STRINGSTRING
LOC108950147 LOC108950147 LOC100182084 LOC100182084 F6R4H7_CIOIN F6R4H7_CIOIN F6TBB0_CIOIN F6TBB0_CIOIN F7BA18_CIOIN F7BA18_CIOIN F6YH93_CIOIN F6YH93_CIOIN MCM7 MCM7 F6QND3_CIOIN F6QND3_CIOIN F6WMK2_CIOIN F6WMK2_CIOIN F6UIT3_CIOIN F6UIT3_CIOIN F6V4K8_CIOIN F6V4K8_CIOIN F6RKM9_CIOIN F6RKM9_CIOIN LOC100176589 LOC100176589 LOC100184902 LOC100184902 F6W6L5_CIOIN F6W6L5_CIOIN F6W685_CIOIN F6W685_CIOIN F6WCV2_CIOIN F6WCV2_CIOIN F6PLC9_CIOIN F6PLC9_CIOIN LOC100183401 LOC100183401 F7BEK1_CIOIN F7BEK1_CIOIN H2XNL8_CIOIN H2XNL8_CIOIN H2XPE3_CIOIN H2XPE3_CIOIN cdc45 cdc45 LOC100184078 LOC100184078 LOC100182896 LOC100182896 H2Y306_CIOIN H2Y306_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108950147DNA helicase; Belongs to the MCM family. (798 aa)
LOC100182084Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (461 aa)
F6R4H7_CIOINUncharacterized protein. (315 aa)
F6TBB0_CIOINAAA_16 domain-containing protein. (432 aa)
F7BA18_CIOINDNA helicase; Belongs to the MCM family. (740 aa)
F6YH93_CIOINUncharacterized protein. (1111 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (726 aa)
F6QND3_CIOINMcm10 domain-containing protein. (755 aa)
F6WMK2_CIOINMCM domain-containing protein; Belongs to the MCM family. (817 aa)
F6UIT3_CIOINUncharacterized protein. (162 aa)
F6V4K8_CIOINWD_REPEATS_REGION domain-containing protein. (965 aa)
F6RKM9_CIOINDNA helicase; Belongs to the MCM family. (820 aa)
LOC100176589DNA helicase; Belongs to the MCM family. (785 aa)
LOC100184902Geminin. (257 aa)
F6W6L5_CIOINMCM domain-containing protein; Belongs to the MCM family. (422 aa)
F6W685_CIOINUncharacterized protein. (428 aa)
F6WCV2_CIOINProtein kinase domain-containing protein. (510 aa)
F6PLC9_CIOINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (128 aa)
LOC100183401Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (426 aa)
F7BEK1_CIOINDNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (219 aa)
H2XNL8_CIOINOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (419 aa)
H2XPE3_CIOINDNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
cdc45Uncharacterized protein. (249 aa)
LOC100184078CDT1 domain-containing protein. (407 aa)
LOC100182896DNA replication complex GINS protein PSF1. (195 aa)
H2Y306_CIOINSld5 domain-containing protein. (206 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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