(20 nodes) Sphingolipid metabolism network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100178882	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (167 aa)
	F6PH94_CIOIN	Uncharacterized protein. (268 aa)
	F6TI55_CIOIN	Uncharacterized protein. (753 aa)
	LOC100184115	Ceramide synthase 1. (335 aa)
	F6Q8G4_CIOIN	Uncharacterized protein; Belongs to the acid ceramidase family. (392 aa)
	F6ZYB8_CIOIN	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (599 aa)
	LOC100186563	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (599 aa)
	lag1-like1	Transcription factor protein. (382 aa)
	F7AA01_CIOIN	Glucosylceramidase. (561 aa)
	F7A1T4_CIOIN	Uncharacterized protein. (401 aa)
	F6Y921_CIOIN	Glyco_hydro_59M domain-containing protein. (677 aa)
	LOC100178733	Sphingolipid delta(4)-desaturase DES1-like; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. (322 aa)
	F6TJR3_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (242 aa)
	F6VAL7_CIOIN	Uncharacterized protein. (235 aa)
	F7AN60_CIOIN	Uncharacterized protein. (424 aa)
	F7AV79_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (228 aa)
	H2XJY8_CIOIN	Glucosylceramidase. (518 aa)
	H2XM50_CIOIN	Lipid_DES domain-containing protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. (323 aa)
	H2XMX0_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (143 aa)
	LOC100177090	Ceramide synthase 1-like. (344 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PH94_CIOIN	F6Q8G4_CIOIN	ENSCINP00000001408	ENSCINP00000004990	Uncharacterized protein.	Uncharacterized protein; Belongs to the acid ceramidase family.	0.664
F6PH94_CIOIN	F6TI55_CIOIN	ENSCINP00000001408	ENSCINP00000002919	Uncharacterized protein.	Uncharacterized protein.	0.908
F6PH94_CIOIN	F6TJR3_CIOIN	ENSCINP00000001408	ENSCINP00000021779	Uncharacterized protein.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.652
F6PH94_CIOIN	F6VAL7_CIOIN	ENSCINP00000001408	ENSCINP00000022564	Uncharacterized protein.	Uncharacterized protein.	0.903
F6PH94_CIOIN	F6Y921_CIOIN	ENSCINP00000001408	ENSCINP00000019330	Uncharacterized protein.	Glyco_hydro_59M domain-containing protein.	0.900
F6PH94_CIOIN	F6ZYB8_CIOIN	ENSCINP00000001408	ENSCINP00000005699	Uncharacterized protein.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family.	0.906
F6PH94_CIOIN	F7A1T4_CIOIN	ENSCINP00000001408	ENSCINP00000017071	Uncharacterized protein.	Uncharacterized protein.	0.901
F6PH94_CIOIN	F7AA01_CIOIN	ENSCINP00000001408	ENSCINP00000016220	Uncharacterized protein.	Glucosylceramidase.	0.900
F6PH94_CIOIN	F7AN60_CIOIN	ENSCINP00000001408	ENSCINP00000022682	Uncharacterized protein.	Uncharacterized protein.	0.902
F6PH94_CIOIN	F7AV79_CIOIN	ENSCINP00000001408	ENSCINP00000023348	Uncharacterized protein.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.652
F6PH94_CIOIN	H2XJY8_CIOIN	ENSCINP00000001408	ENSCINP00000029970	Uncharacterized protein.	Glucosylceramidase.	0.900
F6PH94_CIOIN	H2XM50_CIOIN	ENSCINP00000001408	ENSCINP00000030732	Uncharacterized protein.	Lipid_DES domain-containing protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.	0.902
F6PH94_CIOIN	H2XMX0_CIOIN	ENSCINP00000001408	ENSCINP00000031003	Uncharacterized protein.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.650
F6PH94_CIOIN	LOC100177090	ENSCINP00000001408	ENSCINP00000031017	Uncharacterized protein.	Ceramide synthase 1-like.	0.900
F6PH94_CIOIN	LOC100178733	ENSCINP00000001408	ENSCINP00000020056	Uncharacterized protein.	Sphingolipid delta(4)-desaturase DES1-like; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.	0.902
F6PH94_CIOIN	LOC100178882	ENSCINP00000001408	ENSCINP00000000095	Uncharacterized protein.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.652
F6PH94_CIOIN	LOC100184115	ENSCINP00000001408	ENSCINP00000002922	Uncharacterized protein.	Ceramide synthase 1.	0.900
F6PH94_CIOIN	LOC100186563	ENSCINP00000001408	ENSCINP00000006326	Uncharacterized protein.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family.	0.906
F6PH94_CIOIN	lag1-like1	ENSCINP00000001408	ENSCINP00000012517	Uncharacterized protein.	Transcription factor protein.	0.900
F6Q8G4_CIOIN	F6PH94_CIOIN	ENSCINP00000004990	ENSCINP00000001408	Uncharacterized protein; Belongs to the acid ceramidase family.	Uncharacterized protein.	0.664