(13 nodes) Cholesterol binding network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F7A5Y1_CIOIN	Uncharacterized protein. (532 aa)
	H2Y342_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (228 aa)
	H2XWW3_CIOIN	Uncharacterized protein. (223 aa)
	H2XMP3_CIOIN	ML domain-containing protein. (152 aa)
	H2XJI5_CIOIN	Uncharacterized protein. (321 aa)
	F6TKD8_CIOIN	ML domain-containing protein. (150 aa)
	F6RCK1_CIOIN	SSD domain-containing protein. (1339 aa)
	F6Z7W1_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (697 aa)
	F6SFB8_CIOIN	Uncharacterized protein. (493 aa)
	F6TFC4_CIOIN	LRRNT domain-containing protein. (542 aa)
	F6YGU8_CIOIN	SSD domain-containing protein. (1275 aa)
	LOC100176028	Erlin-1. (333 aa)
	F6W8D0_CIOIN	Oxysterol-binding protein; Belongs to the OSBP family. (951 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6RCK1_CIOIN	F6TKD8_CIOIN	ENSCINP00000018303	ENSCINP00000021760	SSD domain-containing protein.	ML domain-containing protein.	0.774
F6RCK1_CIOIN	H2XMP3_CIOIN	ENSCINP00000018303	ENSCINP00000030926	SSD domain-containing protein.	ML domain-containing protein.	0.774
F6SFB8_CIOIN	F7A5Y1_CIOIN	ENSCINP00000012457	ENSCINP00000018917	Uncharacterized protein.	Uncharacterized protein.	0.478
F6TKD8_CIOIN	F6RCK1_CIOIN	ENSCINP00000021760	ENSCINP00000018303	ML domain-containing protein.	SSD domain-containing protein.	0.774
F6TKD8_CIOIN	F6YGU8_CIOIN	ENSCINP00000021760	ENSCINP00000008700	ML domain-containing protein.	SSD domain-containing protein.	0.774
F6YGU8_CIOIN	F6TKD8_CIOIN	ENSCINP00000008700	ENSCINP00000021760	SSD domain-containing protein.	ML domain-containing protein.	0.774
F6YGU8_CIOIN	H2XMP3_CIOIN	ENSCINP00000008700	ENSCINP00000030926	SSD domain-containing protein.	ML domain-containing protein.	0.976
F7A5Y1_CIOIN	F6SFB8_CIOIN	ENSCINP00000018917	ENSCINP00000012457	Uncharacterized protein.	Uncharacterized protein.	0.478
H2XMP3_CIOIN	F6RCK1_CIOIN	ENSCINP00000030926	ENSCINP00000018303	ML domain-containing protein.	SSD domain-containing protein.	0.774
H2XMP3_CIOIN	F6YGU8_CIOIN	ENSCINP00000030926	ENSCINP00000008700	ML domain-containing protein.	SSD domain-containing protein.	0.976