13 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	LOC100185308	Sm domain-containing protein. (173 aa)
	F7AK99_CIOIN	Uncharacterized protein; Belongs to the AAA ATPase family. (696 aa)
	F6Y8C3_CIOIN	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (956 aa)
	F6U2M6_CIOIN	PUA domain-containing protein. (528 aa)
	F6R982_CIOIN	WD_REPEATS_REGION domain-containing protein. (433 aa)
	LOC100181113	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (198 aa)
	F6V093_CIOIN	Uncharacterized protein. (325 aa)
	F6WCU4_CIOIN	Uncharacterized protein. (954 aa)
	LOC100187276	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (904 aa)
	F6PIQ0_CIOIN	PINc domain-containing protein. (485 aa)
	H2XS48_CIOIN	TROVE domain-containing protein. (331 aa)
	H2Y3J0_CIOIN	Uncharacterized protein. (176 aa)
	H2Y3R0_CIOIN	Uncharacterized protein. (173 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PIQ0_CIOIN	F6V093_CIOIN	ENSCINP00000020219	ENSCINP00000014270	PINc domain-containing protein.	Uncharacterized protein.	0.875
F6PIQ0_CIOIN	F6WCU4_CIOIN	ENSCINP00000020219	ENSCINP00000017766	PINc domain-containing protein.	Uncharacterized protein.	0.894
F6PIQ0_CIOIN	H2XS48_CIOIN	ENSCINP00000020219	ENSCINP00000032482	PINc domain-containing protein.	TROVE domain-containing protein.	0.556
F6PIQ0_CIOIN	H2Y3J0_CIOIN	ENSCINP00000020219	ENSCINP00000036475	PINc domain-containing protein.	Uncharacterized protein.	0.961
F6PIQ0_CIOIN	LOC100187276	ENSCINP00000020219	ENSCINP00000018420	PINc domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.818
F6R982_CIOIN	F6U2M6_CIOIN	ENSCINP00000009975	ENSCINP00000009502	WD_REPEATS_REGION domain-containing protein.	PUA domain-containing protein.	0.972
F6R982_CIOIN	LOC100181113	ENSCINP00000009975	ENSCINP00000011858	WD_REPEATS_REGION domain-containing protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.956
F6R982_CIOIN	LOC100187276	ENSCINP00000009975	ENSCINP00000018420	WD_REPEATS_REGION domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.863
F6U2M6_CIOIN	F6R982_CIOIN	ENSCINP00000009502	ENSCINP00000009975	PUA domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.972
F6U2M6_CIOIN	F6Y8C3_CIOIN	ENSCINP00000009502	ENSCINP00000007371	PUA domain-containing protein.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.944
F6U2M6_CIOIN	LOC100181113	ENSCINP00000009502	ENSCINP00000011858	PUA domain-containing protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
F6U2M6_CIOIN	LOC100187276	ENSCINP00000009502	ENSCINP00000018420	PUA domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.895
F6V093_CIOIN	F6PIQ0_CIOIN	ENSCINP00000014270	ENSCINP00000020219	Uncharacterized protein.	PINc domain-containing protein.	0.875
F6V093_CIOIN	F6WCU4_CIOIN	ENSCINP00000014270	ENSCINP00000017766	Uncharacterized protein.	Uncharacterized protein.	0.950
F6V093_CIOIN	H2XS48_CIOIN	ENSCINP00000014270	ENSCINP00000032482	Uncharacterized protein.	TROVE domain-containing protein.	0.556
F6V093_CIOIN	H2Y3J0_CIOIN	ENSCINP00000014270	ENSCINP00000036475	Uncharacterized protein.	Uncharacterized protein.	0.875
F6V093_CIOIN	LOC100187276	ENSCINP00000014270	ENSCINP00000018420	Uncharacterized protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.807
F6WCU4_CIOIN	F6PIQ0_CIOIN	ENSCINP00000017766	ENSCINP00000020219	Uncharacterized protein.	PINc domain-containing protein.	0.894
F6WCU4_CIOIN	F6V093_CIOIN	ENSCINP00000017766	ENSCINP00000014270	Uncharacterized protein.	Uncharacterized protein.	0.950
F6WCU4_CIOIN	H2XS48_CIOIN	ENSCINP00000017766	ENSCINP00000032482	Uncharacterized protein.	TROVE domain-containing protein.	0.556