STRINGSTRING
H2XYU0_CIOIN H2XYU0_CIOIN H2XZ35_CIOIN H2XZ35_CIOIN H2XZM3_CIOIN H2XZM3_CIOIN H2XZT6_CIOIN H2XZT6_CIOIN LOC100176801 LOC100176801 H2Y0C0_CIOIN H2Y0C0_CIOIN H2Y1G1_CIOIN H2Y1G1_CIOIN LOC100185883 LOC100185883 LOC100184027 LOC100184027 LOC100184275 LOC100184275 LOC100179457 LOC100179457 LOC100183355 LOC100183355 F6QVW6_CIOIN F6QVW6_CIOIN F7AFH3_CIOIN F7AFH3_CIOIN LOC100184601 LOC100184601 LOC100176240 LOC100176240 LOC100186307 LOC100186307 F6X4A8_CIOIN F6X4A8_CIOIN LOC100185737 LOC100185737 LOC100185868 LOC100185868 F6SZY0_CIOIN F6SZY0_CIOIN F6WNV4_CIOIN F6WNV4_CIOIN F6ZME6_CIOIN F6ZME6_CIOIN F6Y8C3_CIOIN F6Y8C3_CIOIN F6XJG1_CIOIN F6XJG1_CIOIN F6U6C0_CIOIN F6U6C0_CIOIN F6Y4T9_CIOIN F6Y4T9_CIOIN LOC100181797 LOC100181797 LOC100183289 LOC100183289 F6YGW9_CIOIN F6YGW9_CIOIN F6V9G2_CIOIN F6V9G2_CIOIN F6U2M6_CIOIN F6U2M6_CIOIN LOC100176504 LOC100176504 LOC100186181 LOC100186181 LOC113473990 LOC113473990 F6TFE2_CIOIN F6TFE2_CIOIN LOC100182144 LOC100182144 LOC100181113 LOC100181113 F6YVG2_CIOIN F6YVG2_CIOIN F6Q4L9_CIOIN F6Q4L9_CIOIN F6QPL4_CIOIN F6QPL4_CIOIN LOC100186678 LOC100186678 LOC100184413 LOC100184413 F6SV73_CIOIN F6SV73_CIOIN LOC100181090 LOC100181090 F6XWW8_CIOIN F6XWW8_CIOIN F6XTM9_CIOIN F6XTM9_CIOIN LOC100181071 LOC100181071 F7A1S8_CIOIN F7A1S8_CIOIN LOC100181991 LOC100181991 LOC100175025 LOC100175025 F6YCY6_CIOIN F6YCY6_CIOIN LOC100179078 LOC100179078 F6Q9C5_CIOIN F6Q9C5_CIOIN F6WN37_CIOIN F6WN37_CIOIN F6TLE4_CIOIN F6TLE4_CIOIN F7AZ70_CIOIN F7AZ70_CIOIN F7AZ63_CIOIN F7AZ63_CIOIN F6XKA2_CIOIN F6XKA2_CIOIN F6TJ71_CIOIN F6TJ71_CIOIN F6ZTX9_CIOIN F6ZTX9_CIOIN F6Y5N8_CIOIN F6Y5N8_CIOIN LOC100184403 LOC100184403 zf(c3h)-5 zf(c3h)-5 F6UXU4_CIOIN F6UXU4_CIOIN F6U8L4_CIOIN F6U8L4_CIOIN F6TU78_CIOIN F6TU78_CIOIN F7AUU8_CIOIN F7AUU8_CIOIN F6PZV6_CIOIN F6PZV6_CIOIN F6PZD7_CIOIN F6PZD7_CIOIN F7BMW8_CIOIN F7BMW8_CIOIN F6YYA5_CIOIN F6YYA5_CIOIN F6UFW3_CIOIN F6UFW3_CIOIN F6SGC2_CIOIN F6SGC2_CIOIN LOC100186777 LOC100186777 LOC100177511 LOC100177511 F6YVJ9_CIOIN F6YVJ9_CIOIN LOC100180306 LOC100180306 H2Y3I7_CIOIN H2Y3I7_CIOIN TRM5_CIOIN TRM5_CIOIN F6V1A9_CIOIN F6V1A9_CIOIN F6PXD8_CIOIN F6PXD8_CIOIN F6QG58_CIOIN F6QG58_CIOIN LOC100177644 LOC100177644 LOC100181974 LOC100181974 F7A7B2_CIOIN F7A7B2_CIOIN F6YB51_CIOIN F6YB51_CIOIN F6YB44_CIOIN F6YB44_CIOIN F6XLM7_CIOIN F6XLM7_CIOIN LOC100178784 LOC100178784 LOC100184342 LOC100184342 F6YNA8_CIOIN F6YNA8_CIOIN F6X1E1_CIOIN F6X1E1_CIOIN F6ZY66_CIOIN F6ZY66_CIOIN H2XJI9_CIOIN H2XJI9_CIOIN H2XK08_CIOIN H2XK08_CIOIN LOC100175302 LOC100175302 H2XKP3_CIOIN H2XKP3_CIOIN H2XKW2_CIOIN H2XKW2_CIOIN LOC100176337 LOC100176337 H2XNI6_CIOIN H2XNI6_CIOIN H2XP61_CIOIN H2XP61_CIOIN H2XP93_CIOIN H2XP93_CIOIN H2XPN1_CIOIN H2XPN1_CIOIN H2XPP0_CIOIN H2XPP0_CIOIN LOC100180291 LOC100180291 H2XQE4_CIOIN H2XQE4_CIOIN H2XQZ0_CIOIN H2XQZ0_CIOIN H2XRA6_CIOIN H2XRA6_CIOIN H2XRH2_CIOIN H2XRH2_CIOIN H2XS72_CIOIN H2XS72_CIOIN LOC100187478 LOC100187478 H2XSX6_CIOIN H2XSX6_CIOIN H2XTN4_CIOIN H2XTN4_CIOIN H2XVE9_CIOIN H2XVE9_CIOIN H2XVW4_CIOIN H2XVW4_CIOIN H2XVY6_CIOIN H2XVY6_CIOIN H2XWZ3_CIOIN H2XWZ3_CIOIN H2XX92_CIOIN H2XX92_CIOIN H2XXY6_CIOIN H2XXY6_CIOIN LOC100180383 LOC100180383
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2XYU0_CIOINUncharacterized protein. (243 aa)
H2XZ35_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (423 aa)
H2XZM3_CIOINCytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (344 aa)
H2XZT6_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (682 aa)
LOC100176801Multifunctional methyltransferase subunit TRM112-like protein. (131 aa)
H2Y0C0_CIOINSAM_MT_TRM5_TYW2 domain-containing protein. (299 aa)
