(82 nodes) Mixed, incl. Inositol phosphate metabolism, and Phosphatidylinositol phosphate biosynthetic process network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6SF88_CIOIN	Phosphoinositide phospholipase C. (826 aa)
	LOC100182904	Uncharacterized protein. (295 aa)
	F6ZD22_CIOIN	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (265 aa)
	LOC100180551	Inositol-1-monophosphatase. (275 aa)
	LOC100183445	3-hydroxybutyrate dehydrogenase type 2-like. (248 aa)
	F7AAA7_CIOIN	PI3K/PI4K domain-containing protein. (509 aa)
	LOC100182434	Uncharacterized protein. (403 aa)
	F6QH36_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1667 aa)
	LOC100180419	Golgi phosphoprotein 3-like. (291 aa)
	LOC100180066	Sodium/hydrogen exchanger 9B2-like. (535 aa)
	LOC100182374	Kinase; Belongs to the inositol phosphokinase (IPK) family. (431 aa)
	F6WMZ2_CIOIN	PIPK domain-containing protein. (453 aa)
	F6XJF3_CIOIN	Anoctamin. (676 aa)
	LOC100181790	Uncharacterized protein. (169 aa)
	F7AY24_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (653 aa)
	LOC100181041	Myotubularin-related protein 9 isoform X1. (562 aa)
	LOC100185699	Inositol oxygenase-like isoform X1. (285 aa)
	LOC100185660	Phosphoinositide phospholipase C. (758 aa)
	F7AVL3_CIOIN	CRAL-TRIO domain-containing protein. (269 aa)
	F6YQG3_CIOIN	Uncharacterized protein. (106 aa)
	LOC100183109	Neuronal calcium sensor 1-like. (190 aa)
	LOC100185166	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (214 aa)
	LOC100180880	Uncharacterized protein. (356 aa)
	F6PQJ9_CIOIN	PIPK domain-containing protein. (165 aa)
	LOC100180112	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1106 aa)
	F6SUV6_CIOIN	Myotubularin phosphatase domain-containing protein. (223 aa)
	LOC100182371	Uncharacterized protein. (609 aa)
	F6RYU3_CIOIN	Uncharacterized protein. (352 aa)
	LOC100178482	Uncharacterized protein. (180 aa)
	LOC100178371	Stabilizer of axonemal microtubules 2. (429 aa)
	F6Z7W1_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (697 aa)
	F6S5E1_CIOIN	Uncharacterized protein. (221 aa)
	LOC100182691	SAC domain-containing protein. (590 aa)
	LOC100181424	Uncharacterized protein. (719 aa)
	F7BIS1_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (847 aa)
	F6Q8X5_CIOIN	Uncharacterized protein. (449 aa)
	F6WXB6_CIOIN	Na_H_Exchanger domain-containing protein. (462 aa)
	F6ZUQ2_CIOIN	Kinase; Belongs to the inositol phosphokinase (IPK) family. (412 aa)
	LOC100181593	Vesicle-associated membrane protein-associated protein B-like. (233 aa)
	F6WPL1_CIOIN	Uncharacterized protein. (80 aa)
	F6PT06_CIOIN	Uncharacterized protein. (183 aa)
	F6VTM3_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (673 aa)
	F7BLX1_CIOIN	Uncharacterized protein. (253 aa)
	F6RJ12_CIOIN	Kinase; Belongs to the inositol phosphokinase (IPK) family. (295 aa)
	F6TE65_CIOIN	Na_H_Exchanger domain-containing protein. (254 aa)
	F6WA81_CIOIN	Phospholipase. (1145 aa)
	F6SAN3_CIOIN	Phosphoinositide phospholipase C. (486 aa)
	LOC100178124	Inositol monophosphatase 3-like. (324 aa)
	F6UW73_CIOIN	Uncharacterized protein. (301 aa)
	LOC100183841	Uncharacterized protein. (249 aa)
	F6ZIX0_CIOIN	Kinase; Belongs to the inositol phosphokinase (IPK) family. (143 aa)
	LOC100177728	Solute carrier family 22 member 18. (399 aa)
	LOC100180708	Tetratricopeptide repeat protein 7B-like. (810 aa)
	H2XMJ7_CIOIN	IPPc domain-containing protein. (430 aa)
	H2XMW5_CIOIN	Uncharacterized protein. (251 aa)
	H2XPG3_CIOIN	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1081 aa)
	H2XQD2_CIOIN	CRAL-TRIO domain-containing protein. (242 aa)
	H2XQI8_CIOIN	DUF1866 domain-containing protein. (194 aa)
	H2XRY3_CIOIN	Uncharacterized protein. (183 aa)
	LOC101243120	B-cell receptor-associated protein 31. (229 aa)
	H2XTX3_CIOIN	Uncharacterized protein. (297 aa)
	H2XU61_CIOIN	Uncharacterized protein. (469 aa)
	H2XUG2_CIOIN	Uncharacterized protein. (148 aa)
