(17 nodes) Histone monoubiquitination network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6SQ79_CIOIN	RING-type domain-containing protein. (190 aa)
	zf(ring)-23	RING-type domain-containing protein. (319 aa)
	F6ZAH0_CIOIN	Uncharacterized protein. (382 aa)
	F6TZN8_CIOIN	WW domain-containing protein. (437 aa)
	LOC100175816	TPR_REGION domain-containing protein. (1034 aa)
	LOC494392	Uncharacterized protein LOC494392. (131 aa)
	F7ANR5_CIOIN	CPSF_A domain-containing protein. (1145 aa)
	F6RG85_CIOIN	RING-type domain-containing protein. (248 aa)
	F6SQA2_CIOIN	DTC domain-containing protein. (81 aa)
	F6SQE1_CIOIN	Uncharacterized protein. (651 aa)
	F6ZZ26_CIOIN	RING-type domain-containing protein. (269 aa)
	F6SEM6_CIOIN	SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (256 aa)
	H2XLG0_CIOIN	RING-type domain-containing protein. (354 aa)
	H2XLZ0_CIOIN	RING-type domain-containing protein. (223 aa)
	H2XM66_CIOIN	E3 ubiquitin protein ligase. (985 aa)
	H2XUU5_CIOIN	Uncharacterized protein. (532 aa)
	LOC104265921	E3 ubiquitin protein ligase. (208 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6RG85_CIOIN	F6ZZ26_CIOIN	ENSCINP00000009676	ENSCINP00000005674	RING-type domain-containing protein.	RING-type domain-containing protein.	0.594
F6RG85_CIOIN	H2XLG0_CIOIN	ENSCINP00000009676	ENSCINP00000030492	RING-type domain-containing protein.	RING-type domain-containing protein.	0.662
F6RG85_CIOIN	H2XLZ0_CIOIN	ENSCINP00000009676	ENSCINP00000030672	RING-type domain-containing protein.	RING-type domain-containing protein.	0.672
F6TZN8_CIOIN	H2XM66_CIOIN	ENSCINP00000025963	ENSCINP00000030748	WW domain-containing protein.	E3 ubiquitin protein ligase.	0.688
F6TZN8_CIOIN	H2XUU5_CIOIN	ENSCINP00000025963	ENSCINP00000033429	WW domain-containing protein.	Uncharacterized protein.	0.594
F6TZN8_CIOIN	LOC100175816	ENSCINP00000025963	ENSCINP00000018251	WW domain-containing protein.	TPR_REGION domain-containing protein.	0.499
F6TZN8_CIOIN	LOC104265921	ENSCINP00000025963	ENSCINP00000035714	WW domain-containing protein.	E3 ubiquitin protein ligase.	0.655
F6TZN8_CIOIN	LOC494392	ENSCINP00000025963	ENSCINP00000017068	WW domain-containing protein.	Uncharacterized protein LOC494392.	0.905
F6ZZ26_CIOIN	F6RG85_CIOIN	ENSCINP00000005674	ENSCINP00000009676	RING-type domain-containing protein.	RING-type domain-containing protein.	0.594
F6ZZ26_CIOIN	H2XLG0_CIOIN	ENSCINP00000005674	ENSCINP00000030492	RING-type domain-containing protein.	RING-type domain-containing protein.	0.681
F6ZZ26_CIOIN	H2XLZ0_CIOIN	ENSCINP00000005674	ENSCINP00000030672	RING-type domain-containing protein.	RING-type domain-containing protein.	0.689
F7ANR5_CIOIN	H2XUU5_CIOIN	ENSCINP00000015292	ENSCINP00000033429	CPSF_A domain-containing protein.	Uncharacterized protein.	0.469
F7ANR5_CIOIN	LOC100175816	ENSCINP00000015292	ENSCINP00000018251	CPSF_A domain-containing protein.	TPR_REGION domain-containing protein.	0.509
F7ANR5_CIOIN	LOC494392	ENSCINP00000015292	ENSCINP00000017068	CPSF_A domain-containing protein.	Uncharacterized protein LOC494392.	0.983
H2XLG0_CIOIN	F6RG85_CIOIN	ENSCINP00000030492	ENSCINP00000009676	RING-type domain-containing protein.	RING-type domain-containing protein.	0.662
H2XLG0_CIOIN	F6ZZ26_CIOIN	ENSCINP00000030492	ENSCINP00000005674	RING-type domain-containing protein.	RING-type domain-containing protein.	0.681
H2XLG0_CIOIN	H2XLZ0_CIOIN	ENSCINP00000030492	ENSCINP00000030672	RING-type domain-containing protein.	RING-type domain-containing protein.	0.799
H2XLZ0_CIOIN	F6RG85_CIOIN	ENSCINP00000030672	ENSCINP00000009676	RING-type domain-containing protein.	RING-type domain-containing protein.	0.672
H2XLZ0_CIOIN	F6ZZ26_CIOIN	ENSCINP00000030672	ENSCINP00000005674	RING-type domain-containing protein.	RING-type domain-containing protein.	0.689
H2XLZ0_CIOIN	H2XLG0_CIOIN	ENSCINP00000030672	ENSCINP00000030492	RING-type domain-containing protein.	RING-type domain-containing protein.	0.799