(70 nodes) Mixed, incl. Axonemal microtubule, and Tubulin/FtsZ family, GTPase domain network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ic5	DC2-related axonemal dynein intermediate chain 5. (548 aa)
	LOC100185176	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	F6YUP1_CIOIN	Uncharacterized protein. (166 aa)
	F6WWC7_CIOIN	Uncharacterized protein; Belongs to the tubulin family. (464 aa)
	F6S888_CIOIN	Uncharacterized protein. (192 aa)
	F7AA31_CIOIN	G_PROTEIN_RECEP_F3_4 domain-containing protein. (906 aa)
	pf-rib	Protofilament ribbon protein. (379 aa)
	LOC100182328	Chitinase domain-containing protein 1; Belongs to the glycosyl hydrolase 18 family. (395 aa)
	LOC100186452	Tektin-1-like. (402 aa)
	F7ABK2_CIOIN	Uncharacterized protein. (585 aa)
	LOC100185418	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (189 aa)
	LOC100176448	Protein C9orf135-like. (224 aa)
	F7AB73_CIOIN	Uncharacterized protein. (1887 aa)
	ci-cmub116	Radial spoke protein CMUB116. (765 aa)
	LOC100180876	Uncharacterized protein C1orf158 homolog. (227 aa)
	F6Y3N8_CIOIN	EF-hand domain-containing protein. (283 aa)
	LOC100177721	WD_REPEATS_REGION domain-containing protein. (620 aa)
	tektinA1	Uncharacterized protein. (447 aa)
	LOC100176736	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
	efhc2	EFHC2 protein. (741 aa)
	F6PR08_CIOIN	Uncharacterized protein. (310 aa)
	ciic3	Thioredoxin domain-containing protein 3 homolog; May be required during the final stages of sperm tail maturation. May act by reducing disulfide bonds within the sperm components (By similarity). (653 aa)
	F6TDK2_CIOIN	Uncharacterized protein. (567 aa)
	F7A7P7_CIOIN	Enkurin domain-containing protein. (258 aa)
	F6XBA5_CIOIN	Uncharacterized protein. (497 aa)
	F6YAM0_CIOIN	Uncharacterized protein. (861 aa)
	LOC100184511	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	LOC100183624	Uncharacterized protein. (1303 aa)
	LOC100180562	UPF0686 protein C11orf1 homolog. (156 aa)
	LOC101242512	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	F6ZJZ6_CIOIN	Uncharacterized protein. (1885 aa)
	LOC100182743	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	F7A2F3_CIOIN	Uncharacterized protein. (157 aa)
	LOC100181688	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	calx	Calaxin. (203 aa)
	LOC100177416	Sperm-associated antigen 8-like. (201 aa)
	LOC100181820	Fumarylacetoacetate hydrolase domain-containing protein 2. (315 aa)
	LOC100179722	Uncharacterized protein. (526 aa)
	LOC100181072	Microtubule-associated protein RP/EB family member 1 isoform X4. (309 aa)
	F6SZQ0_CIOIN	Uncharacterized protein; Belongs to the actin family. (375 aa)
	F6SZN1_CIOIN	Calponin-homology (CH) domain-containing protein. (183 aa)
	F6QB29_CIOIN	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	LOC100178709	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	LOC100185443	Protein Flattop-like. (217 aa)
	LOC100181281	Uncharacterized protein. (520 aa)
	LOC100175467	Cilia- and flagella-associated protein 20 isoform X2. (192 aa)
	F6SXQ6_CIOIN	Uncharacterized protein. (1041 aa)
	F6PLJ3_CIOIN	Uncharacterized protein. (112 aa)
	LOC100182355	Protein FAM166B-like. (287 aa)
	LOC100186959	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	F6RLP1_CIOIN	Uncharacterized protein. (546 aa)
	Ic4	Uncharacterized protein. (550 aa)
	F6TT48_CIOIN	Uncharacterized protein. (194 aa)
	LOC100185469	Uncharacterized protein. (139 aa)
	F6UC91_CIOIN	Uncharacterized protein; Belongs to the actin family. (326 aa)
