(26 nodes) Mixed, incl. Small GTPase Rho, and Formin, FH2 domain network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdc42	Uncharacterized protein. (95 aa)
	LOC448957	Rac4 protein. (193 aa)
	LOC445702	Rac1 protein isoform X1. (192 aa)
	ci-arfgap-3	Zinc finger protein Ci-ArfGAP-3. (760 aa)
	F7BJE1_CIOIN	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (213 aa)
	rhoc	RhoA protein. (193 aa)
	F6R6F3_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1324 aa)
	F6WYA7_CIOIN	SH3 domain-containing protein. (166 aa)
	F7AXL0_CIOIN	Uncharacterized protein. (1039 aa)
	F6U465_CIOIN	Uncharacterized protein. (743 aa)
	F6ZCE0_CIOIN	Non-specific serine/threonine protein kinase. (619 aa)
	LOC445704	TC10 protein. (193 aa)
	Rac2	Uncharacterized protein. (192 aa)
	F7BLG0_CIOIN	Uncharacterized protein. (527 aa)
	F6V341_CIOIN	Uncharacterized protein. (331 aa)
	F6YAG6_CIOIN	Uncharacterized protein. (403 aa)
	H2XMB5_CIOIN	Uncharacterized protein. (116 aa)
	H2XPI6_CIOIN	DH domain-containing protein. (166 aa)
	H2XQ68_CIOIN	Drf_GBD domain-containing protein. (190 aa)
	H2XVF8_CIOIN	Non-specific serine/threonine protein kinase. (699 aa)
	H2XVP3_CIOIN	FH2 domain-containing protein. (145 aa)
	H2XVQ2_CIOIN	Uncharacterized protein. (1694 aa)
	H2XZX4_CIOIN	FH2 domain-containing protein. (220 aa)
	H2XZX6_CIOIN	Phorbol-ester/DAG-type domain-containing protein. (399 aa)
	Rhou	Uncharacterized protein. (259 aa)
	H2Y3I9_CIOIN	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (222 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R6F3_CIOIN	F6V341_CIOIN	ENSCINP00000006395	ENSCINP00000024665	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.415
F6R6F3_CIOIN	F6ZCE0_CIOIN	ENSCINP00000006395	ENSCINP00000014470	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Non-specific serine/threonine protein kinase.	0.413
F6R6F3_CIOIN	LOC445704	ENSCINP00000006395	ENSCINP00000018289	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	TC10 protein.	0.548
F6R6F3_CIOIN	cdc42	ENSCINP00000006395	ENSCINP00000001500	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.470
F6R6F3_CIOIN	rhoc	ENSCINP00000006395	ENSCINP00000006386	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	RhoA protein.	0.992
F6U465_CIOIN	F6WYA7_CIOIN	ENSCINP00000011565	ENSCINP00000007053	Uncharacterized protein.	SH3 domain-containing protein.	0.435
F6U465_CIOIN	F6YAG6_CIOIN	ENSCINP00000011565	ENSCINP00000026156	Uncharacterized protein.	Uncharacterized protein.	0.435
F6U465_CIOIN	F6ZCE0_CIOIN	ENSCINP00000011565	ENSCINP00000014470	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.407
F6U465_CIOIN	H2XMB5_CIOIN	ENSCINP00000011565	ENSCINP00000030798	Uncharacterized protein.	Uncharacterized protein.	0.465
F6U465_CIOIN	H2XVF8_CIOIN	ENSCINP00000011565	ENSCINP00000033642	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.407
F6U465_CIOIN	H2XZX6_CIOIN	ENSCINP00000011565	ENSCINP00000035210	Uncharacterized protein.	Phorbol-ester/DAG-type domain-containing protein.	0.909
F6U465_CIOIN	H2Y3I9_CIOIN	ENSCINP00000011565	ENSCINP00000036474	Uncharacterized protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.909
F6U465_CIOIN	LOC445702	ENSCINP00000011565	ENSCINP00000004782	Uncharacterized protein.	Rac1 protein isoform X1.	0.465
F6U465_CIOIN	LOC445704	ENSCINP00000011565	ENSCINP00000018289	Uncharacterized protein.	TC10 protein.	0.465
F6U465_CIOIN	LOC448957	ENSCINP00000011565	ENSCINP00000004748	Uncharacterized protein.	Rac4 protein.	0.465
F6U465_CIOIN	Rac2	ENSCINP00000011565	ENSCINP00000024029	Uncharacterized protein.	Uncharacterized protein.	0.465
F6U465_CIOIN	Rhou	ENSCINP00000011565	ENSCINP00000035599	Uncharacterized protein.	Uncharacterized protein.	0.465
F6U465_CIOIN	cdc42	ENSCINP00000011565	ENSCINP00000001500	Uncharacterized protein.	Uncharacterized protein.	0.518
F6U465_CIOIN	rhoc	ENSCINP00000011565	ENSCINP00000006386	Uncharacterized protein.	RhoA protein.	0.611
F6V341_CIOIN	F6R6F3_CIOIN	ENSCINP00000024665	ENSCINP00000006395	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.415