(56 nodes) Cysteine-type endopeptidase activity network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100185957	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1. (624 aa)
	F6SGI6_CIOIN	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (734 aa)
	F6W768_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (390 aa)
	F6SW20_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (436 aa)
	F6Z3D0_CIOIN	Uncharacterized protein; Belongs to the peptidase C1 family. (338 aa)
	F6RZT0_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (262 aa)
	F7AAB5_CIOIN	Uncharacterized protein. (224 aa)
	F7AA12_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (92 aa)
	F7AIX9_CIOIN	Uncharacterized protein. (402 aa)
	F6YDR3_CIOIN	Uncharacterized protein. (446 aa)
	F6TBE2_CIOIN	Uncharacterized protein. (444 aa)
	LOC100179627	Uncharacterized protein LOC100179627 isoform X2; Belongs to the peptidase C14A family. (526 aa)
	F6XGS0_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	F6YGJ7_CIOIN	Uncharacterized protein; Belongs to the peptidase C19 family. (1099 aa)
	F6TZD9_CIOIN	Uncharacterized protein; Belongs to the peptidase C2 family. (673 aa)
	F7AQS5_CIOIN	Peptidase C50 domain-containing protein. (234 aa)
	LOC104265788	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (199 aa)
	F6XEB9_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (260 aa)
	LOC100175572	Caspase-3-like isoform X1; Belongs to the peptidase C14A family. (375 aa)
	LOC100176909	Ubiquitin carboxyl-terminal hydrolase 10-like; Belongs to the peptidase C19 family. (714 aa)
	F7AGM4_CIOIN	calpain_III domain-containing protein. (98 aa)
	Zf(ubp)-1	Ubiquitin carboxyl-terminal hydrolase. (825 aa)
	F6ZVH3_CIOIN	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (651 aa)
	F6S8C9_CIOIN	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (122 aa)
	F6XYE9_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (319 aa)
	F7AMH7_CIOIN	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (410 aa)
	LOC100187119	Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
	LOC100179909	Uncharacterized protein; Belongs to the peptidase C1 family. (341 aa)
	LOC100176092	Cathepsin L1-like isoform X3; Belongs to the peptidase C1 family. (327 aa)
	LOC100176092-2	Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (330 aa)
	LOC100183329	ULP_PROTEASE domain-containing protein. (387 aa)
	LOC100176021	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (407 aa)
	F6PIY0_CIOIN	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (257 aa)
	F6WXG6_CIOIN	Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
	F6PIR1_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (151 aa)
	LOC100185968	Caspase-6-like isoform X1; Belongs to the peptidase C14A family. (279 aa)
	F6YVN9_CIOIN	Ubiquitin carboxyl-terminal hydrolase. (585 aa)
	F6QRQ7_CIOIN	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (238 aa)
	F7A844_CIOIN	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (187 aa)
	LOC100175951	Ubiquitin carboxyl-terminal hydrolase. (423 aa)
	F6YS31_CIOIN	Uncharacterized protein. (297 aa)
	F6U351_CIOIN	Uncharacterized protein; Belongs to the peptidase C14A family. (259 aa)
	LOC100186187	Ubiquitin carboxyl-terminal hydrolase 37; Belongs to the peptidase C19 family. (635 aa)
	LOC100182411	WD_REPEATS_REGION domain-containing protein. (294 aa)
	H2XN11_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (336 aa)
	H2XP77_CIOIN	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (206 aa)
	H2XPN2_CIOIN	DUF4203 domain-containing protein. (51 aa)
	H2XQF8_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (231 aa)
	H2XR46_CIOIN	Uncharacterized protein. (617 aa)
