(40 nodes) Aminoglycan biosynthetic process, and HS-GAG biosynthesis network (Ciona intestinalis)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	F6ZZG7_CIOIN	Exostosin domain-containing protein; Belongs to the glycosyltransferase 47 family. (355 aa)
	LOC100177589	Hexosyltransferase. (416 aa)
	F6RCN1_CIOIN	Uncharacterized protein. (115 aa)
	uglcat1	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (340 aa)
	F7BAA5_CIOIN	Uncharacterized protein. (261 aa)
	F7ADM8_CIOIN	Hexosyltransferase. (199 aa)
	xt	Xylosyltransferase; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes; Belongs to the glycosyltransferase 14 family. XylT subfamily. (848 aa)
	LOC100186176	Uronyl 2-sulfotransferase-like. (320 aa)
	F6WFB4_CIOIN	Uncharacterized protein. (809 aa)
	F6RJU6_CIOIN	Uncharacterized protein. (275 aa)
	F6Q0W6_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (753 aa)
	LOC100174990	IF rod domain-containing protein; Belongs to the intermediate filament family. (523 aa)
	F6ZVY0_CIOIN	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (296 aa)
	F7APA8_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (915 aa)
	Not6	Hexosyltransferase. (473 aa)
	LOC100182982	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (382 aa)
	F6PHI7_CIOIN	Hexosyltransferase. (740 aa)
	F7AN36_CIOIN	Hexosyltransferase. (798 aa)
	F6TU56_CIOIN	Uncharacterized protein. (259 aa)
	F7AVD2_CIOIN	Glyco_transf_7C domain-containing protein. (136 aa)
	F6ZQD4_CIOIN	Hexosyltransferase. (695 aa)
	LOC101242339	Sulfotransferase; Belongs to the sulfotransferase 1 family. (432 aa)
	F6TNP4_CIOIN	Uncharacterized protein. (2097 aa)
	LOC100182244	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (438 aa)
	F6S4M7_CIOIN	Uncharacterized protein. (208 aa)
	F6S473_CIOIN	Hexosyltransferase. (741 aa)
	F6Z6T5_CIOIN	Hexosyltransferase. (707 aa)
	F6X117_CIOIN	Hexosyltransferase. (428 aa)
	H2XK55_CIOIN	C5-epim_C domain-containing protein. (572 aa)
	H2XKU8_CIOIN	Sulfotransferase; Belongs to the sulfotransferase 1 family. (322 aa)
	H2XKX6_CIOIN	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (521 aa)
	H2XP09_CIOIN	Uncharacterized protein. (76 aa)
	H2XQM0_CIOIN	Hexosyltransferase. (151 aa)
	b3galt6	Hexosyltransferase. (327 aa)
	H2XVN8_CIOIN	Hexosyltransferase. (216 aa)
	H2XW04_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (660 aa)
	LOC100180531	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (210 aa)
	H2XWZ5_CIOIN	Uncharacterized protein. (346 aa)
	uglcat2l	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (285 aa)
	H2Y2M6_CIOIN	C5-epim_C domain-containing protein. (568 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q0W6_CIOIN	F6WFB4_CIOIN	ENSCINP00000013346	ENSCINP00000012314	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein.	0.633
F6Q0W6_CIOIN	F7AN36_CIOIN	ENSCINP00000013346	ENSCINP00000022686	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Hexosyltransferase.	0.407
F6Q0W6_CIOIN	H2XKU8_CIOIN	ENSCINP00000013346	ENSCINP00000030280	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.481
F6Q0W6_CIOIN	H2XKX6_CIOIN	ENSCINP00000013346	ENSCINP00000030308	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.533
F6Q0W6_CIOIN	H2XW04_CIOIN	ENSCINP00000013346	ENSCINP00000033838	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	0.997
F6Q0W6_CIOIN	H2XWZ5_CIOIN	ENSCINP00000013346	ENSCINP00000034179	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein.	0.547
F6Q0W6_CIOIN	LOC100180531	ENSCINP00000013346	ENSCINP00000034005	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.544
F6Q0W6_CIOIN	LOC100182244	ENSCINP00000013346	ENSCINP00000027821	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.649
F6Q0W6_CIOIN	LOC100182982	ENSCINP00000013346	ENSCINP00000016267	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.531
F6Q0W6_CIOIN	uglcat1	ENSCINP00000013346	ENSCINP00000006544	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.454
F6RCN1_CIOIN	F6RJU6_CIOIN	ENSCINP00000006328	ENSCINP00000013165	Uncharacterized protein.	Uncharacterized protein.	0.941
F6RCN1_CIOIN	H2XP09_CIOIN	ENSCINP00000006328	ENSCINP00000031392	Uncharacterized protein.	Uncharacterized protein.	0.900
F6RCN1_CIOIN	LOC100180531	ENSCINP00000006328	ENSCINP00000034005	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.455
F6RCN1_CIOIN	LOC100186176	ENSCINP00000006328	ENSCINP00000009691	Uncharacterized protein.	Uronyl 2-sulfotransferase-like.	0.909
F6RJU6_CIOIN	F6RCN1_CIOIN	ENSCINP00000013165	ENSCINP00000006328	Uncharacterized protein.	Uncharacterized protein.	0.941
F6RJU6_CIOIN	F6S4M7_CIOIN	ENSCINP00000013165	ENSCINP00000028432	Uncharacterized protein.	Uncharacterized protein.	0.554
F6RJU6_CIOIN	F7BAA5_CIOIN	ENSCINP00000013165	ENSCINP00000006885	Uncharacterized protein.	Uncharacterized protein.	0.540
F6RJU6_CIOIN	H2XP09_CIOIN	ENSCINP00000013165	ENSCINP00000031392	Uncharacterized protein.	Uncharacterized protein.	0.900
F6RJU6_CIOIN	LOC100180531	ENSCINP00000013165	ENSCINP00000034005	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.737
F6RJU6_CIOIN	LOC100182244	ENSCINP00000013165	ENSCINP00000027821	Uncharacterized protein.	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.680