STRINGSTRING
F6ZI65_CIOIN F6ZI65_CIOIN F6WDZ2_CIOIN F6WDZ2_CIOIN F7BL51_CIOIN F7BL51_CIOIN Sir2-d Sir2-d LOC100185313 LOC100185313 F6UM48_CIOIN F6UM48_CIOIN LOC100187498 LOC100187498 F6WSV9_CIOIN F6WSV9_CIOIN LOC100181727 LOC100181727 F6TEA7_CIOIN F6TEA7_CIOIN F6SSJ7_CIOIN F6SSJ7_CIOIN LOC100178591 LOC100178591 LOC100181977 LOC100181977 F6WZU2_CIOIN F6WZU2_CIOIN LOC100181600 LOC100181600 F6QJB5_CIOIN F6QJB5_CIOIN F6Y8R5_CIOIN F6Y8R5_CIOIN LOC100186604 LOC100186604 F6TKE5_CIOIN F6TKE5_CIOIN LOC100181027 LOC100181027 pdedelta pdedelta F6SKP5_CIOIN F6SKP5_CIOIN LOC100178564 LOC100178564 LOC100186749 LOC100186749 ci-ak58 ci-ak58 F6YNT4_CIOIN F6YNT4_CIOIN LOC100175447 LOC100175447 LOC100182043 LOC100182043 F6TAK8_CIOIN F6TAK8_CIOIN F7BQ75_CIOIN F7BQ75_CIOIN LOC100181174 LOC100181174 F6YQS6_CIOIN F6YQS6_CIOIN F7BBQ5_CIOIN F7BBQ5_CIOIN F7A9J1_CIOIN F7A9J1_CIOIN LOC100185509 LOC100185509 LOC100176897 LOC100176897 LOC100185251-2 LOC100185251-2 LOC100177271 LOC100177271 LOC100179541 LOC100179541 F6Q548_CIOIN F6Q548_CIOIN F6QW33_CIOIN F6QW33_CIOIN LOC100182436 LOC100182436 F6U053_CIOIN F6U053_CIOIN LOC100182227 LOC100182227 LOC100183100 LOC100183100 F6VKX1_CIOIN F6VKX1_CIOIN LOC100183021 LOC100183021 F6SJ18_CIOIN F6SJ18_CIOIN F6Z6J2_CIOIN F6Z6J2_CIOIN LOC100177202 LOC100177202 F6YD09_CIOIN F6YD09_CIOIN F6T1L5_CIOIN F6T1L5_CIOIN F7BJC2_CIOIN F7BJC2_CIOIN F6QF37_CIOIN F6QF37_CIOIN LOC100177393 LOC100177393 F6WWW9_CIOIN F6WWW9_CIOIN F6TK42_CIOIN F6TK42_CIOIN LOC100178005 LOC100178005 F6XHJ8_CIOIN F6XHJ8_CIOIN F7B963_CIOIN F7B963_CIOIN F7APS6_CIOIN F7APS6_CIOIN LOC113474072 LOC113474072 LOC100185848 LOC100185848 F6USH9_CIOIN F6USH9_CIOIN F6USG9_CIOIN F6USG9_CIOIN LOC100186893 LOC100186893 F7ASW5_CIOIN F7ASW5_CIOIN F6ZQL1_CIOIN F6ZQL1_CIOIN LOC100178048 LOC100178048 F6TT30_CIOIN F6TT30_CIOIN ci-ndk/dm44 ci-ndk/dm44 LOC100180887 LOC100180887 F6ZC01_CIOIN F6ZC01_CIOIN LOC100175348 LOC100175348 F6YSG2_CIOIN F6YSG2_CIOIN F7A5R9_CIOIN F7A5R9_CIOIN LOC778889 LOC778889 F6SLD6_CIOIN F6SLD6_CIOIN F6PJS6_CIOIN F6PJS6_CIOIN LOC100183847 LOC100183847 LOC100187016 LOC100187016 H2XMC4_CIOIN H2XMC4_CIOIN LOC100184518 LOC100184518 H2XPZ0_CIOIN H2XPZ0_CIOIN H2XQZ0_CIOIN H2XQZ0_CIOIN H2XT70_CIOIN H2XT70_CIOIN H2XV35_CIOIN H2XV35_CIOIN sir2-a sir2-a H2XWF2_CIOIN H2XWF2_CIOIN H2XZK6_CIOIN H2XZK6_CIOIN H2Y002_CIOIN H2Y002_CIOIN LOC100186031 LOC100186031 H2Y0K0_CIOIN H2Y0K0_CIOIN H2Y0S2_CIOIN H2Y0S2_CIOIN H2Y207_CIOIN H2Y207_CIOIN H2Y237_CIOIN H2Y237_CIOIN H2Y3J4_CIOIN H2Y3J4_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6ZI65_CIOINIU_nuc_hydro domain-containing protein. (338 aa)
F6WDZ2_CIOINRIBORED_LARGE domain-containing protein. (193 aa)
F7BL51_CIOINAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (487 aa)
Sir2-dDeacetylase sirtuin-type domain-containing protein. (91 aa)
LOC100185313Isochorismatase domain-containing protein 1-like. (270 aa)
F6UM48_CIOINUncharacterized protein. (1861 aa)
LOC100187498Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (624 aa)
F6WSV9_CIOINA_deaminase domain-containing protein. (361 aa)
LOC100181727Uncharacterized protein. (337 aa)
F6TEA7_CIOINGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (587 aa)
F6SSJ7_CIOINIsochorismatase domain-containing protein. (116 aa)
LOC100178591Guanylate cyclase soluble subunit alpha-2 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (518 aa)
LOC100181977Uncharacterized protein. (232 aa)
F6WZU2_CIOINdNK domain-containing protein. (265 aa)
LOC100181600Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)
F6QJB5_CIOINHD domain-containing protein. (179 aa)
F6Y8R5_CIOINGAF domain-containing protein. (216 aa)
LOC100186604Uridine-cytidine kinase; Belongs to the uridine kinase family. (505 aa)
F6TKE5_CIOINGuanylate cyclase domain-containing protein. (201 aa)
LOC100181027Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (230 aa)
pdedeltaPhosphodiesterase delta-like protein; Belongs to the PDE6D/unc-119 family. (153 aa)
F6SKP5_CIOINUncharacterized protein; Belongs to the 5'-nucleotidase family. (462 aa)
LOC100178564MGS domain-containing protein. (594 aa)
LOC100186749UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (212 aa)
ci-ak58Radial spoke protein AK58; Belongs to the adenylate kinase family. (485 aa)
F6YNT4_CIOINCoronin; Belongs to the WD repeat coronin family. (925 aa)
LOC100175447PfkB domain-containing protein. (356 aa)
LOC100182043GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (228 aa)
