAM: PhoH-like protein. (321 aa) |
| | AFG35215.1 | Glycine betaine/L-proline transport ATP binding subunit; PFAM: ABC transporter; CBS domain. (374 aa) |
| | AFG35217.1 | NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain. (537 aa) |
| | AFG35219.1 | NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain. (609 aa) |
| | AFG35229.1 | ATPase involved in DNA repair; May be involved in recombinational repair of damaged DNA. (510 aa) |
| | AFG35234.1 | Putative S-layer protein; PFAM: S-layer homology domain. (469 aa) |
| | AFG35236.1 | PFAM: Prokaryotic diacylglycerol kinase. (158 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa) |
| | AFG35253.1 | ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter. (596 aa) |
| | AFG35282.1 | ATPase component of Mn/Zn ABC-type transporter; PFAM: ABC transporter. (253 aa) |
| | AFG35294.1 | Amino acid ABC transporter ATP-binding protein, PAAT family; PFAM: ABC transporter. (260 aa) |
| | glyS | PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain. (670 aa) |
| | glyQ | PFAM: Glycyl-tRNA synthetase alpha subunit. (284 aa) |
| | AFG35343.1 | Putative GTPase, probable translation factor; PFAM: Protein of unknown function (DUF933). (354 aa) |
| | pheS | phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (333 aa) |
| | AFG35353.1 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; Belongs to the pyruvate kinase family. (471 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (778 aa) |
| | AFG35361.1 | MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain. (261 aa) |
| | nnrE | yjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...] (508 aa) |
| | AFG35380.1 | Thiamine diphosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain. (206 aa) |
| | AFG35384.1 | ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter. (579 aa) |
| | pheT | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (780 aa) |
| | AFG35400.1 | Cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein. (336 aa) |
| | AFG35418.1 | Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (291 aa) |
| | AFG35433.1 | ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region. (600 aa) |
| | fhs | Formyltetrahydrofolate synthetase; PFAM: Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (555 aa) |
| | AFG35445.1 | ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component; PFAM: ABC transporter. (261 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (400 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; PFAM: SAICAR synthetase. (235 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (82 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (219 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (599 aa) |
| | AFG35453.1 | Hypothetical protein. (358 aa) |
| | adk | Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | tuf | Translation elongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa) |
| | fusA | Translation elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] (692 aa) |
| | AFG35507.1 | Putative metal-sulfur cluster biosynthetic enzyme; PFAM: Domain of unknown function DUF59. (102 aa) |
| | pfp | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (392 aa) |
| | AFG35527.1 | PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; Belongs to the ABC transporter superfamily. (331 aa) |
| | AFG35528.1 | PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; Belongs to the ABC transporter superfamily. (333 aa) |
| | coaX | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa) |
| | AFG35539.1 | Putative P-loop-containing kinase; Displays ATPase and GTPase activities. (282 aa) |
| | nrdR | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (156 aa) |
| | lysS | lysyl-tRNA synthetase (class II); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (829 aa) |
| | AFG35562.1 | Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; PFAM: ABC transporter. (236 aa) |
| | AFG35563.1 | Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter. (293 aa) |
| | AFG35568.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (389 aa) |
| | AFG35572.1 | Putative transcriptional regulator containing the HTH domain; PFAM: Putative transcriptional regulators (Ypuh-like). (243 aa) |
| | AFG35573.1 | ATPase family protein associated with various cellular activities (AAA); PFAM: AAA domain (dynein-related subfamily). (350 aa) |
| | pgi | PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (453 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (179 aa) |
| | nadE-3 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (288 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (604 aa) |
| | AFG35591.1 | PFAM: tRNA synthetases class I (W and Y); Belongs to the class-I aminoacyl-tRNA synthetase family. (327 aa) |
| | AFG35593.1 | Putative ATPase (AAA+ superfamily). (460 aa) |
| | rgy | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1146 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (342 aa) |
| | AFG35604.1 | CRISPR-associated protein, Cmr2 family; PFAM: CRISPR-associated protein. (830 aa) |
| | AFG35621.1 | CRISPR-associated protein, Csm1 family; PFAM: HD domain. (826 aa) |
| | AFG35624.1 | Hypothetical protein. (498 aa) |
| | dnaK | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (597 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (690 aa) |
| | asnS | PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain. (433 aa) |
| | AFG35663.1 | Ribosome biogenesis GTPase YqeH; PFAM: GTPase of unknown function. (370 aa) |
| | AFG35669.1 | ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter. (285 aa) |
| | AFG35673.1 | LAO/AO transport system ATPase; PFAM: ArgK protein. (322 aa) |
| | AFG35683.1 | acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Biotin-requiring enzyme. (143 aa) |
| | secA | Preprotein translocase subunit SecA (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (869 aa) |
| | recA | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (356 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (405 aa) |
| | AFG35717.1 | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; Belongs to the aspartokinase family. (466 aa) |
| | AFG35727.1 | ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter. (227 aa) |
| | AFG35741.1 | FeS assembly ATPase SufC; PFAM: ABC transporter. (253 aa) |
| | AFG35744.1 | ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter. (290 aa) |
| | AFG35745.1 | ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter. (265 aa) |
| | AFG35749.1 | Monosaccharide ABC transporter ATP-binding protein, CUT2 family; PFAM: ABC transporter. (534 aa) |
| | AFG35758.1 | PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase. (165 aa) |
| | AFG35764.1 | PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (178 aa) |