	H2XUH0_CIOIN	Ins134_P3_kin domain-containing protein. (157 aa)
	LOC100179084	CRAL-TRIO domain-containing protein. (230 aa)
	H2XW92_CIOIN	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (229 aa)
	H2XWF6_CIOIN	Kinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
	H2XWG3_CIOIN	Uncharacterized protein. (117 aa)
	H2XWM6_CIOIN	DUF1741 domain-containing protein. (686 aa)
	H2XWT1_CIOIN	Uncharacterized protein. (235 aa)
	H2XYE3_CIOIN	SMP-LTD domain-containing protein. (298 aa)
	H2XZI8_CIOIN	CRAL-TRIO domain-containing protein. (235 aa)
	LOC100180280	MSP domain-containing protein. (258 aa)
	H2Y0G7_CIOIN	PH domain-containing protein. (160 aa)
	H2Y1I5_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1216 aa)
	H2Y2C6_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (734 aa)
	LOC100185018	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (411 aa)
	H2Y2Z5_CIOIN	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (194 aa)
	H2Y342_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (228 aa)
	H2Y3H4_CIOIN	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (204 aa)
	H2Y3P6_CIOIN	Rho-GAP domain-containing protein. (708 aa)
	H2Y3S2_CIOIN	Uncharacterized protein. (138 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PQJ9_CIOIN	F6PT06_CIOIN	ENSCINP00000013393	ENSCINP00000023892	PIPK domain-containing protein.	Uncharacterized protein.	0.907
F6PQJ9_CIOIN	F6QH36_CIOIN	ENSCINP00000013393	ENSCINP00000004941	PIPK domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.504
F6PQJ9_CIOIN	F6S5E1_CIOIN	ENSCINP00000013393	ENSCINP00000016441	PIPK domain-containing protein.	Uncharacterized protein.	0.911
F6PQJ9_CIOIN	F6SAN3_CIOIN	ENSCINP00000013393	ENSCINP00000026357	PIPK domain-containing protein.	Phosphoinositide phospholipase C.	0.927
F6PQJ9_CIOIN	F6SF88_CIOIN	ENSCINP00000013393	ENSCINP00000000483	PIPK domain-containing protein.	Phosphoinositide phospholipase C.	0.911
F6PQJ9_CIOIN	F6SUV6_CIOIN	ENSCINP00000013393	ENSCINP00000014950	PIPK domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.900
F6PQJ9_CIOIN	F6WMZ2_CIOIN	ENSCINP00000013393	ENSCINP00000006755	PIPK domain-containing protein.	PIPK domain-containing protein.	0.900
F6PQJ9_CIOIN	F6ZD22_CIOIN	ENSCINP00000013393	ENSCINP00000002133	PIPK domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.911
F6PQJ9_CIOIN	F7BIS1_CIOIN	ENSCINP00000013393	ENSCINP00000017962	PIPK domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.660
F6PQJ9_CIOIN	F7BLX1_CIOIN	ENSCINP00000013393	ENSCINP00000024453	PIPK domain-containing protein.	Uncharacterized protein.	0.909
F6PQJ9_CIOIN	H2XQI8_CIOIN	ENSCINP00000013393	ENSCINP00000031922	PIPK domain-containing protein.	DUF1866 domain-containing protein.	0.917
F6PQJ9_CIOIN	H2XRY3_CIOIN	ENSCINP00000013393	ENSCINP00000032417	PIPK domain-containing protein.	Uncharacterized protein.	0.911
F6PQJ9_CIOIN	H2Y3P6_CIOIN	ENSCINP00000013393	ENSCINP00000036531	PIPK domain-containing protein.	Rho-GAP domain-containing protein.	0.908
F6PQJ9_CIOIN	LOC100180112	ENSCINP00000013393	ENSCINP00000014240	PIPK domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.920
F6PQJ9_CIOIN	LOC100182371	ENSCINP00000013393	ENSCINP00000015031	PIPK domain-containing protein.	Uncharacterized protein.	0.915
F6PQJ9_CIOIN	LOC100182434	ENSCINP00000013393	ENSCINP00000004848	PIPK domain-containing protein.	Uncharacterized protein.	0.910
F6PQJ9_CIOIN	LOC100185660	ENSCINP00000013393	ENSCINP00000009407	PIPK domain-containing protein.	Phosphoinositide phospholipase C.	0.927
F6PT06_CIOIN	F6PQJ9_CIOIN	ENSCINP00000023892	ENSCINP00000013393	Uncharacterized protein.	PIPK domain-containing protein.	0.907
F6PT06_CIOIN	F6S5E1_CIOIN	ENSCINP00000023892	ENSCINP00000016441	Uncharacterized protein.	Uncharacterized protein.	0.901
F6PT06_CIOIN	F6SAN3_CIOIN	ENSCINP00000023892	ENSCINP00000026357	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.902