(16 nodes) Mixed, incl. Degradation of GABA, and acetate-CoA ligase activity network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6Q7A6_CIOIN	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (475 aa)
	F6SUM0_CIOIN	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (501 aa)
	F7AAH8_CIOIN	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (502 aa)
	LOC100181599	Acylphosphatase. (108 aa)
	F6S360_CIOIN	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (388 aa)
	LOC100181655	Aldedh domain-containing protein. (530 aa)
	LOC100178943	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (327 aa)
	LOC100182755	Aldehyde dehydrogenase family 16 member A1-like; Belongs to the aldehyde dehydrogenase family. (827 aa)
	F6THC9_CIOIN	Uncharacterized protein. (537 aa)
	LOC100177936	Uncharacterized protein. (707 aa)
	F7B0S6_CIOIN	Acetyl-coenzyme A synthetase. (667 aa)
	F6WXA3_CIOIN	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (473 aa)
	LOC100180018	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)
	H2XY01_CIOIN	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (466 aa)
	H2XYB0_CIOIN	Uncharacterized protein. (664 aa)
	H2XYN5_CIOIN	Acetyl-coenzyme A synthetase. (633 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q7A6_CIOIN	F6SUM0_CIOIN	ENSCINP00000001020	ENSCINP00000004184	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.945
F6Q7A6_CIOIN	F6THC9_CIOIN	ENSCINP00000001020	ENSCINP00000016122	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.820
F6Q7A6_CIOIN	F7AAH8_CIOIN	ENSCINP00000001020	ENSCINP00000004225	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.945
F6Q7A6_CIOIN	F7B0S6_CIOIN	ENSCINP00000001020	ENSCINP00000017977	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase.	0.954
F6Q7A6_CIOIN	H2XY01_CIOIN	ENSCINP00000001020	ENSCINP00000034535	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.903
F6Q7A6_CIOIN	H2XYB0_CIOIN	ENSCINP00000001020	ENSCINP00000034644	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.909
F6Q7A6_CIOIN	H2XYN5_CIOIN	ENSCINP00000001020	ENSCINP00000034769	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase.	0.954
F6Q7A6_CIOIN	LOC100177936	ENSCINP00000001020	ENSCINP00000016533	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.814
F6Q7A6_CIOIN	LOC100178943	ENSCINP00000001020	ENSCINP00000012462	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.926
F6Q7A6_CIOIN	LOC100181599	ENSCINP00000001020	ENSCINP00000004434	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acylphosphatase.	0.902
F6Q7A6_CIOIN	LOC100181655	ENSCINP00000001020	ENSCINP00000011962	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein.	0.926
F6Q7A6_CIOIN	LOC100182755	ENSCINP00000001020	ENSCINP00000013324	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase family 16 member A1-like; Belongs to the aldehyde dehydrogenase family.	0.908
F6S360_CIOIN	F6THC9_CIOIN	ENSCINP00000006553	ENSCINP00000016122	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.489
F6S360_CIOIN	F7B0S6_CIOIN	ENSCINP00000006553	ENSCINP00000017977	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-coenzyme A synthetase.	0.419
F6S360_CIOIN	H2XYB0_CIOIN	ENSCINP00000006553	ENSCINP00000034644	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.417
F6S360_CIOIN	H2XYN5_CIOIN	ENSCINP00000006553	ENSCINP00000034769	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-coenzyme A synthetase.	0.417
F6S360_CIOIN	LOC100177936	ENSCINP00000006553	ENSCINP00000016533	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.463
F6S360_CIOIN	LOC100178943	ENSCINP00000006553	ENSCINP00000012462	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.997
F6S360_CIOIN	LOC100181655	ENSCINP00000006553	ENSCINP00000011962	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Aldedh domain-containing protein.	0.718
F6SUM0_CIOIN	F6Q7A6_CIOIN	ENSCINP00000004184	ENSCINP00000001020	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.945