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| | F6WHL2_CIOIN | UmuC domain-containing protein. (288 aa) |
| | F6WGY1_CIOIN | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (246 aa) |
| | F6TSF1_CIOIN | DNA_pol_B domain-containing protein. (217 aa) |
| | Zf(cchc/grf)-1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (456 aa) |
| | F6RJ65_CIOIN | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa) |
| | LOC108950147 | DNA helicase; Belongs to the MCM family. (798 aa) |
| | F6YKR1_CIOIN | DNA_MISMATCH_REPAIR_2 domain-containing protein. (788 aa) |
| | F6VD75_CIOIN | Uncharacterized protein. (553 aa) |
| | F6RZM2_CIOIN | DNA polymerase. (382 aa) |
| | F6RZ99_CIOIN | Zinc-hook domain-containing protein. (477 aa) |
| | F6RYY5_CIOIN | AAA_23 domain-containing protein. (400 aa) |
| | LOC100179498 | DNA repair protein complementing XP-A cells homolog. (279 aa) |
| | LOC100182084 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (461 aa) |
| | F6T6X1_CIOIN | Tudor domain-containing protein. (431 aa) |
| | LOC100179894 | Werner syndrome ATP-dependent helicase homolog isoform X1. (1194 aa) |
| | F6W2K0_CIOIN | DUF1767 domain-containing protein. (486 aa) |
| | LOC100183184 | Uncharacterized protein. (633 aa) |
| | LOC100184693 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa) |
| | F6R4H7_CIOIN | Uncharacterized protein. (315 aa) |
| | LOC100181411 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | F6QHZ5_CIOIN | FHA domain-containing protein. (234 aa) |
| | LOC100182917 | Uncharacterized protein. (127 aa) |
| | LOC100182748 | DNA_mis_repair domain-containing protein. (751 aa) |
| | LOC100185873 | Uncharacterized protein LOC100185873 isoform X1. (181 aa) |
| | LOC100180400 | Uncharacterized protein. (817 aa) |
| | F7AH61_CIOIN | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (283 aa) |
| | F6XMX2_CIOIN | Uncharacterized protein. (279 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (607 aa) |
| | LOC100178968 | DNA polymerase. (1064 aa) |
| | F6QXW9_CIOIN | Helicase ATP-binding domain-containing protein. (273 aa) |
| | F6PPP3_CIOIN | AAA domain-containing protein. (738 aa) |
| | F6PHP1_CIOIN | ENDO3c domain-containing protein. (170 aa) |
| | F6QJE4_CIOIN | Piezo_RRas_bdg domain-containing protein. (188 aa) |
| | F6QJB1_CIOIN | Piezo_RRas_bdg domain-containing protein. (195 aa) |
| | F6QIV0_CIOIN | DNA_pol_E_B domain-containing protein. (328 aa) |
| | F6TBB0_CIOIN | AAA_16 domain-containing protein. (432 aa) |
| | F7BA18_CIOIN | DNA helicase; Belongs to the MCM family. (740 aa) |
| | F6ZUK0_CIOIN | DNA_mis_repair domain-containing protein. (330 aa) |
| | E(spl)/hairy-c | Uncharacterized protein. (522 aa) |
| | F6YH93_CIOIN | Uncharacterized protein. (1111 aa) |
| | F6TV58_CIOIN | Uncharacterized protein. (147 aa) |
| | LOC100182948 | Uncharacterized protein. (219 aa) |
| | LOC100185806 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1250 aa) |
| | LOC100180409 | Meiotic recombination protein SPO11. (385 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (726 aa) |
| | F7ATF3_CIOIN | zf-4CXXC_R1 domain-containing protein. (286 aa) |
| | F6QND3_CIOIN | Mcm10 domain-containing protein. (755 aa) |
| | LOC100175771 | Cell cycle checkpoint control protein; Belongs to the rad9 family. (424 aa) |
| | LOC100181422 | Replication factor C subunit 2-like. (336 aa) |
| | F6WMK2_CIOIN | MCM domain-containing protein; Belongs to the MCM family. (817 aa) |
| | F6WMB2_CIOIN | Uncharacterized protein. (524 aa) |
| | LOC100185652 | Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (530 aa) |
| | F6SK60_CIOIN | Uncharacterized protein. (372 aa) |
| | F6YH10_CIOIN | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (466 aa) |