	F7AR88_CIOIN	Uncharacterized protein. (229 aa)
	F6UZ38_CIOIN	Uncharacterized protein. (203 aa)
	F6SY22_CIOIN	Uncharacterized protein. (307 aa)
	F6SIS7_CIOIN	Uncharacterized protein. (282 aa)
	F6S502_CIOIN	Uncharacterized protein. (85 aa)
	LOC104265377	14-3-3-like protein 2; Belongs to the 14-3-3 family. (253 aa)
	LOC100187227	Uncharacterized protein C5orf49. (147 aa)
	H2XMC6_CIOIN	Uncharacterized protein. (496 aa)
	H2XN32_CIOIN	Uncharacterized protein. (302 aa)
	H2XNK3_CIOIN	Uncharacterized protein. (1478 aa)
	H2XT39_CIOIN	Uncharacterized protein. (494 aa)
	LOC100182799	Uncharacterized protein. (144 aa)
	LOC100177695	Uncharacterized protein. (236 aa)
	LOC100176209	Uncharacterized protein. (311 aa)
	H2XZ21_CIOIN	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (220 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PLJ3_CIOIN	F6UC91_CIOIN	ENSCINP00000020203	ENSCINP00000024954	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.537
F6PLJ3_CIOIN	F6UZ38_CIOIN	ENSCINP00000020203	ENSCINP00000026277	Uncharacterized protein.	Uncharacterized protein.	0.465
F6PLJ3_CIOIN	H2XZ21_CIOIN	ENSCINP00000020203	ENSCINP00000034905	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.724
F6PLJ3_CIOIN	LOC100184511	ENSCINP00000020203	ENSCINP00000014333	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.629
F6PLJ3_CIOIN	LOC100185418	ENSCINP00000020203	ENSCINP00000007984	Uncharacterized protein.	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family.	0.432
F6PLJ3_CIOIN	LOC100186959	ENSCINP00000020203	ENSCINP00000023216	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.424
F6PLJ3_CIOIN	LOC101242512	ENSCINP00000020203	ENSCINP00000015540	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.629
F6PLJ3_CIOIN	LOC104265377	ENSCINP00000020203	ENSCINP00000028764	Uncharacterized protein.	14-3-3-like protein 2; Belongs to the 14-3-3 family.	0.444
F6PR08_CIOIN	F6SXQ6_CIOIN	ENSCINP00000013095	ENSCINP00000019488	Uncharacterized protein.	Uncharacterized protein.	0.415
F6PR08_CIOIN	F6YAM0_CIOIN	ENSCINP00000013095	ENSCINP00000014178	Uncharacterized protein.	Uncharacterized protein.	0.647
F6PR08_CIOIN	LOC100182799	ENSCINP00000013095	ENSCINP00000033672	Uncharacterized protein.	Uncharacterized protein.	0.641
F6PR08_CIOIN	LOC100187227	ENSCINP00000013095	ENSCINP00000029836	Uncharacterized protein.	Uncharacterized protein C5orf49.	0.556
F6PR08_CIOIN	calx	ENSCINP00000013095	ENSCINP00000015983	Uncharacterized protein.	Calaxin.	0.635
F6PR08_CIOIN	ci-cmub116	ENSCINP00000013095	ENSCINP00000010559	Uncharacterized protein.	Radial spoke protein CMUB116.	0.612
F6QB29_CIOIN	F6RLP1_CIOIN	ENSCINP00000018124	ENSCINP00000023931	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.405
F6QB29_CIOIN	F6S888_CIOIN	ENSCINP00000018124	ENSCINP00000002991	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.669
F6QB29_CIOIN	F6WWC7_CIOIN	ENSCINP00000018124	ENSCINP00000002530	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein; Belongs to the tubulin family.	0.675
F6QB29_CIOIN	F6Y3N8_CIOIN	ENSCINP00000018124	ENSCINP00000011460	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	EF-hand domain-containing protein.	0.420
F6QB29_CIOIN	F6ZJZ6_CIOIN	ENSCINP00000018124	ENSCINP00000015580	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.550
F6QB29_CIOIN	F7A7P7_CIOIN	ENSCINP00000018124	ENSCINP00000013781	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Enkurin domain-containing protein.	0.431