(53 nodes) Regulation of epithelial cell migration network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2Y1F5_CIOIN	Fibrinogen C-terminal domain-containing protein. (283 aa)
	LOC100185836	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (196 aa)
	H2Y066_CIOIN	Uncharacterized protein. (361 aa)
	H2XYX1_CIOIN	Uncharacterized protein. (59 aa)
	H2XWT8_CIOIN	Uncharacterized protein. (206 aa)
	H2XV03_CIOIN	Uncharacterized protein. (625 aa)
	H2XSF5_CIOIN	Sulfatase domain-containing protein. (491 aa)
	H2XQ88_CIOIN	Fibrinogen C-terminal domain-containing protein. (331 aa)
	H2XM17_CIOIN	FAT domain-containing protein. (187 aa)
	H2XJG5_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	F7AK80_CIOIN	Uncharacterized protein. (382 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	LOC779004	Transcription factor protein. (553 aa)
	LOC778850	Zinc finger protein. (676 aa)
	F6SLD6_CIOIN	Deacetylase sirtuin-type domain-containing protein. (737 aa)
	F6XLS2_CIOIN	Uncharacterized protein. (745 aa)
	F6Q301_CIOIN	Uncharacterized protein. (237 aa)
	F6V3W8_CIOIN	Uncharacterized protein. (264 aa)
	F7BEW6_CIOIN	Sulfatase domain-containing protein. (260 aa)
	F7AZD3_CIOIN	Glucose-6-phosphate isomerase; Belongs to the GPI family. (232 aa)
	F6WXG6_CIOIN	Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
	F6R265_CIOIN	Epimerase domain-containing protein. (156 aa)
	F6QYI8_CIOIN	Sulfatase domain-containing protein. (244 aa)
	Ci-Net	Transcription factor protein. (205 aa)
	LOC100177133	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (520 aa)
	Tgfbeta2	TGF_BETA_2 domain-containing protein. (435 aa)
	mox	Transcription factor protein. (176 aa)
	LOC100185679	Stanniocalcin-like. (237 aa)
	LOC100180112	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1106 aa)
	F6TZG1_CIOIN	Sulfatase domain-containing protein. (492 aa)
	F6UN86_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (477 aa)
	LOC100176761	WD_REPEATS_REGION domain-containing protein. (383 aa)
	F6RR11_CIOIN	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (422 aa)
	ciatpsyna	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (554 aa)
	F6VUM2_CIOIN	Glutamine synthetase. (334 aa)
	LOC100180068	GDP-L-fucose synthase. (317 aa)
	F7AQ24_CIOIN	Uncharacterized protein. (323 aa)
	LOC104266814	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (174 aa)
	F6S6B2_CIOIN	Phosphoinositide phospholipase C. (1236 aa)
	F6TJ09_CIOIN	Sulfatase domain-containing protein. (238 aa)
	F6WUP4_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	LOC100187202	Sulfatase domain-containing protein. (515 aa)
	F6TBE2_CIOIN	Uncharacterized protein. (444 aa)
	F6Z442_CIOIN	Fibrinogen C-terminal domain-containing protein. (331 aa)
	F6VK85_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (754 aa)
	Zf(c2h2)-69	Uncharacterized protein. (940 aa)
	LOC100176958	Golgi-associated plant pathogenesis-related protein 1 isoform X1; Belongs to the CRISP family. (192 aa)
	LOC100183377	Vasohibin-1-like isoform X2. (319 aa)
	F6ZGR3_CIOIN	Uncharacterized protein. (670 aa)
	F6SGI6_CIOIN	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (734 aa)
	Tgfbr-iib	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (567 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QYI8_CIOIN	F6TJ09_CIOIN	ENSCINP00000018053	ENSCINP00000007764	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.941
F6R265_CIOIN	LOC100180068	ENSCINP00000018387	ENSCINP00000011654	Epimerase domain-containing protein.	GDP-L-fucose synthase.	0.901
F6RR11_CIOIN	F6VUM2_CIOIN	ENSCINP00000013130	ENSCINP00000012035	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Glutamine synthetase.	0.514
F6RR11_CIOIN	F7AZD3_CIOIN	ENSCINP00000013130	ENSCINP00000019213	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.666
F6RR11_CIOIN	LOC100177133	ENSCINP00000013130	ENSCINP00000017546	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.997
F6RR11_CIOIN	ciatpsyna	ENSCINP00000013130	ENSCINP00000013107	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.543
F6S6B2_CIOIN	F6UN86_CIOIN	ENSCINP00000009002	ENSCINP00000013966	Phosphoinositide phospholipase C.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.605
F6S6B2_CIOIN	F6WUP4_CIOIN	ENSCINP00000009002	ENSCINP00000007661	Phosphoinositide phospholipase C.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.401
F6T2G1_CIOIN	F6TLB6_CIOIN	ENSCINP00000029547	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.950
F6T2G1_CIOIN	F6W3W9_CIOIN	ENSCINP00000029547	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.946
F6TBE2_CIOIN	F6WXG6_CIOIN	ENSCINP00000006801	ENSCINP00000019058	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.423
F6TJ09_CIOIN	F6QYI8_CIOIN	ENSCINP00000007764	ENSCINP00000018053	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.941
F6TJ09_CIOIN	F7BEW6_CIOIN	ENSCINP00000007764	ENSCINP00000023003	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.940
F6TLB6_CIOIN	F6T2G1_CIOIN	ENSCINP00000007196	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.950
F6TLB6_CIOIN	F6W3W9_CIOIN	ENSCINP00000007196	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.949
F6UN86_CIOIN	F6S6B2_CIOIN	ENSCINP00000013966	ENSCINP00000009002	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Phosphoinositide phospholipase C.	0.605
F6UN86_CIOIN	F6WUP4_CIOIN	ENSCINP00000013966	ENSCINP00000007661	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.589
F6UN86_CIOIN	F7AQ24_CIOIN	ENSCINP00000013966	ENSCINP00000010164	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.620
F6UN86_CIOIN	H2XV03_CIOIN	ENSCINP00000013966	ENSCINP00000033487	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.503
F6UN86_CIOIN	LOC100180112	ENSCINP00000013966	ENSCINP00000014240	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.909