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F6YIX5_CIOIN F6YIX5_CIOIN LOC100184016 LOC100184016 F7BBJ9_CIOIN F7BBJ9_CIOIN LOC100174998 LOC100174998 LOC100179315 LOC100179315 F6SI53_CIOIN F6SI53_CIOIN F6YNQ3_CIOIN F6YNQ3_CIOIN F6UTV1_CIOIN F6UTV1_CIOIN F6V7M4_CIOIN F6V7M4_CIOIN F6UHA9_CIOIN F6UHA9_CIOIN LOC100184477 LOC100184477 LOC100177066 LOC100177066 F7AZV0_CIOIN F7AZV0_CIOIN LOC100181830 LOC100181830 F6SUS9_CIOIN F6SUS9_CIOIN LOC100184967 LOC100184967 LOC100186950 LOC100186950 LOC100181512 LOC100181512 LOC100175858 LOC100175858 F6WR85_CIOIN F6WR85_CIOIN F6Z761_CIOIN F6Z761_CIOIN F6YME4_CIOIN F6YME4_CIOIN LOC100184965 LOC100184965 F6ZF70_CIOIN F6ZF70_CIOIN LOC100178529 LOC100178529 F6PL99_CIOIN F6PL99_CIOIN F6PL95_CIOIN F6PL95_CIOIN LOC100180725 LOC100180725 LOC100186938 LOC100186938 F6U5F1_CIOIN F6U5F1_CIOIN F7BH52_CIOIN F7BH52_CIOIN F6VGB1_CIOIN F6VGB1_CIOIN H2XM65_CIOIN H2XM65_CIOIN H2XN84_CIOIN H2XN84_CIOIN Acl Acl H2XU13_CIOIN H2XU13_CIOIN LOC100186045 LOC100186045 H2XYI4_CIOIN H2XYI4_CIOIN H2Y297_CIOIN H2Y297_CIOIN LOC100180707 LOC100180707 H2Y3K9_CIOIN H2Y3K9_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6YIX5_CIOINDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (476 aa)
LOC100184016Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
F7BBJ9_CIOINPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (357 aa)
LOC100174998L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (341 aa)
LOC100179315Aspartate aminotransferase. (425 aa)
F6SI53_CIOINSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (516 aa)
F6YNQ3_CIOINIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (353 aa)
F6UTV1_CIOINSuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (337 aa)
F6V7M4_CIOINTransket_pyr domain-containing protein. (156 aa)
F6UHA9_CIOIN2-oxogl_dehyd_N domain-containing protein. (264 aa)
LOC100184477Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (385 aa)
LOC100177066Uncharacterized protein. (641 aa)
F7AZV0_CIOINLipoyl-binding domain-containing protein. (391 aa)
LOC100181830Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
F6SUS9_CIOINIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (370 aa)
LOC100184967Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (432 aa)
LOC100186950Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial-like. (398 aa)
LOC100181512Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1186 aa)
LOC100175858Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (452 aa)
F6WR85_CIOINDihydrolipoyl dehydrogenase. (509 aa)
F6Z761_CIOINUncharacterized protein. (470 aa)
F6YME4_CIOINUncharacterized protein. (83 aa)
LOC100184965Aspartate aminotransferase. (415 aa)
F6ZF70_CIOINIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (422 aa)
LOC100178529Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily. (345 aa)
F6PL99_CIOINAconitase domain-containing protein. (347 aa)
F6PL95_CIOINUncharacterized protein. (418 aa)
LOC100180725Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (166 aa)
LOC100186938Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (892 aa)
F6U5F1_CIOINLigase_CoA domain-containing protein. (404 aa)
F7BH52_CIOINAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (508 aa)
F6VGB1_CIOINUncharacterized protein; Belongs to the LDH/MDH superfamily. (359 aa)
H2XM65_CIOINUncharacterized protein. (105 aa)
H2XN84_CIOINFAD_binding_2 domain-containing protein. (152 aa)
AclATP-grasp_2 domain-containing protein. (250 aa)
H2XU13_CIOINCitrate synthase; Belongs to the citrate synthase family. (469 aa)
LOC100186045FAD-binding PCMH-type domain-containing protein. (470 aa)
H2XYI4_CIOINCitrate_bind domain-containing protein. (84 aa)
H2Y297_CIOINOxoGdeHyase_C domain-containing protein. (52 aa)
LOC100180707Omega-amidase NIT2. (302 aa)
H2Y3K9_CIOINMalate dehydrogenase. (334 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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