(63 nodes) Negative regulation of endopeptidase activity network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100182584	Low-density lipoprotein receptor-related protein 11. (387 aa)
	H2XQL2_CIOIN	Uncharacterized protein. (460 aa)
	H2XR85_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (1053 aa)
	H2XS44_CIOIN	BPTI/Kunitz inhibitor domain-containing protein. (523 aa)
	LOC100175802	Peroxiredoxin-like. (235 aa)
	H2XUQ9_CIOIN	VIT domain-containing protein. (207 aa)
	H2XVP2_CIOIN	Uncharacterized protein. (226 aa)
	Not2	SERPIN domain-containing protein; Belongs to the serpin family. (412 aa)
	H2XY37_CIOIN	Uncharacterized protein. (127 aa)
	H2XYD4_CIOIN	Uncharacterized protein. (216 aa)
	F6QUI4_CIOIN	Uncharacterized protein. (312 aa)
	F6Z6J9_CIOIN	NTR domain-containing protein. (193 aa)
	F6THB4_CIOIN	Uncharacterized protein. (181 aa)
	F7A2D4_CIOIN	BPTI/Kunitz inhibitor domain-containing protein. (271 aa)
	LOC100176561	WD_REPEATS_REGION domain-containing protein. (491 aa)
	LOC100176269	Leukocyte elastase inhibitor-like; Belongs to the serpin family. (409 aa)
	F6ZXA7_CIOIN	FAD-binding PCMH-type domain-containing protein. (524 aa)
	F6SDP7_CIOIN	EGF-like domain-containing protein. (628 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	F6ZM33_CIOIN	RING-type domain-containing protein. (330 aa)
	F6PS87_CIOIN	RING-type domain-containing protein. (713 aa)
	F7BBP3_CIOIN	Uncharacterized protein. (1493 aa)
	F6TTI3_CIOIN	Ubiquitin carboxyl-terminal hydrolase. (512 aa)
	LOC100181494	Baculoviral IAP repeat-containing protein 3. (986 aa)
	LOC100178206	Uncharacterized protein. (140 aa)
	H2Y178_CIOIN	SERPIN domain-containing protein; Belongs to the serpin family. (411 aa)
	H2Y213_CIOIN	Uncharacterized protein. (124 aa)
	c3-1	NTR domain-containing protein. (1771 aa)
	F6TJN1_CIOIN	Uncharacterized protein. (754 aa)
	F7BB43_CIOIN	Uncharacterized protein. (1264 aa)
	LOC100177185	SERPIN domain-containing protein; Belongs to the serpin family. (400 aa)
	LOC100175935	Ubiquitin carboxyl-terminal hydrolase. (328 aa)
	Zf(ring)-14	RING-type domain-containing protein. (879 aa)
	F6PW14_CIOIN	SERPIN domain-containing protein; Belongs to the serpin family. (416 aa)
	F6V1K9_CIOIN	Uncharacterized protein. (302 aa)
	LOC100182621	RING-type domain-containing protein. (672 aa)
	F6SFZ9_CIOIN	RING-type domain-containing protein. (139 aa)
	zf(ring)-24	RING-type domain-containing protein. (866 aa)
	F6PKX9_CIOIN	SERPIN domain-containing protein; Belongs to the serpin family. (147 aa)
	LOC100175630	Protein D2. (177 aa)
	F6R5K2_CIOIN	Uncharacterized protein. (316 aa)
	F6PIT9_CIOIN	Uncharacterized protein. (210 aa)
	F6XKR6_CIOIN	Uncharacterized protein. (180 aa)
	Zf(ring)-22	RING-type domain-containing protein. (262 aa)
	F6X972_CIOIN	Uncharacterized protein. (144 aa)
	F6U649_CIOIN	Uncharacterized protein. (1315 aa)
	F6U637_CIOIN	Uncharacterized protein. (689 aa)
	F7AAV2_CIOIN	EGF-like domain-containing protein. (618 aa)
	F7A9C9_CIOIN	Uncharacterized protein. (337 aa)
	LOC100179418	Leukocyte elastase inhibitor-like isoform X1; Belongs to the serpin family. (408 aa)
	F6V4V0_CIOIN	Sortilin. (1459 aa)
	LOC100181233	Delta(24)-sterol reductase-like. (513 aa)
	F6UBX1_CIOIN	VWFA domain-containing protein. (207 aa)
