(22 nodes) GPI anchor metabolic process network (Ciona intestinalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	F6YLE1_CIOIN	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (919 aa)
	F6YG81_CIOIN	CASP_C domain-containing protein. (655 aa)
	F6ZQH5_CIOIN	Uncharacterized protein. (250 aa)
	LOC100175389	Uncharacterized protein. (350 aa)
	F6S8C9_CIOIN	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (122 aa)
	F7A2R6_CIOIN	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (501 aa)
	LOC100178746	Uncharacterized protein. (429 aa)
	F6QM57_CIOIN	Prenylcys_lyase domain-containing protein. (466 aa)
	F6X8F0_CIOIN	RGS domain-containing protein. (394 aa)
	F6X6G2_CIOIN	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (221 aa)
	F6RR57_CIOIN	Mannosyltransferase. (442 aa)
	LOC100180163	post-GPI attachment to proteins factor 2-like. (256 aa)
	F6ZRT4_CIOIN	Uncharacterized protein. (1001 aa)
	LOC100179414	Phosphatidylinositol glycan anchor biosynthesis class U protein. (431 aa)
	F6WBQ8_CIOIN	Metallophos domain-containing protein. (211 aa)
	H2XMD0_CIOIN	Uncharacterized protein. (128 aa)
	H2XMX2_CIOIN	Uncharacterized protein. (513 aa)
	H2XMY8_CIOIN	Uncharacterized protein. (55 aa)
	H2XNH3_CIOIN	Uncharacterized protein. (277 aa)
	H2XP51_CIOIN	Uncharacterized protein. (980 aa)
	H2XVJ7_CIOIN	Uncharacterized protein. (507 aa)
	LOC100177059	PigN domain-containing protein. (919 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QM57_CIOIN	LOC100180163	ENSCINP00000020126	ENSCINP00000026473	Prenylcys_lyase domain-containing protein.	post-GPI attachment to proteins factor 2-like.	0.497
F6RR57_CIOIN	F6S8C9_CIOIN	ENSCINP00000025105	ENSCINP00000014961	Mannosyltransferase.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.642
F6RR57_CIOIN	F6X6G2_CIOIN	ENSCINP00000025105	ENSCINP00000022793	Mannosyltransferase.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.646
F6RR57_CIOIN	F6X8F0_CIOIN	ENSCINP00000025105	ENSCINP00000022227	Mannosyltransferase.	RGS domain-containing protein.	0.645
F6RR57_CIOIN	F6ZQH5_CIOIN	ENSCINP00000025105	ENSCINP00000009396	Mannosyltransferase.	Uncharacterized protein.	0.475
F6RR57_CIOIN	F6ZRT4_CIOIN	ENSCINP00000025105	ENSCINP00000028216	Mannosyltransferase.	Uncharacterized protein.	0.642
F6RR57_CIOIN	F7A2R6_CIOIN	ENSCINP00000025105	ENSCINP00000015815	Mannosyltransferase.	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	0.493
F6RR57_CIOIN	H2XMX2_CIOIN	ENSCINP00000025105	ENSCINP00000031005	Mannosyltransferase.	Uncharacterized protein.	0.484
F6RR57_CIOIN	H2XP51_CIOIN	ENSCINP00000025105	ENSCINP00000031434	Mannosyltransferase.	Uncharacterized protein.	0.535
F6RR57_CIOIN	LOC100175389	ENSCINP00000025105	ENSCINP00000013500	Mannosyltransferase.	Uncharacterized protein.	0.510
F6RR57_CIOIN	LOC100177059	ENSCINP00000025105	ENSCINP00000035708	Mannosyltransferase.	PigN domain-containing protein.	0.589
F6S8C9_CIOIN	F6RR57_CIOIN	ENSCINP00000014961	ENSCINP00000025105	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Mannosyltransferase.	0.642
F6S8C9_CIOIN	F6X6G2_CIOIN	ENSCINP00000014961	ENSCINP00000022793	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.644
F6S8C9_CIOIN	F6X8F0_CIOIN	ENSCINP00000014961	ENSCINP00000022227	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	RGS domain-containing protein.	0.642
F6S8C9_CIOIN	F6YLE1_CIOIN	ENSCINP00000014961	ENSCINP00000001839	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	0.648
F6S8C9_CIOIN	F6ZQH5_CIOIN	ENSCINP00000014961	ENSCINP00000009396	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.642
F6S8C9_CIOIN	F6ZRT4_CIOIN	ENSCINP00000014961	ENSCINP00000028216	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.663
F6S8C9_CIOIN	F7A2R6_CIOIN	ENSCINP00000014961	ENSCINP00000015815	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	0.474
F6S8C9_CIOIN	H2XMX2_CIOIN	ENSCINP00000014961	ENSCINP00000031005	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.999
F6S8C9_CIOIN	H2XMY8_CIOIN	ENSCINP00000014961	ENSCINP00000031021	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.506