(16 nodes) Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	LOC100182410	Dihydrofolate reductase-like; Belongs to the dihydrofolate reductase family. (194 aa)
	H2XLB1_CIOIN	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (188 aa)
	F6WG12_CIOIN	Uncharacterized protein. (202 aa)
	LOC100175137	Dihydropteridine reductase isoform X2. (234 aa)
	F6ZU97_CIOIN	Uncharacterized protein. (460 aa)
	F6WNP9_CIOIN	NAD(P)-bd_dom domain-containing protein. (222 aa)
	LOC100184767	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (921 aa)
	F6T3G6_CIOIN	Uncharacterized protein. (310 aa)
	LOC100182702	F420_oxidored domain-containing protein. (364 aa)
	F6X034_CIOIN	Uncharacterized protein. (290 aa)
	LOC100185664	C-1-tetrahydrofolate synthase, cytoplasmic-like. (934 aa)
	F6W1X7_CIOIN	Uncharacterized protein. (299 aa)
	LOC100187490	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (270 aa)
	LOC100180174	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (650 aa)
	LOC100183100	Uncharacterized protein LOC100183100. (202 aa)
	H2XXG5_CIOIN	AlaDh_PNT_N domain-containing protein. (215 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6W1X7_CIOIN	F6X034_CIOIN	ENSCINP00000006770	ENSCINP00000005743	Uncharacterized protein.	Uncharacterized protein.	0.436
F6W1X7_CIOIN	LOC100187490	ENSCINP00000006770	ENSCINP00000011143	Uncharacterized protein.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.945
F6X034_CIOIN	F6W1X7_CIOIN	ENSCINP00000005743	ENSCINP00000006770	Uncharacterized protein.	Uncharacterized protein.	0.436
F6X034_CIOIN	H2XLB1_CIOIN	ENSCINP00000005743	ENSCINP00000030443	Uncharacterized protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.578
F6X034_CIOIN	LOC100180174	ENSCINP00000005743	ENSCINP00000013160	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.991
F6X034_CIOIN	LOC100182410	ENSCINP00000005743	ENSCINP00000031349	Uncharacterized protein.	Dihydrofolate reductase-like; Belongs to the dihydrofolate reductase family.	0.578
F6X034_CIOIN	LOC100182702	ENSCINP00000005743	ENSCINP00000002783	Uncharacterized protein.	F420_oxidored domain-containing protein.	0.436
F6X034_CIOIN	LOC100184767	ENSCINP00000005743	ENSCINP00000016529	Uncharacterized protein.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.940
F6X034_CIOIN	LOC100185664	ENSCINP00000005743	ENSCINP00000006018	Uncharacterized protein.	C-1-tetrahydrofolate synthase, cytoplasmic-like.	0.993
F6X034_CIOIN	LOC100187490	ENSCINP00000005743	ENSCINP00000011143	Uncharacterized protein.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.436
F6ZU97_CIOIN	H2XXG5_CIOIN	ENSCINP00000019576	ENSCINP00000034349	Uncharacterized protein.	AlaDh_PNT_N domain-containing protein.	0.949
H2XLB1_CIOIN	F6X034_CIOIN	ENSCINP00000030443	ENSCINP00000005743	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.578
H2XLB1_CIOIN	LOC100175137	ENSCINP00000030443	ENSCINP00000019999	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Dihydropteridine reductase isoform X2.	0.401
H2XLB1_CIOIN	LOC100180174	ENSCINP00000030443	ENSCINP00000013160	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.474
H2XLB1_CIOIN	LOC100185664	ENSCINP00000030443	ENSCINP00000006018	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	C-1-tetrahydrofolate synthase, cytoplasmic-like.	0.652
H2XXG5_CIOIN	F6ZU97_CIOIN	ENSCINP00000034349	ENSCINP00000019576	AlaDh_PNT_N domain-containing protein.	Uncharacterized protein.	0.949
LOC100175137	H2XLB1_CIOIN	ENSCINP00000019999	ENSCINP00000030443	Dihydropteridine reductase isoform X2.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.401
LOC100175137	LOC100182410	ENSCINP00000019999	ENSCINP00000031349	Dihydropteridine reductase isoform X2.	Dihydrofolate reductase-like; Belongs to the dihydrofolate reductase family.	0.937
LOC100180174	F6X034_CIOIN	ENSCINP00000013160	ENSCINP00000005743	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.991
LOC100180174	H2XLB1_CIOIN	ENSCINP00000013160	ENSCINP00000030443	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.474