(28 nodes) HDR through Single Strand Annealing (SSA), and Helicase superfamily 1/2, DinG/Rad3-like network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6RJ65_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
	F6RZ99_CIOIN	Zinc-hook domain-containing protein. (477 aa)
	F6RYY5_CIOIN	AAA_23 domain-containing protein. (400 aa)
	F6QHZ5_CIOIN	FHA domain-containing protein. (234 aa)
	F6XMX2_CIOIN	Uncharacterized protein. (279 aa)
	F6TV58_CIOIN	Uncharacterized protein. (147 aa)
	F7ATF3_CIOIN	zf-4CXXC_R1 domain-containing protein. (286 aa)
	LOC100175771	Cell cycle checkpoint control protein; Belongs to the rad9 family. (424 aa)
	F6WMB2_CIOIN	Uncharacterized protein. (524 aa)
	LOC100185652	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (530 aa)
	LOC100179869	Checkpoint protein; Belongs to the HUS1 family. (286 aa)
	F6VN25_CIOIN	Uncharacterized protein. (889 aa)
	F6Z8G0_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (454 aa)
	F6WC79_CIOIN	Uncharacterized protein. (347 aa)
	F6QH43_CIOIN	RING-type domain-containing protein. (309 aa)
	F6Q2W2_CIOIN	ANK_REP_REGION domain-containing protein. (223 aa)
	H2XJH5_CIOIN	ANK_REP_REGION domain-containing protein. (95 aa)
	H2XL15_CIOIN	SAE2 domain-containing protein. (153 aa)
	H2XL69_CIOIN	Uncharacterized protein. (458 aa)
	H2XN24_CIOIN	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (158 aa)
	H2XNP0_CIOIN	Uncharacterized protein. (243 aa)
	H2XNU2_CIOIN	Uncharacterized protein. (214 aa)
	H2XNU4_CIOIN	Uncharacterized protein. (530 aa)
	H2XRC3_CIOIN	Uncharacterized protein. (224 aa)
	H2XUG9_CIOIN	Helicase ATP-binding domain-containing protein. (310 aa)
	H2XV49_CIOIN	FAT domain-containing protein. (219 aa)
	H2XWQ0_CIOIN	HELICc2 domain-containing protein. (349 aa)
	H2Y2T2_CIOIN	FAT domain-containing protein. (235 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q2W2_CIOIN	F6QH43_CIOIN	ENSCINP00000025008	ENSCINP00000020173	ANK_REP_REGION domain-containing protein.	RING-type domain-containing protein.	0.972
F6Q2W2_CIOIN	F6QHZ5_CIOIN	ENSCINP00000025008	ENSCINP00000004918	ANK_REP_REGION domain-containing protein.	FHA domain-containing protein.	0.875
F6Q2W2_CIOIN	F6RJ65_CIOIN	ENSCINP00000025008	ENSCINP00000001490	ANK_REP_REGION domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.494
F6Q2W2_CIOIN	F6RYY5_CIOIN	ENSCINP00000025008	ENSCINP00000003245	ANK_REP_REGION domain-containing protein.	AAA_23 domain-containing protein.	0.615
F6Q2W2_CIOIN	F6RZ99_CIOIN	ENSCINP00000025008	ENSCINP00000003235	ANK_REP_REGION domain-containing protein.	Zinc-hook domain-containing protein.	0.615
F6Q2W2_CIOIN	F6WC79_CIOIN	ENSCINP00000025008	ENSCINP00000017779	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.455
F6Q2W2_CIOIN	F6WMB2_CIOIN	ENSCINP00000025008	ENSCINP00000010261	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.584
F6Q2W2_CIOIN	F6XMX2_CIOIN	ENSCINP00000025008	ENSCINP00000005706	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.459
F6Q2W2_CIOIN	F6Z8G0_CIOIN	ENSCINP00000025008	ENSCINP00000016265	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.442
F6Q2W2_CIOIN	H2XL15_CIOIN	ENSCINP00000025008	ENSCINP00000030347	ANK_REP_REGION domain-containing protein.	SAE2 domain-containing protein.	0.945
F6Q2W2_CIOIN	H2XL69_CIOIN	ENSCINP00000025008	ENSCINP00000030401	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.475
F6Q2W2_CIOIN	H2XNU2_CIOIN	ENSCINP00000025008	ENSCINP00000031325	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.615
F6Q2W2_CIOIN	H2XUG9_CIOIN	ENSCINP00000025008	ENSCINP00000033303	ANK_REP_REGION domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.662
F6Q2W2_CIOIN	H2XWQ0_CIOIN	ENSCINP00000025008	ENSCINP00000034084	ANK_REP_REGION domain-containing protein.	HELICc2 domain-containing protein.	0.662
F6Q2W2_CIOIN	H2Y2T2_CIOIN	ENSCINP00000025008	ENSCINP00000036217	ANK_REP_REGION domain-containing protein.	FAT domain-containing protein.	0.494
F6Q2W2_CIOIN	LOC100175771	ENSCINP00000025008	ENSCINP00000010009	ANK_REP_REGION domain-containing protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.432
F6Q2W2_CIOIN	LOC100179869	ENSCINP00000025008	ENSCINP00000011013	ANK_REP_REGION domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.464
F6Q2W2_CIOIN	LOC100185652	ENSCINP00000025008	ENSCINP00000010283	ANK_REP_REGION domain-containing protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.887
F6QH43_CIOIN	F6Q2W2_CIOIN	ENSCINP00000020173	ENSCINP00000025008	RING-type domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.972
F6QH43_CIOIN	F6QHZ5_CIOIN	ENSCINP00000020173	ENSCINP00000004918	RING-type domain-containing protein.	FHA domain-containing protein.	0.838