(165 nodes) Phosphatase activity network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100181041	Myotubularin-related protein 9 isoform X1. (562 aa)
	LOC100180111	Uncharacterized protein. (263 aa)
	ciap	Alkaline phosphatase. (579 aa)
	F6Q7P2_CIOIN	Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (312 aa)
	LOC100178593	CTD nuclear envelope phosphatase 1A-like. (257 aa)
	F6Q5E4_CIOIN	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	F7AGL2_CIOIN	Uncharacterized protein. (310 aa)
	F6ZD22_CIOIN	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (265 aa)
	LOC100175699	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (602 aa)
	LOC100186065	Uncharacterized protein. (450 aa)
	LOC100180551	Inositol-1-monophosphatase. (275 aa)
	LOC100182434	Uncharacterized protein. (403 aa)
	H2Y3P6_CIOIN	Rho-GAP domain-containing protein. (708 aa)
	H2Y3N0_CIOIN	UBA domain-containing protein. (90 aa)
	H2Y3J2_CIOIN	Uncharacterized protein. (238 aa)
	H2Y377_CIOIN	SAC domain-containing protein. (147 aa)
	LOC100185018	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (411 aa)
	H2Y1X2_CIOIN	Uncharacterized protein. (150 aa)
	H2Y1W0_CIOIN	Myotubularin phosphatase domain-containing protein. (374 aa)
	H2Y1V3_CIOIN	Tyrosine-protein phosphatase domain-containing protein. (227 aa)
	H2Y1M2_CIOIN	Uncharacterized protein. (407 aa)
	LOC100185112	Phospholipid phosphatase 6-like. (210 aa)
	H2XZV1_CIOIN	Uncharacterized protein. (241 aa)
	LOC100176672	Tyrosine-protein phosphatase domain-containing protein. (270 aa)
	LOC100177641	Uncharacterized protein. (226 aa)
	LOC100181442	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (422 aa)
	H2XXN7_CIOIN	Uncharacterized protein. (721 aa)
	H2XX55_CIOIN	Uncharacterized protein. (233 aa)
	H2XWL5_CIOIN	Metallophos domain-containing protein. (176 aa)
	LOC100177985	Phospholipid phosphatase 1 isoform X1. (303 aa)
	H2XW92_CIOIN	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (229 aa)
	H2XVA3_CIOIN	Myotubularin phosphatase domain-containing protein. (430 aa)
	H2XV34_CIOIN	Uncharacterized protein. (117 aa)
	H2XV03_CIOIN	Uncharacterized protein. (625 aa)
	H2XUU1_CIOIN	Uncharacterized protein. (101 aa)
	H2XUG6_CIOIN	Uncharacterized protein. (250 aa)
	H2XU80_CIOIN	FERM domain-containing protein. (235 aa)
	H2XU15_CIOIN	TYR_PHOSPHATASE_2 domain-containing protein. (185 aa)
	H2XU06_CIOIN	Uncharacterized protein. (177 aa)
	H2XTQ4_CIOIN	FCP1 homology domain-containing protein. (119 aa)
	H2XSN9_CIOIN	Uncharacterized protein. (242 aa)
	H2XRY3_CIOIN	Uncharacterized protein. (183 aa)
	H2XQU6_CIOIN	Metallophos domain-containing protein. (290 aa)
	H2XQT4_CIOIN	Uncharacterized protein. (321 aa)
	H2XQI8_CIOIN	DUF1866 domain-containing protein. (194 aa)
	LOC100176917	Alkaline phosphatase. (562 aa)
	H2XPV1_CIOIN	Uncharacterized protein. (584 aa)
	LOC100184095	Low molecular weight phosphotyrosine protein phosphatase 1-like. (100 aa)
	H2XPH8_CIOIN	Metallophos domain-containing protein. (237 aa)
	LOC100185994	PPM-type phosphatase domain-containing protein. (377 aa)
	H2XNN7_CIOIN	Uncharacterized protein. (112 aa)
	LOC100185744	Protein tyrosine phosphatase type IVA 3. (172 aa)
	H2XMJ7_CIOIN	IPPc domain-containing protein. (430 aa)
	LOC104265547	Uncharacterized protein LOC104265547 isoform X1. (119 aa)
	H2XLZ9_CIOIN	Uncharacterized protein. (644 aa)
	LOC100177056	Uncharacterized protein. (576 aa)
	H2XLI5_CIOIN	Serine/threonine-protein phosphatase. (305 aa)
	H2XL49_CIOIN	Uncharacterized protein. (234 aa)
	LOC100177460	Serine/threonine-protein phosphatase. (305 aa)
	H2XK17_CIOIN	Uncharacterized protein. (337 aa)
	H2XJI0_CIOIN	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (149 aa)
	H2XJH7_CIOIN	Uncharacterized protein. (687 aa)
	F6X0L7_CIOIN	FHA_2 domain-containing protein. (571 aa)
	LOC100176740	Uncharacterized protein. (325 aa)
	F6R0H1_CIOIN	Uncharacterized protein. (188 aa)
	F6PJS6_CIOIN	AB hydrolase-1 domain-containing protein. (414 aa)
	F6Z630_CIOIN	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (379 aa)
	F6YPN5_CIOIN	Tyrosine-protein phosphatase domain-containing protein. (204 aa)
	F6X4K3_CIOIN	Uncharacterized protein. (260 aa)
	F6X4N7_CIOIN	Serine/threonine-protein phosphatase. (324 aa)
