(45 nodes) Protein targeting to mitochondrion, and Processing of SMDT1 network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100183146	Uncharacterized protein. (165 aa)
	LOC100180086	Erythrocyte band 7 integral membrane protein isoform X3. (289 aa)
	LOC104266474	POTRA domain-containing protein. (443 aa)
	F6RNL8_CIOIN	Lon N-terminal domain-containing protein. (331 aa)
	LOC100180734	Mitochondrial import inner membrane translocase subunit Tim22-like. (193 aa)
	F7BAT7_CIOIN	Prohibitin. (271 aa)
	F6UJB5_CIOIN	MCU domain-containing protein. (322 aa)
	LOC100186487	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (431 aa)
	F6XRG3_CIOIN	Prohibitin. (155 aa)
	F7AHK4_CIOIN	AAA domain-containing protein. (618 aa)
	F6YGS0_CIOIN	PHB domain-containing protein. (280 aa)
	F6Y437_CIOIN	Uncharacterized protein. (423 aa)
	LOC100177058	ATP-dependent Clp protease proteolytic subunit. (234 aa)
	F6VAX6_CIOIN	Uncharacterized protein. (405 aa)
	LOC100177909	Iron-sulfur cluster co-chaperone protein HscB, mitochondrial-like isoform X1. (266 aa)
	F6U5X5_CIOIN	Uncharacterized protein. (189 aa)
	F6U5W6_CIOIN	Uncharacterized protein. (368 aa)
	LOC100176696	Poliovirus receptor isoform X2. (605 aa)
	LOC100183112	Mitochondrial intermembrane space import and assembly protein 40-A-like isoform X2. (161 aa)
	F6T949_CIOIN	Peptidase_M41 domain-containing protein. (264 aa)
	LOC100178867	Mitochondrial import receptor subunit TOM40 homolog isoform X1. (338 aa)
	F6WTE3_CIOIN	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (574 aa)
	LOC100181904	Rhomboid protein 1, mitochondrial. (419 aa)
	F6R6J0_CIOIN	Uncharacterized protein. (585 aa)
	F6Z5E6_CIOIN	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (844 aa)
	F6XKQ1_CIOIN	PHB domain-containing protein. (351 aa)
	F6Y8H4_CIOIN	AAA domain-containing protein; Belongs to the AAA ATPase family. (670 aa)
	LOC100180381	Mitochondrial import inner membrane translocase subunit Tim17-B-like. (160 aa)
	LOC100187058	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (215 aa)
	Pax3/7-like	Homeobox domain-containing protein. (301 aa)
	LOC100175733	Metaxin-1-like. (314 aa)
	Zhx1-like	Uncharacterized protein. (662 aa)
	LOC100183218	10 kDa heat shock protein, mitochondrial-like; Belongs to the GroES chaperonin family. (102 aa)
	LOC100187325	Mitochondrial import inner membrane translocase subunit Tim23. (217 aa)
	LOC100178035	Sulfhydryl oxidase. (156 aa)
	H2XT55_CIOIN	Uncharacterized protein. (174 aa)
	LOC100176837	Mitochondrial import inner membrane translocase subunit TIM8; Belongs to the small Tim family. (89 aa)
	H2XU53_CIOIN	Uncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
	H2XU63_CIOIN	Lon proteolytic domain-containing protein. (80 aa)
	H2XWD5_CIOIN	Lon proteolytic domain-containing protein. (82 aa)
	H2XWM7_CIOIN	zf-Tim10_DDP domain-containing protein. (100 aa)
	H2XY09_CIOIN	Uncharacterized protein. (116 aa)
	H2XZJ5_CIOIN	AAA domain-containing protein. (365 aa)
	H2XZW2_CIOIN	zf-Tim10_DDP domain-containing protein. (96 aa)
	H2Y167_CIOIN	Mitochondrial import inner membrane translocase subunit Tim13; Belongs to the small Tim family. (97 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R6J0_CIOIN	F6WTE3_CIOIN	ENSCINP00000018366	ENSCINP00000016022	Uncharacterized protein.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.409
F6R6J0_CIOIN	H2XU53_CIOIN	ENSCINP00000018366	ENSCINP00000033187	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.619
F6R6J0_CIOIN	H2XWM7_CIOIN	ENSCINP00000018366	ENSCINP00000034061	Uncharacterized protein.	zf-Tim10_DDP domain-containing protein.	0.545
F6R6J0_CIOIN	H2XY09_CIOIN	ENSCINP00000018366	ENSCINP00000034543	Uncharacterized protein.	Uncharacterized protein.	0.965
F6R6J0_CIOIN	H2XZW2_CIOIN	ENSCINP00000018366	ENSCINP00000035196	Uncharacterized protein.	zf-Tim10_DDP domain-containing protein.	0.625
F6R6J0_CIOIN	H2Y167_CIOIN	ENSCINP00000018366	ENSCINP00000035651	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit Tim13; Belongs to the small Tim family.	0.511
F6R6J0_CIOIN	LOC100175733	ENSCINP00000018366	ENSCINP00000025217	Uncharacterized protein.	Metaxin-1-like.	0.655
F6R6J0_CIOIN	LOC100176696	ENSCINP00000018366	ENSCINP00000011523	Uncharacterized protein.	Poliovirus receptor isoform X2.	0.865
F6R6J0_CIOIN	LOC100176837	ENSCINP00000018366	ENSCINP00000032972	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit TIM8; Belongs to the small Tim family.	0.556
F6R6J0_CIOIN	LOC100178867	ENSCINP00000018366	ENSCINP00000015646	Uncharacterized protein.	Mitochondrial import receptor subunit TOM40 homolog isoform X1.	0.961
F6R6J0_CIOIN	LOC100180381	ENSCINP00000018366	ENSCINP00000022199	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit Tim17-B-like.	0.644
F6R6J0_CIOIN	LOC100180734	ENSCINP00000018366	ENSCINP00000001694	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit Tim22-like.	0.448
F6R6J0_CIOIN	LOC100183112	ENSCINP00000018366	ENSCINP00000011764	Uncharacterized protein.	Mitochondrial intermembrane space import and assembly protein 40-A-like isoform X2.	0.543
F6R6J0_CIOIN	LOC100183146	ENSCINP00000018366	ENSCINP00000000602	Uncharacterized protein.	Uncharacterized protein.	0.985
F6R6J0_CIOIN	LOC100186487	ENSCINP00000018366	ENSCINP00000004476	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.703
F6R6J0_CIOIN	LOC100187058	ENSCINP00000018366	ENSCINP00000024337	Uncharacterized protein.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.488
F6R6J0_CIOIN	LOC100187325	ENSCINP00000018366	ENSCINP00000030609	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit Tim23.	0.660
F6R6J0_CIOIN	LOC104266474	ENSCINP00000018366	ENSCINP00000001156	Uncharacterized protein.	POTRA domain-containing protein.	0.630
F6RNL8_CIOIN	F6T949_CIOIN	ENSCINP00000001484	ENSCINP00000015464	Lon N-terminal domain-containing protein.	Peptidase_M41 domain-containing protein.	0.430
F6RNL8_CIOIN	F6U5W6_CIOIN	ENSCINP00000001484	ENSCINP00000011297	Lon N-terminal domain-containing protein.	Uncharacterized protein.	0.570