STRINGSTRING
LOC100180412 LOC100180412 LOC100182393 LOC100182393 F6YIX1_CIOIN F6YIX1_CIOIN F6WIH5_CIOIN F6WIH5_CIOIN LOC100186125 LOC100186125 F6WST8_CIOIN F6WST8_CIOIN LOC100183973 LOC100183973 F6X139_CIOIN F6X139_CIOIN Selo Selo F6ZYQ8_CIOIN F6ZYQ8_CIOIN per-like per-like F6UAZ6_CIOIN F6UAZ6_CIOIN LOC100175075 LOC100175075 LOC100177321 LOC100177321 F6U899_CIOIN F6U899_CIOIN F6V6V3_CIOIN F6V6V3_CIOIN LOC100182293 LOC100182293 F6TTJ7_CIOIN F6TTJ7_CIOIN LOC100178161 LOC100178161 F7AUL7_CIOIN F7AUL7_CIOIN F7B7H5_CIOIN F7B7H5_CIOIN F6Z0U7_CIOIN F6Z0U7_CIOIN F7AVN1_CIOIN F7AVN1_CIOIN F7B1W8_CIOIN F7B1W8_CIOIN LOC100180659 LOC100180659 Sepn1 Sepn1 LOC100179351 LOC100179351 LOC100176001 LOC100176001 LOC100179970 LOC100179970 LOC100183606 LOC100183606 F7APB5_CIOIN F7APB5_CIOIN F7A1S8_CIOIN F7A1S8_CIOIN LOC100177365 LOC100177365 F6SCU4_CIOIN F6SCU4_CIOIN F6UUA2_CIOIN F6UUA2_CIOIN LOC100183957 LOC100183957 LOC100184460 LOC100184460 F6VMC6_CIOIN F6VMC6_CIOIN LOC100176864 LOC100176864 F7BF63_CIOIN F7BF63_CIOIN F6X7G6_CIOIN F6X7G6_CIOIN F6TGA3_CIOIN F6TGA3_CIOIN F6TG38_CIOIN F6TG38_CIOIN LOC100175914 LOC100175914 F7AK54_CIOIN F7AK54_CIOIN H2XLH0_CIOIN H2XLH0_CIOIN H2XLX4_CIOIN H2XLX4_CIOIN H2XM96_CIOIN H2XM96_CIOIN H2XME2_CIOIN H2XME2_CIOIN sep15 sep15 H2XNB1_CIOIN H2XNB1_CIOIN LOC101243380 LOC101243380 H2XPC7_CIOIN H2XPC7_CIOIN LOC100184069 LOC100184069 H2XSD2_CIOIN H2XSD2_CIOIN LOC100181245 LOC100181245 H2XTM9_CIOIN H2XTM9_CIOIN H2XTT8_CIOIN H2XTT8_CIOIN LOC100175802 LOC100175802 selk selk H2XUG5_CIOIN H2XUG5_CIOIN Sels Sels H2XVX4_CIOIN H2XVX4_CIOIN LOC100180651 LOC100180651 H2XXS6_CIOIN H2XXS6_CIOIN LOC100181030 LOC100181030 H2XXW3_CIOIN H2XXW3_CIOIN H2XYU7_CIOIN H2XYU7_CIOIN H2XZE7_CIOIN H2XZE7_CIOIN LOC100178002 LOC100178002 gpx_d gpx_d Txnrd3 Txnrd3 LOC100183896 LOC100183896
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC100180412Rhodanese domain-containing protein. (143 aa)
LOC100182393Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (322 aa)
F6YIX1_CIOINUncharacterized protein. (138 aa)
F6WIH5_CIOINSulfiredoxin. (119 aa)
LOC100186125Glutaredoxin-3. (330 aa)
F6WST8_CIOINGlutaredoxin domain-containing protein. (487 aa)
LOC100183973Cytochrome b5 isoform X1; Belongs to the cytochrome b5 family. (132 aa)
F6X139_CIOINLactamase_B domain-containing protein. (238 aa)
SeloUncharacterized protein. (637 aa)
F6ZYQ8_CIOINMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (211 aa)
per-likePeroxiredoxin-like. (197 aa)
F6UAZ6_CIOINFe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (477 aa)
LOC100175075Cytosolic Fe-S cluster assembly factor NUBP2 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (262 aa)
LOC100177321Uncharacterized protein. (220 aa)
F6U899_CIOINDJ-1_PfpI domain-containing protein. (187 aa)
F6V6V3_CIOINMOSC domain-containing protein. (52 aa)
LOC100182293Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (217 aa)
F6TTJ7_CIOINMOSC domain-containing protein. (643 aa)
LOC100178161O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (495 aa)
F7AUL7_CIOINUncharacterized protein. (989 aa)
F7B7H5_CIOINCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (521 aa)
F6Z0U7_CIOINUncharacterized protein. (131 aa)
F7AVN1_CIOINLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (358 aa)