H2Y1G1_CIOINUncharacterized protein. (162 aa)
LOC100185883alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (967 aa)
LOC100184027mRNA cap guanine-N7 methyltransferase. (398 aa)
LOC100184275DTW domain-containing protein 2-like isoform X1. (227 aa)
LOC100179457methionyl-tRNA formyltransferase, mitochondrial. (336 aa)
LOC100183355Uncharacterized protein. (496 aa)
F6QVW6_CIOINUncharacterized protein. (319 aa)
F7AFH3_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (141 aa)
LOC100184601Methyltransferase-like protein 5 isoform X4. (214 aa)
LOC100176240N6-adenosine-methyltransferase non-catalytic subunit-like; Belongs to the MT-A70-like family. (474 aa)
LOC100186307tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (309 aa)
F6X4A8_CIOINUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (262 aa)
LOC100185737Uncharacterized protein. (403 aa)
LOC100185868DTW domain-containing protein 1. (262 aa)
F6SZY0_CIOINtRNA (guanine(26)-N(2))-dimethyltransferase. (560 aa)
F6WNV4_CIOINUPF0020 domain-containing protein. (193 aa)
F6ZME6_CIOINUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)
F6Y8C3_CIOINRNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (956 aa)
F6XJG1_CIOINUncharacterized protein. (325 aa)
F6U6C0_CIOINPseudoU_synth_2 domain-containing protein. (339 aa)
F6Y4T9_CIOINUncharacterized protein. (627 aa)
LOC100181797rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (384 aa)
LOC100183289tRNA (Cytosine(38)-C(5))-methyltransferase-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (343 aa)
F6YGW9_CIOINUncharacterized protein. (561 aa)
F6V9G2_CIOINFlavodoxin-like domain-containing protein. (558 aa)
F6U2M6_CIOINPUA domain-containing protein. (528 aa)
LOC100176504Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1284 aa)
LOC100186181rRNA 2'-O-methyltransferase fibrillarin. (308 aa)
LOC113473990RRM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (590 aa)
F6TFE2_CIOINUncharacterized protein. (283 aa)
LOC100182144Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (550 aa)
LOC100181113H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (198 aa)
F6YVG2_CIOINSpoU_methylase domain-containing protein. (259 aa)
F6Q4L9_CIOINCytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (395 aa)
F6QPL4_CIOINUncharacterized protein. (286 aa)
LOC100186678Serine/arginine repetitive matrix protein 1-like isoform X2. (1124 aa)
LOC100184413TRUD domain-containing protein. (423 aa)
F6SV73_CIOINSAM-dependent MTase TRM10-type domain-containing protein. (263 aa)
LOC100181090Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (276 aa)
F6XWW8_CIOINUncharacterized protein. (452 aa)
F6XTM9_CIOINFe2OG dioxygenase domain-containing protein. (154 aa)
LOC100181071TRUD domain-containing protein. (596 aa)
F7A1S8_CIOINAdenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] (410 aa)
LOC100181991tRNA wybutosine-synthesizing protein 4. (690 aa)
LOC100175025Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (322 aa)
F6YCY6_CIOINMethyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (320 aa)
LOC100179078tRNA pseudouridine(38/39) synthase. (510 aa)
F6Q9C5_CIOINUncharacterized protein. (762 aa)
F6WN37_CIOINUncharacterized protein. (114 aa)
F6TLE4_CIOINPseudoU_synth_1 domain-containing protein. (371 aa)
F7AZ70_CIOINBin3-type SAM domain-containing protein. (159 aa)
F7AZ63_CIOINUncharacterized protein. (189 aa)
F6XKA2_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (654 aa)
F6TJ71_CIOINUncharacterized protein. (558 aa)
F6ZTX9_CIOINFe2OG dioxygenase domain-containing protein. (603 aa)
F6Y5N8_CIOINC3H1-type domain-containing protein. (479 aa)
