17 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6R4H7_CIOIN	Uncharacterized protein. (315 aa)
	F6SIX8_CIOIN	WD_REPEATS_REGION domain-containing protein. (429 aa)
	F7BA18_CIOIN	DNA helicase; Belongs to the MCM family. (740 aa)
	F6TBB0_CIOIN	AAA_16 domain-containing protein. (432 aa)
	LOC100182084	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (461 aa)
	F6RZM2_CIOIN	DNA polymerase. (382 aa)
	F6T368_CIOIN	DNA_pol_B_exo1 domain-containing protein. (276 aa)
	cdc45	Uncharacterized protein. (249 aa)
	F6QND3_CIOIN	Mcm10 domain-containing protein. (755 aa)
	F6UIT3_CIOIN	Uncharacterized protein. (162 aa)
	F6X3C5_CIOIN	HA2 domain-containing protein. (413 aa)
	F6X3A4_CIOIN	Uncharacterized protein. (594 aa)
	F6W6L5_CIOIN	MCM domain-containing protein; Belongs to the MCM family. (422 aa)
	F6W685_CIOIN	Uncharacterized protein. (428 aa)
	LOC100183401	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (426 aa)
	H2XRL5_CIOIN	zf-DNA_Pol domain-containing protein. (143 aa)
	H2XNL8_CIOIN	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (419 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QND3_CIOIN	F6R4H7_CIOIN	ENSCINP00000009731	ENSCINP00000004858	Mcm10 domain-containing protein.	Uncharacterized protein.	0.973
F6QND3_CIOIN	F6RZM2_CIOIN	ENSCINP00000009731	ENSCINP00000003220	Mcm10 domain-containing protein.	DNA polymerase.	0.765
F6QND3_CIOIN	F6T368_CIOIN	ENSCINP00000009731	ENSCINP00000029299	Mcm10 domain-containing protein.	DNA_pol_B_exo1 domain-containing protein.	0.763
F6QND3_CIOIN	F6TBB0_CIOIN	ENSCINP00000009731	ENSCINP00000006804	Mcm10 domain-containing protein.	AAA_16 domain-containing protein.	0.889
F6QND3_CIOIN	F6UIT3_CIOIN	ENSCINP00000009731	ENSCINP00000010855	Mcm10 domain-containing protein.	Uncharacterized protein.	0.967
F6QND3_CIOIN	F6W685_CIOIN	ENSCINP00000009731	ENSCINP00000016062	Mcm10 domain-containing protein.	Uncharacterized protein.	0.959
F6QND3_CIOIN	F6W6L5_CIOIN	ENSCINP00000009731	ENSCINP00000016059	Mcm10 domain-containing protein.	MCM domain-containing protein; Belongs to the MCM family.	0.959
F6QND3_CIOIN	F7BA18_CIOIN	ENSCINP00000009731	ENSCINP00000006895	Mcm10 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.982
F6QND3_CIOIN	H2XNL8_CIOIN	ENSCINP00000009731	ENSCINP00000031251	Mcm10 domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.918
F6QND3_CIOIN	H2XRL5_CIOIN	ENSCINP00000009731	ENSCINP00000032299	Mcm10 domain-containing protein.	zf-DNA_Pol domain-containing protein.	0.765
F6QND3_CIOIN	LOC100182084	ENSCINP00000009731	ENSCINP00000003393	Mcm10 domain-containing protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.991
F6QND3_CIOIN	LOC100183401	ENSCINP00000009731	ENSCINP00000022958	Mcm10 domain-containing protein.	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.920
F6QND3_CIOIN	cdc45	ENSCINP00000009731	ENSCINP00000032459	Mcm10 domain-containing protein.	Uncharacterized protein.	0.967
F6R4H7_CIOIN	F6QND3_CIOIN	ENSCINP00000004858	ENSCINP00000009731	Uncharacterized protein.	Mcm10 domain-containing protein.	0.973
F6R4H7_CIOIN	F6RZM2_CIOIN	ENSCINP00000004858	ENSCINP00000003220	Uncharacterized protein.	DNA polymerase.	0.620
F6R4H7_CIOIN	F6T368_CIOIN	ENSCINP00000004858	ENSCINP00000029299	Uncharacterized protein.	DNA_pol_B_exo1 domain-containing protein.	0.616
F6R4H7_CIOIN	F6TBB0_CIOIN	ENSCINP00000004858	ENSCINP00000006804	Uncharacterized protein.	AAA_16 domain-containing protein.	0.999
F6R4H7_CIOIN	F6UIT3_CIOIN	ENSCINP00000004858	ENSCINP00000010855	Uncharacterized protein.	Uncharacterized protein.	0.894
F6R4H7_CIOIN	F6W685_CIOIN	ENSCINP00000004858	ENSCINP00000016062	Uncharacterized protein.	Uncharacterized protein.	0.960
F6R4H7_CIOIN	F6W6L5_CIOIN	ENSCINP00000004858	ENSCINP00000016059	Uncharacterized protein.	MCM domain-containing protein; Belongs to the MCM family.	0.960