(5 nodes) Wnt signaling pathway, planar cell polarity pathway, and PET Domain network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6U8A8_CIOIN	Vang-like protein. (507 aa)
	F6URP5_CIOIN	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (2554 aa)
	Pk1	Uncharacterized protein. (1060 aa)
	dsh	Dishevelled homolog. (685 aa)
	H2XMN9_CIOIN	Drf_GBD domain-containing protein. (189 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6U8A8_CIOIN	F6URP5_CIOIN	ENSCINP00000007464	ENSCINP00000011544	Vang-like protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.708
F6U8A8_CIOIN	H2XMN9_CIOIN	ENSCINP00000007464	ENSCINP00000030922	Vang-like protein.	Drf_GBD domain-containing protein.	0.452
F6U8A8_CIOIN	Pk1	ENSCINP00000007464	ENSCINP00000013790	Vang-like protein.	Uncharacterized protein.	0.866
F6U8A8_CIOIN	dsh	ENSCINP00000007464	ENSCINP00000019640	Vang-like protein.	Dishevelled homolog.	0.925
F6URP5_CIOIN	F6U8A8_CIOIN	ENSCINP00000011544	ENSCINP00000007464	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Vang-like protein.	0.708
F6URP5_CIOIN	Pk1	ENSCINP00000011544	ENSCINP00000013790	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.692
F6URP5_CIOIN	dsh	ENSCINP00000011544	ENSCINP00000019640	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Dishevelled homolog.	0.639
H2XMN9_CIOIN	F6U8A8_CIOIN	ENSCINP00000030922	ENSCINP00000007464	Drf_GBD domain-containing protein.	Vang-like protein.	0.452
H2XMN9_CIOIN	dsh	ENSCINP00000030922	ENSCINP00000019640	Drf_GBD domain-containing protein.	Dishevelled homolog.	0.950
Pk1	F6U8A8_CIOIN	ENSCINP00000013790	ENSCINP00000007464	Uncharacterized protein.	Vang-like protein.	0.866
Pk1	F6URP5_CIOIN	ENSCINP00000013790	ENSCINP00000011544	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.692
Pk1	dsh	ENSCINP00000013790	ENSCINP00000019640	Uncharacterized protein.	Dishevelled homolog.	0.994
dsh	F6U8A8_CIOIN	ENSCINP00000019640	ENSCINP00000007464	Dishevelled homolog.	Vang-like protein.	0.925
dsh	F6URP5_CIOIN	ENSCINP00000019640	ENSCINP00000011544	Dishevelled homolog.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.639
dsh	H2XMN9_CIOIN	ENSCINP00000019640	ENSCINP00000030922	Dishevelled homolog.	Drf_GBD domain-containing protein.	0.950
dsh	Pk1	ENSCINP00000019640	ENSCINP00000013790	Dishevelled homolog.	Uncharacterized protein.	0.994