(14 nodes) Mixed, incl. Small GTPase Rho, and p21 activated kinase binding domain network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdc42	Uncharacterized protein. (95 aa)
	LOC448957	Rac4 protein. (193 aa)
	ci-arfgap-3	Zinc finger protein Ci-ArfGAP-3. (760 aa)
	rhoc	RhoA protein. (193 aa)
	F6R6F3_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1324 aa)
	F6ZCE0_CIOIN	Non-specific serine/threonine protein kinase. (619 aa)
	LOC445704	TC10 protein. (193 aa)
	Rac2	Uncharacterized protein. (192 aa)
	F7BLG0_CIOIN	Uncharacterized protein. (527 aa)
	F6V341_CIOIN	Uncharacterized protein. (331 aa)
	H2XMB5_CIOIN	Uncharacterized protein. (116 aa)
	H2XPI6_CIOIN	DH domain-containing protein. (166 aa)
	H2XVF8_CIOIN	Non-specific serine/threonine protein kinase. (699 aa)
	H2XVQ2_CIOIN	Uncharacterized protein. (1694 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R6F3_CIOIN	F6V341_CIOIN	ENSCINP00000006395	ENSCINP00000024665	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.415
F6R6F3_CIOIN	F6ZCE0_CIOIN	ENSCINP00000006395	ENSCINP00000014470	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Non-specific serine/threonine protein kinase.	0.413
F6R6F3_CIOIN	LOC445704	ENSCINP00000006395	ENSCINP00000018289	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	TC10 protein.	0.548
F6R6F3_CIOIN	cdc42	ENSCINP00000006395	ENSCINP00000001500	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.470
F6R6F3_CIOIN	rhoc	ENSCINP00000006395	ENSCINP00000006386	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	RhoA protein.	0.992
F6V341_CIOIN	F6R6F3_CIOIN	ENSCINP00000024665	ENSCINP00000006395	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.415
F6V341_CIOIN	F7BLG0_CIOIN	ENSCINP00000024665	ENSCINP00000024474	Uncharacterized protein.	Uncharacterized protein.	0.518
F6V341_CIOIN	H2XMB5_CIOIN	ENSCINP00000024665	ENSCINP00000030798	Uncharacterized protein.	Uncharacterized protein.	0.454
F6V341_CIOIN	H2XVQ2_CIOIN	ENSCINP00000024665	ENSCINP00000033736	Uncharacterized protein.	Uncharacterized protein.	0.637
F6V341_CIOIN	LOC445704	ENSCINP00000024665	ENSCINP00000018289	Uncharacterized protein.	TC10 protein.	0.454
F6V341_CIOIN	LOC448957	ENSCINP00000024665	ENSCINP00000004748	Uncharacterized protein.	Rac4 protein.	0.463
F6V341_CIOIN	Rac2	ENSCINP00000024665	ENSCINP00000024029	Uncharacterized protein.	Uncharacterized protein.	0.463
F6V341_CIOIN	cdc42	ENSCINP00000024665	ENSCINP00000001500	Uncharacterized protein.	Uncharacterized protein.	0.536
F6V341_CIOIN	rhoc	ENSCINP00000024665	ENSCINP00000006386	Uncharacterized protein.	RhoA protein.	0.959
F6ZCE0_CIOIN	F6R6F3_CIOIN	ENSCINP00000014470	ENSCINP00000006395	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.413
F6ZCE0_CIOIN	F7BLG0_CIOIN	ENSCINP00000014470	ENSCINP00000024474	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.978
F6ZCE0_CIOIN	H2XMB5_CIOIN	ENSCINP00000014470	ENSCINP00000030798	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.533
F6ZCE0_CIOIN	H2XVF8_CIOIN	ENSCINP00000014470	ENSCINP00000033642	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.533
F6ZCE0_CIOIN	H2XVQ2_CIOIN	ENSCINP00000014470	ENSCINP00000033736	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.905
F6ZCE0_CIOIN	LOC445704	ENSCINP00000014470	ENSCINP00000018289	Non-specific serine/threonine protein kinase.	TC10 protein.	0.636