	F6QW56_CIOIN	Uncharacterized protein. (1026 aa)
	F7BHT5_CIOIN	SERPIN domain-containing protein; Belongs to the serpin family. (372 aa)
	F6Y6R0_CIOIN	Uncharacterized protein. (393 aa)
	LOC100179000	SERPIN domain-containing protein; Belongs to the serpin family. (375 aa)
	H2XJG5_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
	H2XMS9_CIOIN	Uncharacterized protein. (242 aa)
	H2XMU4_CIOIN	NTR domain-containing protein. (526 aa)
	H2XNV6_CIOIN	DUF3677 domain-containing protein. (2201 aa)
	LOC100175823	Cysteine-rich motor neuron 1 protein-like. (118 aa)
	H2XPE0_CIOIN	Uncharacterized protein. (202 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PIT9_CIOIN	F6PKX9_CIOIN	ENSCINP00000020211	ENSCINP00000006259	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.511
F6PIT9_CIOIN	F6PW14_CIOIN	ENSCINP00000020211	ENSCINP00000001388	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.511
F6PIT9_CIOIN	F6Z6J9_CIOIN	ENSCINP00000020211	ENSCINP00000016537	Uncharacterized protein.	NTR domain-containing protein.	0.481
F6PIT9_CIOIN	F7BHT5_CIOIN	ENSCINP00000020211	ENSCINP00000026396	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.511
F6PIT9_CIOIN	H2XVP2_CIOIN	ENSCINP00000020211	ENSCINP00000033726	Uncharacterized protein.	Uncharacterized protein.	0.481
F6PIT9_CIOIN	H2XY37_CIOIN	ENSCINP00000020211	ENSCINP00000034571	Uncharacterized protein.	Uncharacterized protein.	0.481
F6PIT9_CIOIN	LOC100177185	ENSCINP00000020211	ENSCINP00000018441	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.466
F6PIT9_CIOIN	LOC100179000	ENSCINP00000020211	ENSCINP00000029020	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.511
F6PIT9_CIOIN	Not2	ENSCINP00000020211	ENSCINP00000034368	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.457
F6PKX9_CIOIN	F6PIT9_CIOIN	ENSCINP00000006259	ENSCINP00000020211	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.511
F6PW14_CIOIN	F6PIT9_CIOIN	ENSCINP00000001388	ENSCINP00000020211	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.511
F6R5K2_CIOIN	F6SFZ9_CIOIN	ENSCINP00000020067	ENSCINP00000000466	Uncharacterized protein.	RING-type domain-containing protein.	0.900
F6R5K2_CIOIN	Zf(ring)-14	ENSCINP00000020067	ENSCINP00000000045	Uncharacterized protein.	RING-type domain-containing protein.	0.904
F6R5K2_CIOIN	Zf(ring)-22	ENSCINP00000020067	ENSCINP00000021657	Uncharacterized protein.	RING-type domain-containing protein.	0.900
F6SDP7_CIOIN	F7AAV2_CIOIN	ENSCINP00000012732	ENSCINP00000023392	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.902
F6SFZ9_CIOIN	F6R5K2_CIOIN	ENSCINP00000000466	ENSCINP00000020067	RING-type domain-containing protein.	Uncharacterized protein.	0.900
F6SFZ9_CIOIN	Zf(ring)-14	ENSCINP00000000466	ENSCINP00000000045	RING-type domain-containing protein.	RING-type domain-containing protein.	0.900
F6SFZ9_CIOIN	Zf(ring)-22	ENSCINP00000000466	ENSCINP00000021657	RING-type domain-containing protein.	RING-type domain-containing protein.	0.900
F6TTI3_CIOIN	LOC100175935	ENSCINP00000008849	ENSCINP00000001676	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin carboxyl-terminal hydrolase.	0.724
F6UBX1_CIOIN	H2XUQ9_CIOIN	ENSCINP00000024966	ENSCINP00000033393	VWFA domain-containing protein.	VIT domain-containing protein.	0.936