LOC100184403Uncharacterized protein. (237 aa)
zf(c3h)-5tRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (609 aa)
F6UXU4_CIOINUncharacterized protein. (217 aa)
F6U8L4_CIOINTsaA-like domain-containing protein. (165 aa)
F6TU78_CIOINDUF2431 domain-containing protein. (203 aa)
F7AUU8_CIOINYrdC-like domain-containing protein. (215 aa)
F6PZV6_CIOINMethyltranfer_dom domain-containing protein. (518 aa)
F6PZD7_CIOINHflx-type G domain-containing protein. (519 aa)
F7BMW8_CIOINAdrift-type SAM-dependent 2'-O-MTase domain-containing protein. (260 aa)
F6YYA5_CIOINtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (251 aa)
F6UFW3_CIOINUncharacterized protein; Belongs to the MT-A70-like family. (204 aa)
F6SGC2_CIOINUncharacterized protein. (292 aa)
LOC100186777ANK_REP_REGION domain-containing protein. (335 aa)
LOC100177511Queuosine salvage protein; Involved in salvaging queuosine. (349 aa)
F6YVJ9_CIOINVIR_N domain-containing protein. (202 aa)
LOC100180306Uncharacterized protein. (220 aa)
H2Y3I7_CIOINUncharacterized protein. (72 aa)
TRM5_CIOINtRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family. (466 aa)
F6V1A9_CIOINUncharacterized protein. (353 aa)
F6PXD8_CIOINUncharacterized protein. (283 aa)
F6QG58_CIOINFtsJ domain-containing protein. (202 aa)
LOC100177644DUF1907 domain-containing protein. (317 aa)
LOC100181974WD repeat-containing protein 6-like. (158 aa)
F7A7B2_CIOINUncharacterized protein. (288 aa)
F6YB51_CIOINDUF2428 domain-containing protein. (372 aa)
F6YB44_CIOINUncharacterized protein. (352 aa)
F6XLM7_CIOINDALR_1 domain-containing protein. (140 aa)
LOC100178784Peptidase_M22 domain-containing protein. (395 aa)
LOC100184342Protein KTI12 homolog. (274 aa)
F6YNA8_CIOINUncharacterized protein. (168 aa)
F6X1E1_CIOINUPF0020 domain-containing protein. (456 aa)
F6ZY66_CIOINUncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (240 aa)
H2XJI9_CIOINQueuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (336 aa)
H2XK08_CIOINTGT domain-containing protein. (38 aa)
LOC100175302CDK5 regulatory subunit-associated protein 1. (618 aa)
H2XKP3_CIOINA to I editase domain-containing protein. (177 aa)
H2XKW2_CIOINGIDA_assoc domain-containing protein. (637 aa)
LOC100176337EKC/KEOPS complex subunit TPRKB; Belongs to the CGI121/TPRKB family. (171 aa)
H2XNI6_CIOINUncharacterized protein. (477 aa)
H2XP61_CIOINH/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (236 aa)
H2XP93_CIOINUncharacterized protein. (379 aa)
H2XPN1_CIOINDRBM domain-containing protein. (117 aa)
H2XPP0_CIOINDRBM domain-containing protein. (194 aa)
LOC100180291EF-hand calcium-binding domain-containing protein 14. (441 aa)
H2XQE4_CIOINProbable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (340 aa)
H2XQZ0_CIOINUncharacterized protein. (193 aa)
H2XRA6_CIOINUncharacterized protein. (142 aa)
H2XRH2_CIOINUncharacterized protein. (790 aa)
H2XS72_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (378 aa)
LOC100187478dnaJ homolog subfamily B member 11-like. (360 aa)
H2XSX6_CIOINtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (303 aa)
H2XTN4_CIOINPfkB domain-containing protein. (674 aa)
H2XVE9_CIOINJmjC domain-containing protein. (313 aa)
H2XVW4_CIOINAA_TRNA_LIGASE_II_ALA domain-containing protein. (609 aa)
H2XVY6_CIOINUncharacterized protein. (178 aa)
H2XWZ3_CIOINPutative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (736 aa)
H2XX92_CIOINUncharacterized protein. (393 aa)
H2XXY6_CIOINTHUMP domain-containing protein. (283 aa)
LOC100180383tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (264 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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