(55 nodes) Cytoplasmic side of plasma membrane network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F7A9G9_CIOIN	RING-type domain-containing protein. (966 aa)
	gi1	G protein alpha subunit Gi splicing variant CiGi1a. (354 aa)
	F6UNA9_CIOIN	Sec3_C domain-containing protein. (314 aa)
	F6UMZ6_CIOIN	Uncharacterized protein. (360 aa)
	LOC100182745	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (347 aa)
	LOC100185034	Sterile alpha motif domain-containing protein 12-like isoform X1. (181 aa)
	F6PIA1_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (277 aa)
	F6SZF9_CIOIN	Phorbol-ester/DAG-type domain-containing protein. (219 aa)
	F6QTW3_CIOIN	Tyrosine-protein kinase. (626 aa)
	F6XQ39_CIOIN	Uncharacterized protein. (199 aa)
	F6XP43_CIOIN	Tyrosine-protein kinase. (467 aa)
	F6TXB9_CIOIN	Tyrosine-protein kinase. (469 aa)
	LOC445772	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (362 aa)
	F6Z221_CIOIN	UBA domain-containing protein. (215 aa)
	H2Y1Q1_CIOIN	Uncharacterized protein. (356 aa)
	H2Y144_CIOIN	Protein kinase domain-containing protein. (351 aa)
	H2XZT8_CIOIN	Uncharacterized protein. (69 aa)
	H2XYE3_CIOIN	SMP-LTD domain-containing protein. (298 aa)
	H2XXW5_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	H2XWZ8_CIOIN	Uncharacterized protein. (111 aa)
	F6WSD2_CIOIN	BSD domain-containing protein. (400 aa)
	F6VZ78_CIOIN	MATH domain-containing protein. (193 aa)
	F6R1I0_CIOIN	Uncharacterized protein. (362 aa)
	LOC100178481	TNF receptor-associated factor 3. (369 aa)
	F6SGK0_CIOIN	Tyrosine-protein kinase. (954 aa)
	F6WH54_CIOIN	Tyrosine-protein kinase. (471 aa)
	F6PKW3_CIOIN	Tyrosine-protein kinase. (838 aa)
	F6Q8X5_CIOIN	Uncharacterized protein. (449 aa)
	Ptp	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (987 aa)
	F7AS27_CIOIN	IMD domain-containing protein. (565 aa)
	LOC101243377	Migration and invasion enhancer 1. (76 aa)
	H2XRW6_CIOIN	Tyrosine-protein kinase. (412 aa)
	H2XR59_CIOIN	Uncharacterized protein. (489 aa)
	H2XQR3_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	LOC100178442	MATH domain-containing protein. (204 aa)
	H2XPF9_CIOIN	Uncharacterized protein. (119 aa)
	H2XP47_CIOIN	G protein gamma domain-containing protein. (68 aa)
	LOC100187429	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (160 aa)
	F6WUP4_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
	LOC100184799	Tyrosine-protein kinase. (508 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	LOC100185572	Charged multivesicular body protein 4b-like isoform X1. (217 aa)
	F7A141_CIOIN	Protein kinase domain-containing protein. (275 aa)
	LOC100181387	Magnesium-dependent phosphatase 1-like. (168 aa)
	LOC100179623	TNF receptor-associated factor 3-like isoform X1. (351 aa)
	F7AX62_CIOIN	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (482 aa)
	F6RD62_CIOIN	Uncharacterized protein. (377 aa)
	F6PR32_CIOIN	Uncharacterized protein. (354 aa)
	F6ZBN8_CIOIN	CAP-Gly domain-containing protein. (292 aa)
	F6S8T2_CIOIN	Protein kinase domain-containing protein. (369 aa)
	LOC100183015	Tyrosine-protein kinase. (472 aa)
	LOC100185405	Guanine nucleotide-binding protein G(S) subunit alpha-like. (381 aa)
	LOC104266020	Uncharacterized protein. (168 aa)
	F6PHM0_CIOIN	Uncharacterized protein. (498 aa)
	LOC100184576	TNF receptor-associated factor 3-like. (290 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PHM0_CIOIN	F6VZ78_CIOIN	ENSCINP00000006295	ENSCINP00000003143	Uncharacterized protein.	MATH domain-containing protein.	0.432
F6PHM0_CIOIN	F7A9G9_CIOIN	ENSCINP00000006295	ENSCINP00000009356	Uncharacterized protein.	RING-type domain-containing protein.	0.791
F6PHM0_CIOIN	LOC100178442	ENSCINP00000006295	ENSCINP00000031812	Uncharacterized protein.	MATH domain-containing protein.	0.432
F6PHM0_CIOIN	LOC100178481	ENSCINP00000006295	ENSCINP00000001022	Uncharacterized protein.	TNF receptor-associated factor 3.	0.432
F6PHM0_CIOIN	LOC100179623	ENSCINP00000006295	ENSCINP00000027890	Uncharacterized protein.	TNF receptor-associated factor 3-like isoform X1.	0.432
F6PHM0_CIOIN	LOC100184576	ENSCINP00000006295	ENSCINP00000005981	Uncharacterized protein.	TNF receptor-associated factor 3-like.	0.432
F6PHM0_CIOIN	Q1RPY5_CIOIN	ENSCINP00000006295	ENSCINP00000030768	Uncharacterized protein.	Zinc finger protein.	0.827
F6PIA1_CIOIN	F6PKW3_CIOIN	ENSCINP00000020254	ENSCINP00000018233	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.401
F6PIA1_CIOIN	F6QTW3_CIOIN	ENSCINP00000020254	ENSCINP00000016885	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.481
F6PIA1_CIOIN	F6WUP4_CIOIN	ENSCINP00000020254	ENSCINP00000007661	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.554
F6PKW3_CIOIN	F6PIA1_CIOIN	ENSCINP00000018233	ENSCINP00000020254	Tyrosine-protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.401
F6PKW3_CIOIN	F6TXB9_CIOIN	ENSCINP00000018233	ENSCINP00000008019	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.429
F6PKW3_CIOIN	F6WH54_CIOIN	ENSCINP00000018233	ENSCINP00000012004	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.416
F6PKW3_CIOIN	F6XP43_CIOIN	ENSCINP00000018233	ENSCINP00000017456	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.432
F6PKW3_CIOIN	LOC100183015	ENSCINP00000018233	ENSCINP00000011940	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.415
F6PKW3_CIOIN	LOC100184799	ENSCINP00000018233	ENSCINP00000031420	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.415
F6PR32_CIOIN	F6R1I0_CIOIN	ENSCINP00000013090	ENSCINP00000001526	Uncharacterized protein.	Uncharacterized protein.	0.594
F6PR32_CIOIN	F6RD62_CIOIN	ENSCINP00000013090	ENSCINP00000006303	Uncharacterized protein.	Uncharacterized protein.	0.591
F6PR32_CIOIN	H2XP47_CIOIN	ENSCINP00000013090	ENSCINP00000031430	Uncharacterized protein.	G protein gamma domain-containing protein.	0.819
F6PR32_CIOIN	H2XQR3_CIOIN	ENSCINP00000013090	ENSCINP00000031997	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.833