(21 nodes) Pyrimidine metabolism network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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Predicted Interactions

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Your Input:
	F6WSV9_CIOIN	A_deaminase domain-containing protein. (361 aa)
	LOC100181977	Uncharacterized protein. (232 aa)
	F6WZU2_CIOIN	dNK domain-containing protein. (265 aa)
	LOC100186604	Uridine-cytidine kinase; Belongs to the uridine kinase family. (505 aa)
	F6SKP5_CIOIN	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (462 aa)
	LOC100186749	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (212 aa)
	LOC100175447	PfkB domain-containing protein. (356 aa)
	F6VKX1_CIOIN	Uridine-cytidine kinase; Belongs to the uridine kinase family. (243 aa)
	LOC100183021	Cytosolic purine 5'-nucleotidase isoform X4. (548 aa)
	F6Z6J2_CIOIN	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
	F6WWW9_CIOIN	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (288 aa)
	LOC100178005	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
	F7B963_CIOIN	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
	LOC113474072	Thymidylate kinase-like. (209 aa)
	LOC100186893	UMP-CMP kinase 2, mitochondrial-like. (420 aa)
	F6ZC01_CIOIN	CMP/dCMP-type deaminase domain-containing protein. (191 aa)
	F6YSG2_CIOIN	RWD domain-containing protein. (260 aa)
	LOC100183847	dUTPase domain-containing protein. (172 aa)
	LOC100184518	Uridine phosphorylase 2. (311 aa)
	H2XPZ0_CIOIN	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (155 aa)
	H2XT70_CIOIN	Thymidine kinase. (177 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6SKP5_CIOIN	F6VKX1_CIOIN	ENSCINP00000008305	ENSCINP00000014825	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.913
F6SKP5_CIOIN	F6WSV9_CIOIN	ENSCINP00000008305	ENSCINP00000004062	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	A_deaminase domain-containing protein.	0.960
F6SKP5_CIOIN	F6WWW9_CIOIN	ENSCINP00000008305	ENSCINP00000019385	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.908
F6SKP5_CIOIN	F6WZU2_CIOIN	ENSCINP00000008305	ENSCINP00000005755	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	dNK domain-containing protein.	0.909
F6SKP5_CIOIN	F6Z6J2_CIOIN	ENSCINP00000008305	ENSCINP00000016539	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.979
F6SKP5_CIOIN	F7B963_CIOIN	ENSCINP00000008305	ENSCINP00000022100	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.917
F6SKP5_CIOIN	H2XPZ0_CIOIN	ENSCINP00000008305	ENSCINP00000031724	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.917
F6SKP5_CIOIN	H2XT70_CIOIN	ENSCINP00000008305	ENSCINP00000032854	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Thymidine kinase.	0.912
F6SKP5_CIOIN	LOC100175447	ENSCINP00000008305	ENSCINP00000009198	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	PfkB domain-containing protein.	0.949
F6SKP5_CIOIN	LOC100178005	ENSCINP00000008305	ENSCINP00000020265	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.917
F6SKP5_CIOIN	LOC100181977	ENSCINP00000008305	ENSCINP00000005217	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.913
F6SKP5_CIOIN	LOC100183021	ENSCINP00000008305	ENSCINP00000015119	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Cytosolic purine 5'-nucleotidase isoform X4.	0.911
F6SKP5_CIOIN	LOC100183847	ENSCINP00000008305	ENSCINP00000029413	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	dUTPase domain-containing protein.	0.902
F6SKP5_CIOIN	LOC100184518	ENSCINP00000008305	ENSCINP00000031490	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uridine phosphorylase 2.	0.975
F6SKP5_CIOIN	LOC100186604	ENSCINP00000008305	ENSCINP00000007462	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.914
F6SKP5_CIOIN	LOC100186749	ENSCINP00000008305	ENSCINP00000008568	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.908
F6SKP5_CIOIN	LOC100186893	ENSCINP00000008305	ENSCINP00000023560	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	UMP-CMP kinase 2, mitochondrial-like.	0.916
F6SKP5_CIOIN	LOC113474072	ENSCINP00000008305	ENSCINP00000022607	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Thymidylate kinase-like.	0.916
F6VKX1_CIOIN	F6SKP5_CIOIN	ENSCINP00000014825	ENSCINP00000008305	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.913
F6VKX1_CIOIN	F6WWW9_CIOIN	ENSCINP00000014825	ENSCINP00000019385	Uridine-cytidine kinase; Belongs to the uridine kinase family.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.904