(49 nodes) Early endosome, and Mon1-Ccz1 complex network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100185122	Uncharacterized protein. (863 aa)
	LOC101243181	Uncharacterized protein. (214 aa)
	F6ZS04_CIOIN	Uncharacterized protein. (423 aa)
	F6Q8V1_CIOIN	FYVE-type domain-containing protein. (243 aa)
	LOC100177212	Uncharacterized protein. (227 aa)
	LOC100182193	Ras-related protein Rab-5B. (217 aa)
	F6WUM1_CIOIN	Uncharacterized protein. (774 aa)
	Ci-ZF(FYVE)-5	Zinc finger protein. (607 aa)
	Zf(fyve)-5	ANK_REP_REGION domain-containing protein. (226 aa)
	F6Z9J5_CIOIN	WD_REPEATS_REGION domain-containing protein. (732 aa)
	F6YQ60_CIOIN	SAC domain-containing protein. (706 aa)
	F7BBV8_CIOIN	CNH domain-containing protein. (856 aa)
	F6ZHS2_CIOIN	Uncharacterized protein. (484 aa)
	LOC100178332	Ras-related protein Rab-9B-like. (206 aa)
	F6PRZ9_CIOIN	Vps8 domain-containing protein. (1238 aa)
	F6Q2U2_CIOIN	CNH domain-containing protein. (871 aa)
	F6SZ37_CIOIN	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (844 aa)
	LOC100180059	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (626 aa)
	F6T7Y2_CIOIN	Uncharacterized protein. (126 aa)
	F6SXW5_CIOIN	Uncharacterized protein. (1463 aa)
	F6XJU3_CIOIN	Uncharacterized protein. (1922 aa)
	F6ZFS1_CIOIN	Uncharacterized protein. (327 aa)
	F7BKM3_CIOIN	Uncharacterized protein. (506 aa)
	Zf(fyve)-6	Uncharacterized protein. (1125 aa)
	F6YU56_CIOIN	Uncharacterized protein. (351 aa)
	zf(ring)-20	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (841 aa)
	LOC100181521	Pleckstrin homology domain-containing family M member 1-like isoform X1. (814 aa)
	F7AK80_CIOIN	Uncharacterized protein. (382 aa)
	LOC100176004	PH domain-containing protein. (214 aa)
	F7A1B7_CIOIN	Uncharacterized protein. (185 aa)
	H2XJG0_CIOIN	Rabaptin domain-containing protein. (368 aa)
	LOC100186755	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (598 aa)
	H2XPJ6_CIOIN	Uncharacterized protein. (446 aa)
	H2XPL4_CIOIN	Uncharacterized protein. (168 aa)
	H2XPZ4_CIOIN	BEACH domain-containing protein. (200 aa)
	H2XQC5_CIOIN	Uncharacterized protein. (227 aa)
	H2XRF4_CIOIN	Uncharacterized protein. (451 aa)
	H2XUT4_CIOIN	Rab5-bind domain-containing protein. (264 aa)
	LOC100180756	Ras-related protein RABF2b-like. (215 aa)
	LOC100176528	ADP-ribosylation factor-like protein 8B-A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	LOC100185024	Spermatogenesis-defective protein 39 homolog. (499 aa)
	H2XWW7_CIOIN	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (546 aa)
	H2XX14_CIOIN	Uncharacterized protein. (116 aa)
	H2XXR8_CIOIN	Uncharacterized protein. (379 aa)
	H2XZ06_CIOIN	Uncharacterized protein. (231 aa)
	H2Y130_CIOIN	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (563 aa)
	H2Y2U9_CIOIN	Uncharacterized protein. (884 aa)
	H2Y371_CIOIN	FYVE-type domain-containing protein. (419 aa)
	H2Y397_CIOIN	Uncharacterized protein. (618 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ci-ZF(FYVE)-5	F6Q8V1_CIOIN	ENSCINP00000008513	ENSCINP00000004983	Zinc finger protein.	FYVE-type domain-containing protein.	0.525
Ci-ZF(FYVE)-5	F6SXW5_CIOIN	ENSCINP00000008513	ENSCINP00000019481	Zinc finger protein.	Uncharacterized protein.	0.528
Ci-ZF(FYVE)-5	F7A1B7_CIOIN	ENSCINP00000008513	ENSCINP00000029064	Zinc finger protein.	Uncharacterized protein.	0.660
Ci-ZF(FYVE)-5	F7BKM3_CIOIN	ENSCINP00000008513	ENSCINP00000024722	Zinc finger protein.	Uncharacterized protein.	0.564
Ci-ZF(FYVE)-5	H2XJG0_CIOIN	ENSCINP00000008513	ENSCINP00000029792	Zinc finger protein.	Rabaptin domain-containing protein.	0.408
Ci-ZF(FYVE)-5	H2XUT4_CIOIN	ENSCINP00000008513	ENSCINP00000033418	Zinc finger protein.	Rab5-bind domain-containing protein.	0.408
Ci-ZF(FYVE)-5	H2XZ06_CIOIN	ENSCINP00000008513	ENSCINP00000034890	Zinc finger protein.	Uncharacterized protein.	0.525
Ci-ZF(FYVE)-5	LOC100176004	ENSCINP00000008513	ENSCINP00000029063	Zinc finger protein.	PH domain-containing protein.	0.660
Ci-ZF(FYVE)-5	LOC100180756	ENSCINP00000008513	ENSCINP00000033812	Zinc finger protein.	Ras-related protein RABF2b-like.	0.671
Ci-ZF(FYVE)-5	LOC100182193	ENSCINP00000008513	ENSCINP00000006853	Zinc finger protein.	Ras-related protein Rab-5B.	0.675
Ci-ZF(FYVE)-5	Zf(fyve)-5	ENSCINP00000008513	ENSCINP00000008517	Zinc finger protein.	ANK_REP_REGION domain-containing protein.	0.916
F6PRZ9_CIOIN	F6Q2U2_CIOIN	ENSCINP00000013070	ENSCINP00000013314	Vps8 domain-containing protein.	CNH domain-containing protein.	0.887
F6PRZ9_CIOIN	F6SZ37_CIOIN	ENSCINP00000013070	ENSCINP00000014316	Vps8 domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.995
F6PRZ9_CIOIN	F6WUM1_CIOIN	ENSCINP00000013070	ENSCINP00000007664	Vps8 domain-containing protein.	Uncharacterized protein.	0.512
F6PRZ9_CIOIN	F6YQ60_CIOIN	ENSCINP00000013070	ENSCINP00000011195	Vps8 domain-containing protein.	SAC domain-containing protein.	0.468
F6PRZ9_CIOIN	F6YU56_CIOIN	ENSCINP00000013070	ENSCINP00000026122	Vps8 domain-containing protein.	Uncharacterized protein.	0.937
F6PRZ9_CIOIN	F7BBV8_CIOIN	ENSCINP00000013070	ENSCINP00000011601	Vps8 domain-containing protein.	CNH domain-containing protein.	0.909
F6PRZ9_CIOIN	H2XPJ6_CIOIN	ENSCINP00000013070	ENSCINP00000031580	Vps8 domain-containing protein.	Uncharacterized protein.	0.641
F6PRZ9_CIOIN	H2XX14_CIOIN	ENSCINP00000013070	ENSCINP00000034198	Vps8 domain-containing protein.	Uncharacterized protein.	0.937
F6PRZ9_CIOIN	H2Y130_CIOIN	ENSCINP00000013070	ENSCINP00000035614	Vps8 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.653