(6 nodes) Mixed, incl. Septin cytoskeleton, and Pinocytosis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100177240	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family. (190 aa)
	erk3/4	Protein kinase domain-containing protein. (906 aa)
	mapkk3/6	Protein kinase domain-containing protein. (348 aa)
	F6WQ08_CIOIN	Protein kinase domain-containing protein. (473 aa)
	LOC100178703	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
	Erk5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (820 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Erk5	F6WQ08_CIOIN	ENSCINP00000019973	ENSCINP00000011785	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.715
Erk5	LOC100177240	ENSCINP00000019973	ENSCINP00000001149	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	0.433
Erk5	LOC100178703	ENSCINP00000019973	ENSCINP00000016755	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.894
Erk5	mapkk3/6	ENSCINP00000019973	ENSCINP00000005492	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.888
F6WQ08_CIOIN	Erk5	ENSCINP00000011785	ENSCINP00000019973	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.715
F6WQ08_CIOIN	LOC100177240	ENSCINP00000011785	ENSCINP00000001149	Protein kinase domain-containing protein.	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	0.855
F6WQ08_CIOIN	erk3/4	ENSCINP00000011785	ENSCINP00000002522	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.893
F6WQ08_CIOIN	mapkk3/6	ENSCINP00000011785	ENSCINP00000005492	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.521
LOC100177240	Erk5	ENSCINP00000001149	ENSCINP00000019973	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.433
LOC100177240	F6WQ08_CIOIN	ENSCINP00000001149	ENSCINP00000011785	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	Protein kinase domain-containing protein.	0.855
LOC100177240	LOC100178703	ENSCINP00000001149	ENSCINP00000016755	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.893
LOC100177240	erk3/4	ENSCINP00000001149	ENSCINP00000002522	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	Protein kinase domain-containing protein.	0.503
LOC100178703	Erk5	ENSCINP00000016755	ENSCINP00000019973	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.894
LOC100178703	LOC100177240	ENSCINP00000016755	ENSCINP00000001149	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	0.893
LOC100178703	erk3/4	ENSCINP00000016755	ENSCINP00000002522	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.685
LOC100178703	mapkk3/6	ENSCINP00000016755	ENSCINP00000005492	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.692
erk3/4	F6WQ08_CIOIN	ENSCINP00000002522	ENSCINP00000011785	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.893
erk3/4	LOC100177240	ENSCINP00000002522	ENSCINP00000001149	Protein kinase domain-containing protein.	Alpha-crystallin A chain-like; Belongs to the small heat shock protein (HSP20) family.	0.503
erk3/4	LOC100178703	ENSCINP00000002522	ENSCINP00000016755	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.685
erk3/4	mapkk3/6	ENSCINP00000002522	ENSCINP00000005492	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.725