F6TAK8_CIOINUncharacterized protein. (367 aa)
F7BQ75_CIOINPhosphodiesterase. (784 aa)
LOC100181174Uncharacterized protein. (403 aa)
F6YQS6_CIOINAMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (651 aa)
F7BBQ5_CIOINNucleoside diphosphate kinase. (163 aa)
F7A9J1_CIOINPhosphodiesterase. (879 aa)
LOC100185509Cytosolic 5'-nucleotidase 1A. (361 aa)
LOC100176897Uncharacterized protein. (688 aa)
LOC100185251-2Zinc finger protein. (339 aa)
LOC100177271Uncharacterized protein. (454 aa)
LOC100179541HD domain-containing protein 2-like isoform X1. (193 aa)
F6Q548_CIOINUncharacterized protein. (368 aa)
F6QW33_CIOINPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (316 aa)
LOC100182436GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (346 aa)
F6U053_CIOINPDEase_I_N domain-containing protein. (271 aa)
LOC100182227UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (206 aa)
LOC100183100Uncharacterized protein LOC100183100. (202 aa)
F6VKX1_CIOINUridine-cytidine kinase; Belongs to the uridine kinase family. (243 aa)
LOC100183021Cytosolic purine 5'-nucleotidase isoform X4. (548 aa)
F6SJ18_CIOINA to I editase domain-containing protein. (327 aa)
F6Z6J2_CIOINPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
LOC100177202Uncharacterized protein. (1029 aa)
F6YD09_CIOINGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (608 aa)
F6T1L5_CIOINCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (551 aa)
F7BJC2_CIOINGlutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (703 aa)
F6QF37_CIOINAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (440 aa)
LOC100177393Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
F6WWW9_CIOIN5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (288 aa)
F6TK42_CIOINGuanylate cyclase domain-containing protein. (223 aa)
LOC100178005Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
F6XHJ8_CIOINNUC domain-containing protein. (475 aa)
F7B963_CIOINCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
F7APS6_CIOINNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (478 aa)
LOC113474072Thymidylate kinase-like. (209 aa)
LOC100185848Deacetylase sirtuin-type domain-containing protein. (357 aa)
F6USH9_CIOINInosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family. (384 aa)
F6USG9_CIOINIMPDH domain-containing protein. (193 aa)
LOC100186893UMP-CMP kinase 2, mitochondrial-like. (420 aa)
F7ASW5_CIOINPALP domain-containing protein. (187 aa)
F6ZQL1_CIOINHNOB domain-containing protein. (201 aa)
LOC100178048Fatty acid-binding protein 2, liver-like. (131 aa)
F6TT30_CIOINCTP_transf_like domain-containing protein. (242 aa)
ci-ndk/dm44Radial spoke protein NDK/DM44; Belongs to the NDK family. (388 aa)
LOC100180887Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
F6ZC01_CIOINCMP/dCMP-type deaminase domain-containing protein. (191 aa)
LOC100175348U8 snoRNA-decapping enzyme-like isoform X2. (202 aa)
F6YSG2_CIOINRWD domain-containing protein. (260 aa)
F7A5R9_CIOINUncharacterized protein. (342 aa)
LOC778889Deacetylase sirtuin-type domain-containing protein. (319 aa)
F6SLD6_CIOINDeacetylase sirtuin-type domain-containing protein. (737 aa)
F6PJS6_CIOINAB hydrolase-1 domain-containing protein. (414 aa)
LOC100183847dUTPase domain-containing protein. (172 aa)
LOC100187016Mitochondrial import inner membrane translocase subunit tim16-B. (132 aa)
H2XMC4_CIOINUncharacterized protein. (78 aa)
LOC100184518Uridine phosphorylase 2. (311 aa)
H2XPZ0_CIOINCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (155 aa)
H2XQZ0_CIOINUncharacterized protein. (193 aa)
H2XT70_CIOINThymidine kinase. (177 aa)
H2XV35_CIOINCMP/dCMP-type deaminase domain-containing protein. (361 aa)
sir2-aNAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (363 aa)
H2XWF2_CIOINNAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (278 aa)
H2XZK6_CIOINA_deaminase domain-containing protein. (365 aa)
H2Y002_CIOINProtein kinase domain-containing protein. (239 aa)
LOC100186031Adenine phosphoribosyltransferase-like. (185 aa)
H2Y0K0_CIOINNudix hydrolase domain-containing protein. (175 aa)
H2Y0S2_CIOINPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (221 aa)
H2Y207_CIOINA_deaminase domain-containing protein. (263 aa)
H2Y237_CIOINDUF3504 domain-containing protein. (201 aa)
H2Y3J4_CIOINFlavokinase domain-containing protein. (181 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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