F7B1W8_CIOINNfu_N domain-containing protein. (193 aa)
LOC100180659Probable thioredoxin-2. (175 aa)
Sepn1EF-hand domain-containing protein. (463 aa)
LOC100179351NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family. (601 aa)
LOC100176001Cytochrome b5 domain-containing protein 1-like; Belongs to the cytochrome b5 family. (217 aa)
LOC100179970Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (337 aa)
LOC100183606Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (147 aa)
F7APB5_CIOINUncharacterized protein. (382 aa)
F7A1S8_CIOINAdenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] (410 aa)
LOC100177365MIP18 family protein galla-2-like. (166 aa)
F6SCU4_CIOINAminotran_5 domain-containing protein. (219 aa)
F6UUA2_CIOINAminotran_5 domain-containing protein. (414 aa)
LOC100183957Thioredoxin; Belongs to the thioredoxin family. (107 aa)
LOC100184460Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (157 aa)
F6VMC6_CIOINBPL/LPL catalytic domain-containing protein. (303 aa)
LOC100176864Glyoxalase domain-containing protein 4-like isoform X2. (296 aa)
F7BF63_CIOINAminotran_5 domain-containing protein. (136 aa)
F6X7G6_CIOINLactamase_B domain-containing protein. (153 aa)
F6TGA3_CIOINUncharacterized protein. (561 aa)
F6TG38_CIOINUncharacterized protein. (582 aa)
LOC100175914Sulfide:quinone oxidoreductase, mitochondrial. (440 aa)
F7AK54_CIOINGlutaredoxin domain-containing protein. (100 aa)
H2XLH0_CIOINPutative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. (241 aa)
H2XLX4_CIOINNfu_N domain-containing protein. (258 aa)
H2XM96_CIOINAldo_ket_red domain-containing protein. (261 aa)
H2XME2_CIOINAnamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (298 aa)
sep15Uncharacterized protein. (92 aa)
H2XNB1_CIOINElp3 domain-containing protein. (583 aa)
LOC101243380Uncharacterized protein LOC101243380; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (155 aa)
H2XPC7_CIOINUncharacterized protein. (175 aa)
LOC100184069Cytosolic iron-sulfur assembly component 2A isoform X1. (128 aa)
H2XSD2_CIOINRibosomal_L7Ae domain-containing protein. (1004 aa)
LOC100181245Glutaredoxin-like. (107 aa)
H2XTM9_CIOINATP-cone domain-containing protein. (31 aa)
H2XTT8_CIOINUncharacterized protein; Belongs to the BolA/IbaG family. (89 aa)
LOC100175802Peroxiredoxin-like. (235 aa)
selkUncharacterized protein. (89 aa)
H2XUG5_CIOINUncharacterized protein. (826 aa)
SelsUncharacterized protein. (202 aa)
H2XVX4_CIOINCytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (185 aa)
LOC100180651Rhodanese domain-containing protein CG4456-like isoform X1. (126 aa)
H2XXS6_CIOINMoCF_biosynth domain-containing protein. (151 aa)
LOC100181030Thioredoxin; Belongs to the thioredoxin family. (106 aa)
H2XXW3_CIOINUncharacterized protein. (851 aa)
H2XYU7_CIOINUncharacterized protein. (265 aa)
H2XZE7_CIOINGlutaredoxin domain-containing protein. (133 aa)
LOC100178002Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (377 aa)
gpx_dGlutathione peroxidase; Belongs to the glutathione peroxidase family. (165 aa)
Txnrd3Glutaredoxin domain-containing protein. (596 aa)
LOC100183896Iron-sulfur cluster assembly 2 homolog, mitochondrial-like. (154 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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