| | F6UIT3_CIOIN | Uncharacterized protein. (162 aa) |
| | F7B4V9_CIOIN | Replication factor C subunit 1. (866 aa) |
| | LOC100179869 | Checkpoint protein; Belongs to the HUS1 family. (286 aa) |
| | F7BF26_CIOIN | Uncharacterized protein. (449 aa) |
| | F6USX3_CIOIN | Uncharacterized protein. (983 aa) |
| | LOC100181635 | AAA domain-containing protein. (356 aa) |
| | F6Y1Y0_CIOIN | Uncharacterized protein. (217 aa) |
| | F6V4K8_CIOIN | WD_REPEATS_REGION domain-containing protein. (965 aa) |
| | F6UCG0_CIOIN | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (943 aa) |
| | F6PXA9_CIOIN | Uncharacterized protein. (804 aa) |
| | F6RKM9_CIOIN | DNA helicase; Belongs to the MCM family. (820 aa) |
| | LOC100176054 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (436 aa) |
| | LOC100184859 | Replication factor C subunit 3-like. (355 aa) |
| | F6VN25_CIOIN | Uncharacterized protein. (889 aa) |
| | LOC100176493 | AAA domain-containing protein. (844 aa) |
| | LOC100176589 | DNA helicase; Belongs to the MCM family. (785 aa) |
| | LOC100184902 | Geminin. (257 aa) |
| | F6W6L5_CIOIN | MCM domain-containing protein; Belongs to the MCM family. (422 aa) |
| | F6W685_CIOIN | Uncharacterized protein. (428 aa) |
| | LOC100179759 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (820 aa) |
| | F6Z8G0_CIOIN | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (454 aa) |
| | F6W282_CIOIN | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (313 aa) |
| | F6R5V5_CIOIN | Piezo_RRas_bdg domain-containing protein. (539 aa) |
| | LOC100182716 | Flap endonuclease GEN homolog 1. (709 aa) |
| | F6WCV2_CIOIN | Protein kinase domain-containing protein. (510 aa) |
| | F6WC79_CIOIN | Uncharacterized protein. (347 aa) |
| | F6WBW9_CIOIN | DNA_pol_E_B domain-containing protein. (165 aa) |
| | F6Q9T0_CIOIN | Uncharacterized protein. (231 aa) |
| | F6PLC9_CIOIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (128 aa) |
| | F6R213_CIOIN | Uncharacterized protein. (1264 aa) |
| | LOC101242578 | Caltractin. (170 aa) |
| | F6Q9I1_CIOIN | POLAc domain-containing protein. (212 aa) |
| | F6Q9A0_CIOIN | Uncharacterized protein. (157 aa) |
| | F6XHT6_CIOIN | UvrD-like helicase C-terminal domain-containing protein. (212 aa) |
| | F6WUQ7_CIOIN | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2157 aa) |
| | F6QH43_CIOIN | RING-type domain-containing protein. (309 aa) |
| | F7BB99_CIOIN | MUTSd domain-containing protein. (247 aa) |
| | F6UAB2_CIOIN | FANCM-MHF_bd domain-containing protein. (274 aa) |
| | F6TL19_CIOIN | ENDO3c domain-containing protein. (364 aa) |
| | F7BPT5_CIOIN | CBFD_NFYB_HMF domain-containing protein. (75 aa) |
| | LOC100183401 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (426 aa) |
| | F7BEK1_CIOIN | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (219 aa) |
| | F7AWL5_CIOIN | F-box domain-containing protein. (431 aa) |
| | LOC100181040 | D-ribitol-5-phosphate cytidylyltransferase-like isoform X2. (401 aa) |
| | F6U3G5_CIOIN | Uncharacterized protein. (253 aa) |
| | F6V6M0_CIOIN | Uncharacterized protein. (701 aa) |
| | F6YY15_CIOIN | ERCC4 domain-containing protein. (826 aa) |
| | F7BLE6_CIOIN | BHD_3 domain-containing protein. (221 aa) |
| | F7B169_CIOIN | MutL_C domain-containing protein. (252 aa) |
| | F7B162_CIOIN | Uncharacterized protein. (208 aa) |
| | F6Q2W2_CIOIN | ANK_REP_REGION domain-containing protein. (223 aa) |
| | F6RK78_CIOIN | 3'-5' exonuclease domain-containing protein. (291 aa) |
| | F6RK68_CIOIN | Helicase ATP-binding domain-containing protein. (188 aa) |
| | E(spl)/hairy-a | BHLH domain-containing protein. (258 aa) |