| | AFG35779.1 | PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase. (533 aa) |
| | AFG35786.1 | ATP-dependent exonuclase V beta subunit, helicase and exonuclease domain-containing; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1222 aa) |
| | AFG35787.1 | PFAM: UvrD/REP helicase. (1127 aa) |
| | AFG35792.1 | PP-loop superfamily ATP-utilizing enzyme; PFAM: ATP-binding region. (216 aa) |
| | AFG35818.1 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (333 aa) |
| | AFG35824.1 | PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase. (727 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (912 aa) |
| | AFG35845.1 | Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (119 aa) |
| | pstB | Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (252 aa) |
| | infB-2 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (684 aa) |
| | AFG35857.1 | PFAM: Phosphoenolpyruvate carboxykinase. (543 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa) |
| | priA | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (779 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (280 aa) |
| | AFG35886.1 | PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; Belongs to the ABC transporter superfamily. (333 aa) |
| | AFG35887.1 | PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; Belongs to the ABC transporter superfamily. (332 aa) |
| | AFG35913.1 | Putative sugar phosphate isomerase involved in capsule formation; PFAM: SIS domain. (196 aa) |
| | hisS | PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T). (421 aa) |
| | AFG35919.1 | PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain. (456 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (379 aa) |
| | der | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (467 aa) |
| | cmk | PFAM: Cytidylate kinase. (226 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (573 aa) |
| | AFG35939.1 | Conserved protein of DIM6/NTAB family; PFAM: Flavin reductase like domain. (193 aa) |
| | gatA | glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (464 aa) |
| | gatB | glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (479 aa) |
| | AFG35946.1 | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (447 aa) |
| | smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1164 aa) |
| | AFG35948.1 | PAS domain S-box; PFAM: PAS fold. (408 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (616 aa) |
| | AFG35965.1 | Hypothetical protein. (302 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (404 aa) |
| | AFG35972.1 | Putative S-layer protein; PFAM: S-layer homology domain. (429 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (420 aa) |
| | AFG35979.1 | Putative integral membrane protein; PFAM: VanZ like family. (184 aa) |
| | AFG35989.1 | Hypothetical protein; PFAM: PASTA domain. (262 aa) |
| | rsgA | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (295 aa) |
| | AFG36004.1 | Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (210 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (217 aa) |
| | AFG36016.1 | Phosphoribosylamine-glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain. (413 aa) |
| | AFG36017.1 | Phosphoribosylaminoimidazole (AIR) synthetase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain. (330 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (269 aa) |
| | AFG36022.1 | Putative ATP-dependent protease; PFAM: Lon protease (S16) C-terminal proteolytic domain. (793 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | AFG36074.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 4'-phosphopantetheinyl transferase superfamily; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); Belongs to the P-Pant transferase superfamily. (278 aa) |
| | tmcAL | Putative nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (423 aa) |
| | mfd | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (929 aa) |
| | AFG36083.1 | Septum site-determining protein MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (270 aa) |
| | ftsY | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (306 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (362 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1182 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (449 aa) |
| | AFG34168.1 | ATPase component of uncharacterized ABC-type transporter; PFAM: ABC transporter. (529 aa) |
| | AFG34181.1 | PAS domain S-box; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold. (567 aa) |
| | groS | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (89 aa) |
| | groL | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (538 aa) |
| | AFG34191.1 | PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV. (685 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (937 aa) |
| | leuS | PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Belongs to the class-I aminoacyl-tRNA synthetase family. (818 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | gatC | glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (94 aa) |
| | AFG34226.1 | Glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; Protein of unknown function, DUF583; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (371 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (415 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (867 aa) |
| | AFG34234.1 | Cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein. (337 aa) |
| | AFG34263.1 | Uncharacterized protein involved in exopolysaccharide biosynthesis; PFAM: Chain length determinant protein. (673 aa) |
| | AFG34283.1 | Putative ATPase (AAA+ superfamily); PFAM: Archaeal ATPase. (372 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa) |
| | AFG34309.1 | Monosaccharide ABC transporter ATP-binding protein, CUT2 family; PFAM: ABC transporter. (492 aa) |
| | obg | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (438 aa) |
| | nadD | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (221 aa) |
| | potA | Spermidine/putrescine ABC transporter ATP-binding subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (371 aa) |
| | mnmE | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (508 aa) |
| | AFG34327.1 | Flagellar biosynthetic protein FlhF; PFAM: SRP54-type protein, GTPase domain. (372 aa) |
| | AFG34328.1 | ATPase involved in chromosome partitioning; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (278 aa) |
| | AFG34330.1 | Putative glycosyltransferase; PFAM: PilZ domain. (222 aa) |
| | rnfG | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (233 aa) |
| | hslU | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (466 aa) |
| | AFG34348.1 | Riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. (312 aa) |
| | argS | arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R). (542 aa) |
