node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F6UHA9_CIOIN | F6UTV1_CIOIN | ENSCINP00000012074 | ENSCINP00000011271 | 2-oxogl_dehyd_N domain-containing protein. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.975 |
F6UHA9_CIOIN | F6V7M4_CIOIN | ENSCINP00000012074 | ENSCINP00000012048 | 2-oxogl_dehyd_N domain-containing protein. | Transket_pyr domain-containing protein. | 0.973 |
F6UHA9_CIOIN | F6WR85_CIOIN | ENSCINP00000012074 | ENSCINP00000016324 | 2-oxogl_dehyd_N domain-containing protein. | Dihydrolipoyl dehydrogenase. | 0.998 |
F6UHA9_CIOIN | F6YIX5_CIOIN | ENSCINP00000012074 | ENSCINP00000003336 | 2-oxogl_dehyd_N domain-containing protein. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.875 |
F6UHA9_CIOIN | F7AZV0_CIOIN | ENSCINP00000012074 | ENSCINP00000014023 | 2-oxogl_dehyd_N domain-containing protein. | Lipoyl-binding domain-containing protein. | 0.999 |
F6UHA9_CIOIN | F7BBJ9_CIOIN | ENSCINP00000012074 | ENSCINP00000006593 | 2-oxogl_dehyd_N domain-containing protein. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.876 |
F6UHA9_CIOIN | F7BH52_CIOIN | ENSCINP00000012074 | ENSCINP00000026648 | 2-oxogl_dehyd_N domain-containing protein. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.875 |
F6UHA9_CIOIN | LOC100175858 | ENSCINP00000012074 | ENSCINP00000015522 | 2-oxogl_dehyd_N domain-containing protein. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.940 |
F6UHA9_CIOIN | LOC100184477 | ENSCINP00000012074 | ENSCINP00000012352 | 2-oxogl_dehyd_N domain-containing protein. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.892 |
F6UHA9_CIOIN | LOC100184967 | ENSCINP00000012074 | ENSCINP00000015047 | 2-oxogl_dehyd_N domain-containing protein. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.862 |
F6UTV1_CIOIN | F6UHA9_CIOIN | ENSCINP00000011271 | ENSCINP00000012074 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 2-oxogl_dehyd_N domain-containing protein. | 0.975 |
F6UTV1_CIOIN | F6V7M4_CIOIN | ENSCINP00000011271 | ENSCINP00000012048 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Transket_pyr domain-containing protein. | 0.969 |
F6UTV1_CIOIN | F6WR85_CIOIN | ENSCINP00000011271 | ENSCINP00000016324 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Dihydrolipoyl dehydrogenase. | 0.939 |
F6UTV1_CIOIN | F6YIX5_CIOIN | ENSCINP00000011271 | ENSCINP00000003336 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.906 |
F6UTV1_CIOIN | F7AZV0_CIOIN | ENSCINP00000011271 | ENSCINP00000014023 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Lipoyl-binding domain-containing protein. | 0.993 |
F6UTV1_CIOIN | F7BBJ9_CIOIN | ENSCINP00000011271 | ENSCINP00000006593 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.753 |
F6UTV1_CIOIN | F7BH52_CIOIN | ENSCINP00000011271 | ENSCINP00000026648 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.906 |
F6UTV1_CIOIN | LOC100175858 | ENSCINP00000011271 | ENSCINP00000015522 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |
F6UTV1_CIOIN | LOC100184477 | ENSCINP00000011271 | ENSCINP00000012352 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.643 |
F6UTV1_CIOIN | LOC100184967 | ENSCINP00000011271 | ENSCINP00000015047 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |