(21 nodes) Embryonic heart tube morphogenesis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tgfbr-iib	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (567 aa)
	Ci-ZF(ZZ)-7	Zinc finger protein. (619 aa)
	F6UPI8_CIOIN	Fork-head domain-containing protein. (596 aa)
	Smoothened	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
	tbx20	Uncharacterized protein. (437 aa)
	Foxh-a	Fork-head domain-containing protein. (455 aa)
	F6Z6K5_CIOIN	Suppressor of fused homolog. (473 aa)
	LOC100176668	Transmembrane emp24 domain-containing protein 2. (203 aa)
	F6X0V6_CIOIN	Uncharacterized protein. (426 aa)
	F6TQ49_CIOIN	ANK_REP_REGION domain-containing protein. (147 aa)
	tbx2/3	T-box containing transcription factor isoform X2. (803 aa)
	F6YJE0_CIOIN	Uncharacterized protein. (772 aa)
	LOC100184081	Uncharacterized protein. (305 aa)
	LOC778836	Homeobox domain-containing protein. (146 aa)
	LOC100183546	Dynein assembly factor 1, axonemal homolog. (628 aa)
	H2XJG1_CIOIN	RING-type domain-containing protein. (147 aa)
	srf	Transcription factor protein. (335 aa)
	H2XTC3_CIOIN	Fork-head domain-containing protein. (119 aa)
	LOC100175445	Uncharacterized protein. (864 aa)
	H2XWC7_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (170 aa)
	H2XYC7_CIOIN	Uncharacterized protein. (197 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ci-ZF(ZZ)-7	H2XJG1_CIOIN	ENSCINP00000001354	ENSCINP00000029793	Zinc finger protein.	RING-type domain-containing protein.	0.895
F6X0V6_CIOIN	F6Z6K5_CIOIN	ENSCINP00000017470	ENSCINP00000016536	Uncharacterized protein.	Suppressor of fused homolog.	0.562
F6X0V6_CIOIN	H2XWC7_CIOIN	ENSCINP00000017470	ENSCINP00000033961	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.514
F6X0V6_CIOIN	LOC100184081	ENSCINP00000017470	ENSCINP00000027834	Uncharacterized protein.	Uncharacterized protein.	0.987
F6YJE0_CIOIN	H2XWC7_CIOIN	ENSCINP00000022496	ENSCINP00000033961	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.537
F6Z6K5_CIOIN	F6X0V6_CIOIN	ENSCINP00000016536	ENSCINP00000017470	Suppressor of fused homolog.	Uncharacterized protein.	0.562
F6Z6K5_CIOIN	Smoothened	ENSCINP00000016536	ENSCINP00000002708	Suppressor of fused homolog.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.797
H2XJG1_CIOIN	Ci-ZF(ZZ)-7	ENSCINP00000029793	ENSCINP00000001354	RING-type domain-containing protein.	Zinc finger protein.	0.895
H2XWC7_CIOIN	F6X0V6_CIOIN	ENSCINP00000033961	ENSCINP00000017470	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.514
H2XWC7_CIOIN	F6YJE0_CIOIN	ENSCINP00000033961	ENSCINP00000022496	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.537
H2XWC7_CIOIN	Smoothened	ENSCINP00000033961	ENSCINP00000002708	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.481
LOC100175445	LOC100183546	ENSCINP00000033355	ENSCINP00000028025	Uncharacterized protein.	Dynein assembly factor 1, axonemal homolog.	0.509
LOC100183546	LOC100175445	ENSCINP00000028025	ENSCINP00000033355	Dynein assembly factor 1, axonemal homolog.	Uncharacterized protein.	0.509
LOC100184081	F6X0V6_CIOIN	ENSCINP00000027834	ENSCINP00000017470	Uncharacterized protein.	Uncharacterized protein.	0.987
Smoothened	F6Z6K5_CIOIN	ENSCINP00000002708	ENSCINP00000016536	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Suppressor of fused homolog.	0.797
Smoothened	H2XWC7_CIOIN	ENSCINP00000002708	ENSCINP00000033961	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.481
srf	tbx20	ENSCINP00000032435	ENSCINP00000010822	Transcription factor protein.	Uncharacterized protein.	0.480
tbx20	srf	ENSCINP00000010822	ENSCINP00000032435	Uncharacterized protein.	Transcription factor protein.	0.480