	H2XR85_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (1053 aa)
	H2XSW0_CIOIN	USP domain-containing protein. (288 aa)
	H2XU19_CIOIN	Uncharacterized protein. (368 aa)
	H2XX31_CIOIN	Uncharacterized protein. (366 aa)
	H2XYD4_CIOIN	Uncharacterized protein. (216 aa)
	H2Y1S8_CIOIN	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (162 aa)
	H2Y345_CIOIN	Uncharacterized protein. (214 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PIR1_CIOIN	F6YVN9_CIOIN	ENSCINP00000020217	ENSCINP00000024812	USP domain-containing protein; Belongs to the peptidase C19 family.	Ubiquitin carboxyl-terminal hydrolase.	0.602
F6PIR1_CIOIN	Zf(ubp)-1	ENSCINP00000020217	ENSCINP00000014360	USP domain-containing protein; Belongs to the peptidase C19 family.	Ubiquitin carboxyl-terminal hydrolase.	0.702
F6RZT0_CIOIN	H2Y1S8_CIOIN	ENSCINP00000003207	ENSCINP00000035862	Uncharacterized protein; Belongs to the peptidase C14A family.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.565
F6SW20_CIOIN	H2Y1S8_CIOIN	ENSCINP00000002956	ENSCINP00000035862	Uncharacterized protein; Belongs to the peptidase C14A family.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.420
F6TBE2_CIOIN	F6WXG6_CIOIN	ENSCINP00000006801	ENSCINP00000019058	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.423
F6TBE2_CIOIN	F6Z3D0_CIOIN	ENSCINP00000006801	ENSCINP00000003040	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.699
F6TBE2_CIOIN	F7AQS5_CIOIN	ENSCINP00000006801	ENSCINP00000010143	Uncharacterized protein.	Peptidase C50 domain-containing protein.	0.618
F6TBE2_CIOIN	H2XP77_CIOIN	ENSCINP00000006801	ENSCINP00000031460	Uncharacterized protein.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.785
F6TBE2_CIOIN	LOC100176092	ENSCINP00000006801	ENSCINP00000015736	Uncharacterized protein.	Cathepsin L1-like isoform X3; Belongs to the peptidase C1 family.	0.410
F6TBE2_CIOIN	LOC100176092-2	ENSCINP00000006801	ENSCINP00000015737	Uncharacterized protein.	Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family.	0.410
F6TBE2_CIOIN	LOC100179909	ENSCINP00000006801	ENSCINP00000015731	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.410
F6TBE2_CIOIN	LOC100187119	ENSCINP00000006801	ENSCINP00000015724	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.410
F6U351_CIOIN	H2Y1S8_CIOIN	ENSCINP00000028693	ENSCINP00000035862	Uncharacterized protein; Belongs to the peptidase C14A family.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.566
F6W768_CIOIN	H2Y1S8_CIOIN	ENSCINP00000002830	ENSCINP00000035862	Uncharacterized protein; Belongs to the peptidase C14A family.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.462
F6WXG6_CIOIN	F6TBE2_CIOIN	ENSCINP00000019058	ENSCINP00000006801	Uncharacterized protein; Belongs to the peptidase C1 family.	Uncharacterized protein.	0.423
F6WXG6_CIOIN	F6Z3D0_CIOIN	ENSCINP00000019058	ENSCINP00000003040	Uncharacterized protein; Belongs to the peptidase C1 family.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.945
F6WXG6_CIOIN	H2XP77_CIOIN	ENSCINP00000019058	ENSCINP00000031460	Uncharacterized protein; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.949
F6WXG6_CIOIN	LOC100176092	ENSCINP00000019058	ENSCINP00000015736	Uncharacterized protein; Belongs to the peptidase C1 family.	Cathepsin L1-like isoform X3; Belongs to the peptidase C1 family.	0.922
F6WXG6_CIOIN	LOC100179909	ENSCINP00000019058	ENSCINP00000015731	Uncharacterized protein; Belongs to the peptidase C1 family.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.922
F6WXG6_CIOIN	LOC100187119	ENSCINP00000019058	ENSCINP00000015724	Uncharacterized protein; Belongs to the peptidase C1 family.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.922