| | F6ZKJ6_CIOIN | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (213 aa) |
| | F6T368_CIOIN | DNA_pol_B_exo1 domain-containing protein. (276 aa) |
| | H2XJH5_CIOIN | ANK_REP_REGION domain-containing protein. (95 aa) |
| | LOC113474468 | Replication protein A 14 kDa subunit-like. (118 aa) |
| | H2XJN2_CIOIN | RECA_2 domain-containing protein. (255 aa) |
| | LOC100181596 | Probable nuclear transport factor 2. (137 aa) |
| | H2XKT2_CIOIN | 3'-5' exonuclease domain-containing protein. (128 aa) |
| | H2XKV9_CIOIN | DNA_binding_1 domain-containing protein. (180 aa) |
| | H2XL15_CIOIN | SAE2 domain-containing protein. (153 aa) |
| | H2XL69_CIOIN | Uncharacterized protein. (458 aa) |
| | H2XMH8_CIOIN | BHD_1 domain-containing protein. (362 aa) |
| | LOC100180075 | DNA polymerase delta subunit 4-like isoform X1. (107 aa) |
| | H2XN24_CIOIN | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (158 aa) |
| | H2XN42_CIOIN | Uncharacterized protein. (362 aa) |
| | H2XNL8_CIOIN | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (419 aa) |
| | H2XNP0_CIOIN | Uncharacterized protein. (243 aa) |
| | H2XNU2_CIOIN | Uncharacterized protein. (214 aa) |
| | H2XNU4_CIOIN | Uncharacterized protein. (530 aa) |
| | H2XPE3_CIOIN | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | H2XQ41_CIOIN | UDG domain-containing protein. (250 aa) |
| | H2XQC2_CIOIN | Uncharacterized protein. (257 aa) |
| | H2XQL7_CIOIN | Uncharacterized protein. (295 aa) |
| | H2XR02_CIOIN | DUF1767 domain-containing protein. (229 aa) |
| | H2XRC3_CIOIN | Uncharacterized protein. (224 aa) |
| | H2XRG4_CIOIN | Uncharacterized protein. (1218 aa) |
| | LOC104265697 | Chromosome transmission fidelity protein 8 homolog. (111 aa) |
| | H2XRL5_CIOIN | zf-DNA_Pol domain-containing protein. (143 aa) |
| | cdc45 | Uncharacterized protein. (249 aa) |
| | cbf-2 | Transcription factor CBF/NF-Y/archaeal histone -2. (156 aa) |
| | H2XT98_CIOIN | RECA_2 domain-containing protein. (265 aa) |
| | LOC100181925 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (328 aa) |
| | H2XUA5_CIOIN | Uncharacterized protein. (917 aa) |
| | H2XUG9_CIOIN | Helicase ATP-binding domain-containing protein. (310 aa) |
| | LOC100184078 | CDT1 domain-containing protein. (407 aa) |
| | H2XV49_CIOIN | FAT domain-containing protein. (219 aa) |
| | H2XV86_CIOIN | DNA_MISMATCH_REPAIR_2 domain-containing protein. (290 aa) |
| | H2XVU7_CIOIN | Uncharacterized protein. (125 aa) |
| | H2XWQ0_CIOIN | HELICc2 domain-containing protein. (349 aa) |
| | H2XWS4_CIOIN | Uncharacterized protein. (179 aa) |
| | LOC100176962 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | H2XWY1_CIOIN | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (171 aa) |
| | LOC100182514 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | H2XXZ3_CIOIN | Uncharacterized protein. (870 aa) |
| | LOC100175446 | Uncharacterized protein. (366 aa) |
| | LOC100182896 | DNA replication complex GINS protein PSF1. (195 aa) |
| | H2XZJ6_CIOIN | Uncharacterized protein. (400 aa) |
| | H2XZQ8_CIOIN | Uncharacterized protein. (107 aa) |
| | LOC100179616 | UmuC domain-containing protein. (440 aa) |
| | LOC100179093 | AAA domain-containing protein. (329 aa) |
| | LOC100175682 | DNA polymerase delta subunit 3. (469 aa) |
| | H2Y1H0_CIOIN | Uncharacterized protein. (223 aa) |
| | H2Y1I3_CIOIN | Uncharacterized protein. (231 aa) |
| | H2Y2T2_CIOIN | FAT domain-containing protein. (235 aa) |
| | H2Y2X9_CIOIN | Uncharacterized protein. (137 aa) |
| | H2Y306_CIOIN | Sld5 domain-containing protein. (206 aa) |
| | H2Y334_CIOIN | Uncharacterized protein. (198 aa) |
| | H2Y379_CIOIN | RPA_C domain-containing protein. (133 aa) |
| | LOC100178294 | Uncharacterized protein. (765 aa) |
