(57 nodes) Regulation of cell-substrate adhesion network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2Y0R5_CIOIN	Uncharacterized protein. (306 aa)
	LOC100178882	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (167 aa)
	cdc42	Uncharacterized protein. (95 aa)
	F6SBT6_CIOIN	Uncharacterized protein. (66 aa)
	Zf(c2h2)-69	Uncharacterized protein. (940 aa)
	F6UWK1_CIOIN	TFCD_C domain-containing protein. (1191 aa)
	LOC100184368	Integrin-linked protein kinase. (447 aa)
	LOC100178597	Myeloid-associated differentiation marker-like protein 2 isoform X1. (285 aa)
	LOC448957	Rac4 protein. (193 aa)
	Rac3a	Uncharacterized protein. (194 aa)
	LOC448958	Rac5 protein. (193 aa)
	LOC445702	Rac1 protein isoform X1. (192 aa)
	F6TLJ7_CIOIN	Uncharacterized protein. (895 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	F6WUP4_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
	LOC100187265	Uncharacterized protein. (949 aa)
	LOC100176196	Protein RCC2 homolog. (475 aa)
	F6S5L9_CIOIN	SH3 domain-containing protein. (774 aa)
	LOC100180068	GDP-L-fucose synthase. (317 aa)
	F6RJA6_CIOIN	Uncharacterized protein. (322 aa)
	F6RI21_CIOIN	Uncharacterized protein. (355 aa)
	F6WW63_CIOIN	Amidase domain-containing protein. (197 aa)
	F6UMA7_CIOIN	PID domain-containing protein. (458 aa)
	LOC100180438	Polymerase delta-interacting protein 2-like. (376 aa)
	F6ZRP3_CIOIN	Uncharacterized protein. (655 aa)
	LOC100176592	Ras suppressor protein 1-like isoform X2. (276 aa)
	F6R265_CIOIN	Epimerase domain-containing protein. (156 aa)
	F6YM26_CIOIN	Uncharacterized protein. (155 aa)
	F6PIT9_CIOIN	Uncharacterized protein. (210 aa)
	F6TJR3_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (242 aa)
	F6V8F4_CIOIN	Uncharacterized protein. (215 aa)
	F7AV79_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (228 aa)
	F7A9D2_CIOIN	Uncharacterized protein. (323 aa)
	Rac2	Uncharacterized protein. (192 aa)
	F6TTH0_CIOIN	Uncharacterized protein. (426 aa)
	F6V476_CIOIN	Uncharacterized protein. (282 aa)
	F6V3W8_CIOIN	Uncharacterized protein. (264 aa)
	F7B221_CIOIN	LIM domain-containing protein. (326 aa)
	rcl1	Rac and Cdc42-like 1 protein. (194 aa)
	F6ZK41_CIOIN	Kindlin_2_N domain-containing protein. (285 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	F7AK80_CIOIN	Uncharacterized protein. (382 aa)
	F7AIB9_CIOIN	Uncharacterized protein. (271 aa)
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	LOC100186675	AP-1 complex-associated regulatory protein isoform X1. (287 aa)
	H2XMX0_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (143 aa)
	H2XRB7_CIOIN	Amidase domain-containing protein. (322 aa)
	LOC100178355	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	H2XS74_CIOIN	Uncharacterized protein. (301 aa)
	H2XUL2_CIOIN	Uncharacterized protein. (299 aa)
	H2XWW8_CIOIN	Olfactomedin-like domain-containing protein. (121 aa)
	H2XYX1_CIOIN	Uncharacterized protein. (59 aa)
	H2Y0Z3_CIOIN	Rho-GAP domain-containing protein. (245 aa)
	H2Y1D3_CIOIN	Uncharacterized protein. (132 aa)
	H2Y1K9_CIOIN	Uncharacterized protein. (674 aa)
	H2Y255_CIOIN	CTCK domain-containing protein. (191 aa)
	LOC100185663	Vinculin. (1062 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PIT9_CIOIN	F6TTH0_CIOIN	ENSCINP00000020211	ENSCINP00000024081	Uncharacterized protein.	Uncharacterized protein.	0.451
F6PIT9_CIOIN	F6ZRP3_CIOIN	ENSCINP00000020211	ENSCINP00000016246	Uncharacterized protein.	Uncharacterized protein.	0.404
F6PIT9_CIOIN	F7A9D2_CIOIN	ENSCINP00000020211	ENSCINP00000023644	Uncharacterized protein.	Uncharacterized protein.	0.404
F6PIT9_CIOIN	F7AIB9_CIOIN	ENSCINP00000020211	ENSCINP00000029357	Uncharacterized protein.	Uncharacterized protein.	0.412
F6PIT9_CIOIN	H2Y1D3_CIOIN	ENSCINP00000020211	ENSCINP00000035717	Uncharacterized protein.	Uncharacterized protein.	0.451
F6R265_CIOIN	LOC100180068	ENSCINP00000018387	ENSCINP00000011654	Epimerase domain-containing protein.	GDP-L-fucose synthase.	0.901
F6S5L9_CIOIN	F6WUP4_CIOIN	ENSCINP00000011338	ENSCINP00000007661	SH3 domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.894
F6S5L9_CIOIN	H2XS74_CIOIN	ENSCINP00000011338	ENSCINP00000032508	SH3 domain-containing protein.	Uncharacterized protein.	0.771
F6S5L9_CIOIN	H2XUL2_CIOIN	ENSCINP00000011338	ENSCINP00000033346	SH3 domain-containing protein.	Uncharacterized protein.	0.771
F6S5L9_CIOIN	LOC100184368	ENSCINP00000011338	ENSCINP00000003234	SH3 domain-containing protein.	Integrin-linked protein kinase.	0.404
F6S5L9_CIOIN	LOC100185663	ENSCINP00000011338	ENSCINP00000036097	SH3 domain-containing protein.	Vinculin.	0.741
F6SBT6_CIOIN	F7B221_CIOIN	ENSCINP00000002380	ENSCINP00000024747	Uncharacterized protein.	LIM domain-containing protein.	0.581
F6SBT6_CIOIN	LOC100184368	ENSCINP00000002380	ENSCINP00000003234	Uncharacterized protein.	Integrin-linked protein kinase.	0.718
F6SBT6_CIOIN	LOC100185663	ENSCINP00000002380	ENSCINP00000036097	Uncharacterized protein.	Vinculin.	0.448
F6T2G1_CIOIN	F6TLB6_CIOIN	ENSCINP00000029547	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.950
F6T2G1_CIOIN	F6TLJ7_CIOIN	ENSCINP00000029547	ENSCINP00000007183	Uncharacterized protein.	Uncharacterized protein.	0.480
F6T2G1_CIOIN	F6W3W9_CIOIN	ENSCINP00000029547	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.946
F6TJR3_CIOIN	F7AV79_CIOIN	ENSCINP00000021779	ENSCINP00000023348	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.903
F6TJR3_CIOIN	H2XMX0_CIOIN	ENSCINP00000021779	ENSCINP00000031003	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.906
F6TJR3_CIOIN	LOC100178882	ENSCINP00000021779	ENSCINP00000000095	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.904