(31 nodes) Neurotransmitter-gated ion-channel, and Serotonin receptor activity network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6SU74_CIOIN	Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (774 aa)
	nachr	Uncharacterized protein. (451 aa)
	nachr-2	Nicotinic acetylcholine receptor subunit precursor. (486 aa)
	nachr-3	Uncharacterized protein. (604 aa)
	F6WP04_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (486 aa)
	F6YG13_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (446 aa)
	F6YFX5_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
	F6Z916_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (405 aa)
	LOC100176265	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (456 aa)
	Nachr	Uncharacterized protein. (357 aa)
	nachr-4	Acetylcholine receptor subunit beta-like precursor. (499 aa)
	LOC100181813	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (509 aa)
	ci-glyr	Glycine receptor precursor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (491 aa)
	Nachr-2	Uncharacterized protein. (476 aa)
	nachr-5	Nicotinic acetylcholine receptor subunit precursor. (478 aa)
	Nachr-3	Neur_chan_memb domain-containing protein. (224 aa)
	F6ZFR2_CIOIN	Ion_trans domain-containing protein. (217 aa)
	F6RLD4_CIOIN	Uncharacterized protein. (185 aa)
	F6ZIL3_CIOIN	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (202 aa)
	H2XK29_CIOIN	Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (527 aa)
	H2XLS5_CIOIN	Uncharacterized protein. (203 aa)
	H2XN13_CIOIN	MFS domain-containing protein. (229 aa)
	H2XNE8_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (385 aa)
	H2XQ71_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein. (159 aa)
	H2XRS2_CIOIN	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (657 aa)
	H2XT96_CIOIN	Neur_chan_memb domain-containing protein. (263 aa)
	H2XVB8_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (340 aa)
	Nachr-4	Uncharacterized protein. (774 aa)
	H2XZ12_CIOIN	Uncharacterized protein. (256 aa)
	H2Y0X3_CIOIN	MFS domain-containing protein. (144 aa)
	H2Y1Q0_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (235 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6RLD4_CIOIN	F6YG13_CIOIN	ENSCINP00000025119	ENSCINP00000008772	Uncharacterized protein.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.400
F6RLD4_CIOIN	F6ZIL3_CIOIN	ENSCINP00000025119	ENSCINP00000027830	Uncharacterized protein.	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.417
F6RLD4_CIOIN	H2XT96_CIOIN	ENSCINP00000025119	ENSCINP00000032880	Uncharacterized protein.	Neur_chan_memb domain-containing protein.	0.436
F6RLD4_CIOIN	H2XZ12_CIOIN	ENSCINP00000025119	ENSCINP00000034896	Uncharacterized protein.	Uncharacterized protein.	0.406
F6RLD4_CIOIN	H2Y0X3_CIOIN	ENSCINP00000025119	ENSCINP00000035557	Uncharacterized protein.	MFS domain-containing protein.	0.419
F6RLD4_CIOIN	Nachr-3	ENSCINP00000025119	ENSCINP00000022709	Uncharacterized protein.	Neur_chan_memb domain-containing protein.	0.472
F6RLD4_CIOIN	Nachr-4	ENSCINP00000025119	ENSCINP00000034509	Uncharacterized protein.	Uncharacterized protein.	0.405
F6WP04_CIOIN	F6YG13_CIOIN	ENSCINP00000006703	ENSCINP00000008772	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.401
F6WP04_CIOIN	H2XQ71_CIOIN	ENSCINP00000006703	ENSCINP00000031805	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.411
F6WP04_CIOIN	H2XT96_CIOIN	ENSCINP00000006703	ENSCINP00000032880	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Neur_chan_memb domain-containing protein.	0.439
F6WP04_CIOIN	H2Y0X3_CIOIN	ENSCINP00000006703	ENSCINP00000035557	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	MFS domain-containing protein.	0.441
F6WP04_CIOIN	Nachr-3	ENSCINP00000006703	ENSCINP00000022709	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Neur_chan_memb domain-containing protein.	0.479
F6WP04_CIOIN	nachr-2	ENSCINP00000006703	ENSCINP00000005063	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Nicotinic acetylcholine receptor subunit precursor.	0.444
F6WP04_CIOIN	nachr-3	ENSCINP00000006703	ENSCINP00000006586	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.424
F6WP04_CIOIN	nachr-5	ENSCINP00000006703	ENSCINP00000022560	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Nicotinic acetylcholine receptor subunit precursor.	0.421
F6YFX5_CIOIN	F6YG13_CIOIN	ENSCINP00000008779	ENSCINP00000008772	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.965
F6YFX5_CIOIN	F6Z916_CIOIN	ENSCINP00000008779	ENSCINP00000011153	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.632
F6YFX5_CIOIN	F6ZIL3_CIOIN	ENSCINP00000008779	ENSCINP00000027830	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.573
F6YFX5_CIOIN	H2XNE8_CIOIN	ENSCINP00000008779	ENSCINP00000031181	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.727
F6YFX5_CIOIN	H2XVB8_CIOIN	ENSCINP00000008779	ENSCINP00000033602	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.607