(11 nodes) Mixed, incl. Insulin binding, and CAAX-protein geranylgeranyltransferase complex network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100182889	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (406 aa)
	F6XCJ0_CIOIN	Uncharacterized protein. (289 aa)
	LOC100176674	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (278 aa)
	fta	Uncharacterized protein. (127 aa)
	F6XSL1_CIOIN	Ubiquitin carboxyl-terminal hydrolase. (897 aa)
	F6Q5U4_CIOIN	Uncharacterized protein. (250 aa)
	F6W0A5_CIOIN	Uncharacterized protein. (378 aa)
	F6RX41_CIOIN	Uncharacterized protein. (148 aa)
	LOC100184780	CAAX prenyl protease 2-like. (282 aa)
	H2XQ59_CIOIN	Uncharacterized protein. (57 aa)
	H2Y3R9_CIOIN	Peptidase_M16_M domain-containing protein. (167 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q5U4_CIOIN	H2XQ59_CIOIN	ENSCINP00000018186	ENSCINP00000031793	Uncharacterized protein.	Uncharacterized protein.	0.540
F6Q5U4_CIOIN	fta	ENSCINP00000018186	ENSCINP00000012699	Uncharacterized protein.	Uncharacterized protein.	0.997
F6RX41_CIOIN	LOC100176674	ENSCINP00000022634	ENSCINP00000012053	Uncharacterized protein.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.963
F6RX41_CIOIN	LOC100182889	ENSCINP00000022634	ENSCINP00000011245	Uncharacterized protein.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.642
F6RX41_CIOIN	LOC100184780	ENSCINP00000022634	ENSCINP00000029889	Uncharacterized protein.	CAAX prenyl protease 2-like.	0.966
F6RX41_CIOIN	fta	ENSCINP00000022634	ENSCINP00000012699	Uncharacterized protein.	Uncharacterized protein.	0.642
F6W0A5_CIOIN	F6XCJ0_CIOIN	ENSCINP00000022277	ENSCINP00000011755	Uncharacterized protein.	Uncharacterized protein.	0.927
F6W0A5_CIOIN	F6XSL1_CIOIN	ENSCINP00000022277	ENSCINP00000015942	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.878
F6W0A5_CIOIN	H2Y3R9_CIOIN	ENSCINP00000022277	ENSCINP00000036554	Uncharacterized protein.	Peptidase_M16_M domain-containing protein.	0.944
F6XCJ0_CIOIN	F6W0A5_CIOIN	ENSCINP00000011755	ENSCINP00000022277	Uncharacterized protein.	Uncharacterized protein.	0.927
F6XCJ0_CIOIN	F6XSL1_CIOIN	ENSCINP00000011755	ENSCINP00000015942	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.894
F6XCJ0_CIOIN	H2Y3R9_CIOIN	ENSCINP00000011755	ENSCINP00000036554	Uncharacterized protein.	Peptidase_M16_M domain-containing protein.	0.947
F6XSL1_CIOIN	F6W0A5_CIOIN	ENSCINP00000015942	ENSCINP00000022277	Ubiquitin carboxyl-terminal hydrolase.	Uncharacterized protein.	0.878
F6XSL1_CIOIN	F6XCJ0_CIOIN	ENSCINP00000015942	ENSCINP00000011755	Ubiquitin carboxyl-terminal hydrolase.	Uncharacterized protein.	0.894
H2XQ59_CIOIN	F6Q5U4_CIOIN	ENSCINP00000031793	ENSCINP00000018186	Uncharacterized protein.	Uncharacterized protein.	0.540
H2XQ59_CIOIN	fta	ENSCINP00000031793	ENSCINP00000012699	Uncharacterized protein.	Uncharacterized protein.	0.964
H2Y3R9_CIOIN	F6W0A5_CIOIN	ENSCINP00000036554	ENSCINP00000022277	Peptidase_M16_M domain-containing protein.	Uncharacterized protein.	0.944
H2Y3R9_CIOIN	F6XCJ0_CIOIN	ENSCINP00000036554	ENSCINP00000011755	Peptidase_M16_M domain-containing protein.	Uncharacterized protein.	0.947
LOC100176674	F6RX41_CIOIN	ENSCINP00000012053	ENSCINP00000022634	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Uncharacterized protein.	0.963
LOC100176674	LOC100182889	ENSCINP00000012053	ENSCINP00000011245	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.642