(50 nodes) Tissue homeostasis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XWL5_CIOIN	Metallophos domain-containing protein. (176 aa)
	H2XVI1_CIOIN	Uncharacterized protein. (102 aa)
	H2XTN1_CIOIN	Uncharacterized protein. (141 aa)
	H2XSR0_CIOIN	BTB domain-containing protein. (601 aa)
	srf	Transcription factor protein. (335 aa)
	H2XRJ0_CIOIN	Uncharacterized protein. (90 aa)
	H2XQW5_CIOIN	Uncharacterized protein. (186 aa)
	H2XQ82_CIOIN	Uncharacterized protein. (217 aa)
	H2XPQ9_CIOIN	Uncharacterized protein. (223 aa)
	H2XPG0_CIOIN	Uncharacterized protein. (239 aa)
	H2Y1K9_CIOIN	Uncharacterized protein. (674 aa)
	H2XP59_CIOIN	Uncharacterized protein. (377 aa)
	H2XMJ6_CIOIN	Uncharacterized protein. (204 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	LOC100175015	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (192 aa)
	nox4	FAD-binding FR-type domain-containing protein. (811 aa)
	F6U0X3_CIOIN	Uncharacterized protein. (154 aa)
	F6RDQ7_CIOIN	Uncharacterized protein. (591 aa)
	LOC100184123	Bardet-Biedl syndrome 2 protein homolog. (708 aa)
	F6PQC6_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
	F6QGN1_CIOIN	WH1 domain-containing protein. (284 aa)
	F6Q2W2_CIOIN	ANK_REP_REGION domain-containing protein. (223 aa)
	F6YVN3_CIOIN	Uncharacterized protein. (165 aa)
	F6U1V3_CIOIN	Uncharacterized protein. (1398 aa)
	Zf(c2h2)-141	Uncharacterized protein. (578 aa)
	F6UHN5_CIOIN	ZU5 domain-containing protein. (51 aa)
	F6WBK6_CIOIN	TPR_REGION domain-containing protein. (446 aa)
	F6WXG6_CIOIN	Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
	F6QX49_CIOIN	Tartrate-resistant acid phosphatase type 5. (330 aa)
	F6YND7_CIOIN	PDZ domain-containing protein. (226 aa)
	F6Z761_CIOIN	Uncharacterized protein. (470 aa)
	F6XU54_CIOIN	Metallophos domain-containing protein. (252 aa)
	F6UJL9_CIOIN	Tartrate-resistant acid phosphatase type 5. (345 aa)
	LOC100184818	Uncharacterized protein. (583 aa)
	LOC100175958	Uncharacterized protein. (815 aa)
	F6RS66_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
	F6ZZ65_CIOIN	Uncharacterized protein. (582 aa)
	LOC100181891	Uncharacterized protein. (373 aa)
	LOC100176263	Lebercilin isoform X4. (727 aa)
	F6RF18_CIOIN	Uncharacterized protein. (5108 aa)
	LOC100180223	Phenazine biosynthesis-like domain-containing protein 1. (289 aa)
	Smoothened	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
	F6ZTV7_CIOIN	CCDC66 domain-containing protein. (714 aa)
	LOC100178560	Pulmonary surfactant-associated protein D-like. (239 aa)
	LOC100176230	WD_REPEATS_REGION domain-containing protein. (328 aa)
	LOC100179981	Uncharacterized protein. (229 aa)
	H2Y1J9_CIOIN	BTB domain-containing protein. (553 aa)
	H2Y074_CIOIN	Uncharacterized protein. (275 aa)
	LOC101243096	Trefoil factor 2-like. (119 aa)
	H2XXZ3_CIOIN	Uncharacterized protein. (870 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6RDQ7_CIOIN	F6U1V3_CIOIN	ENSCINP00000025479	ENSCINP00000023812	Uncharacterized protein.	Uncharacterized protein.	0.590
F6RDQ7_CIOIN	F6ZZ65_CIOIN	ENSCINP00000025479	ENSCINP00000012520	Uncharacterized protein.	Uncharacterized protein.	0.517
F6RDQ7_CIOIN	H2XPG0_CIOIN	ENSCINP00000025479	ENSCINP00000031543	Uncharacterized protein.	Uncharacterized protein.	0.504
F6RDQ7_CIOIN	LOC100184123	ENSCINP00000025479	ENSCINP00000025380	Uncharacterized protein.	Bardet-Biedl syndrome 2 protein homolog.	0.487
F6RF18_CIOIN	F6U0X3_CIOIN	ENSCINP00000009921	ENSCINP00000025602	Uncharacterized protein.	Uncharacterized protein.	0.501
F6RF18_CIOIN	H2XPQ9_CIOIN	ENSCINP00000009921	ENSCINP00000031643	Uncharacterized protein.	Uncharacterized protein.	0.501
F6RF18_CIOIN	LOC100176263	ENSCINP00000009921	ENSCINP00000010552	Uncharacterized protein.	Lebercilin isoform X4.	0.503
F6U0X3_CIOIN	F6RF18_CIOIN	ENSCINP00000025602	ENSCINP00000009921	Uncharacterized protein.	Uncharacterized protein.	0.501
F6U1V3_CIOIN	F6RDQ7_CIOIN	ENSCINP00000023812	ENSCINP00000025479	Uncharacterized protein.	Uncharacterized protein.	0.590
F6U1V3_CIOIN	F6ZZ65_CIOIN	ENSCINP00000023812	ENSCINP00000012520	Uncharacterized protein.	Uncharacterized protein.	0.494
F6U1V3_CIOIN	LOC100184818	ENSCINP00000023812	ENSCINP00000014179	Uncharacterized protein.	Uncharacterized protein.	0.558
F6UJL9_CIOIN	F6XU54_CIOIN	ENSCINP00000015403	ENSCINP00000015905	Tartrate-resistant acid phosphatase type 5.	Metallophos domain-containing protein.	0.905
F6WBK6_CIOIN	F6ZZ65_CIOIN	ENSCINP00000019082	ENSCINP00000012520	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.982
F6WBK6_CIOIN	H2XPG0_CIOIN	ENSCINP00000019082	ENSCINP00000031543	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.558
F6WBK6_CIOIN	H2XRJ0_CIOIN	ENSCINP00000019082	ENSCINP00000032274	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.498
F6WBK6_CIOIN	H2XSR0_CIOIN	ENSCINP00000019082	ENSCINP00000032694	TPR_REGION domain-containing protein.	BTB domain-containing protein.	0.498
F6WBK6_CIOIN	H2XVI1_CIOIN	ENSCINP00000019082	ENSCINP00000033665	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.498
F6WBK6_CIOIN	H2Y1J9_CIOIN	ENSCINP00000019082	ENSCINP00000035783	TPR_REGION domain-containing protein.	BTB domain-containing protein.	0.498
F6WBK6_CIOIN	LOC100184123	ENSCINP00000019082	ENSCINP00000025380	TPR_REGION domain-containing protein.	Bardet-Biedl syndrome 2 protein homolog.	0.970
F6WBK6_CIOIN	Smoothened	ENSCINP00000019082	ENSCINP00000002708	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.548