	F7AP73_CIOIN	Uncharacterized protein. (354 aa)
	LOC100179989	PPM-type phosphatase domain-containing protein. (490 aa)
	F6WVN4_CIOIN	acidPPc domain-containing protein. (302 aa)
	LOC100178245	Uncharacterized protein. (243 aa)
	LOC100178124	Inositol monophosphatase 3-like. (324 aa)
	F6XA93_CIOIN	Uncharacterized protein. (1663 aa)
	LOC100182013	Fibronectin isoform X1. (653 aa)
	F6PWD4_CIOIN	SH3 domain-containing protein. (595 aa)
	F6UCL8_CIOIN	Uncharacterized protein. (223 aa)
	F6UCM8_CIOIN	Uncharacterized protein. (445 aa)
	LOC100184820	Uncharacterized protein LOC100184820. (227 aa)
	LOC100178594	Fructose-2,6-bisphosphatase TIGAR-like. (261 aa)
	LOC100184050	Serine/threonine/tyrosine-interacting-like protein 1. (296 aa)
	LOC100184506	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (388 aa)
	F6YWY7_CIOIN	6PF2K domain-containing protein. (448 aa)
	F6YWZ8_CIOIN	TYR_PHOSPHATASE_2 domain-containing protein. (327 aa)
	F6SGF7_CIOIN	Uncharacterized protein. (320 aa)
	F6PT06_CIOIN	Uncharacterized protein. (183 aa)
	F6PTJ9_CIOIN	PPM-type phosphatase domain-containing protein. (526 aa)
	Dusp1.2.4.5	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (434 aa)
	LOC100187300	Leucine-rich repeat and IQ domain-containing protein 4-like isoform X3. (605 aa)
	F6Y5T9_CIOIN	SH2 domain-containing protein. (463 aa)
	F6ZLD5_CIOIN	Protein kinase domain-containing protein. (164 aa)
	F7A4P8_CIOIN	Uncharacterized protein. (383 aa)
	LOC100176080	Prostatic acid phosphatase-like; Belongs to the histidine acid phosphatase family. (435 aa)
	Vsp	Uncharacterized protein. (570 aa)
	F7AX37_CIOIN	LNS2 domain-containing protein. (935 aa)
	F6Y940_CIOIN	Serine/threonine-protein phosphatase. (241 aa)
	F6WY52_CIOIN	Uncharacterized protein. (485 aa)
	F6YM31_CIOIN	TYR_PHOSPHATASE_2 domain-containing protein. (348 aa)
	F7AD14_CIOIN	Uncharacterized protein. (118 aa)
	F6WWW9_CIOIN	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (288 aa)
	F6YSM6_CIOIN	DUF89 domain-containing protein. (439 aa)
	Dusp6.9	Uncharacterized protein. (499 aa)
	F6ZMG2_CIOIN	Uncharacterized protein. (433 aa)
	F6PKT6_CIOIN	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (822 aa)
	F6QX49_CIOIN	Tartrate-resistant acid phosphatase type 5. (330 aa)
	F6UD40_CIOIN	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (434 aa)
	LOC100181998	Uncharacterized protein. (519 aa)
	F6PP55_CIOIN	Uncharacterized protein. (445 aa)
	LOC100183363	Protein phosphatase 1A-like isoform X2. (412 aa)
	LOC100182691	SAC domain-containing protein. (590 aa)
	F6W4M3_CIOIN	Uncharacterized protein. (270 aa)
	LOC100182135	Uncharacterized protein. (180 aa)
	F6WRK0_CIOIN	Protein phosphatase; Belongs to the PP2C family. (328 aa)
	F6TGU6_CIOIN	Uncharacterized protein. (420 aa)
	F6XU54_CIOIN	Metallophos domain-containing protein. (252 aa)
	F7AM82_CIOIN	Uncharacterized protein. (212 aa)
	LOC100178482	Uncharacterized protein. (180 aa)
	LOC100177439	Serine/threonine/tyrosine-interacting protein-like. (218 aa)
	F6UJI9_CIOIN	Uncharacterized protein. (487 aa)
	F6UJL9_CIOIN	Tartrate-resistant acid phosphatase type 5. (345 aa)
	F6YII9_CIOIN	Uncharacterized protein. (1911 aa)
	LOC100183021	Cytosolic purine 5'-nucleotidase isoform X4. (548 aa)
	LOC100182371	Uncharacterized protein. (609 aa)
	F6SUV6_CIOIN	Myotubularin phosphatase domain-containing protein. (223 aa)
	F6UVC2_CIOIN	Uncharacterized protein. (898 aa)
	LOC100183669	Protein phosphatase 1D isoform X1. (515 aa)
	F6W9J4_CIOIN	Uncharacterized protein; Belongs to the alkaline phosphatase family. (315 aa)
	F6W9Y0_CIOIN	Uncharacterized protein; Belongs to the alkaline phosphatase family. (509 aa)
	F7AFK8_CIOIN	FCP1 homology domain-containing protein. (293 aa)
	F6U0P5_CIOIN	Uncharacterized protein; Belongs to the alkaline phosphatase family. (499 aa)
	F6QL68_CIOIN	Uncharacterized protein. (318 aa)
	LOC100179541	HD domain-containing protein 2-like isoform X1. (193 aa)
	LOC100180903	2-phosphoxylose phosphatase 1 isoform X1; Belongs to the histidine acid phosphatase family. (490 aa)
	F6ZZD9_CIOIN	Uncharacterized protein. (205 aa)
	F6ZZK5_CIOIN	Alkaline phosphatase. (202 aa)
	LOC100185509	Cytosolic 5'-nucleotidase 1A. (361 aa)
	F6VI59_CIOIN	SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
	F6YQ60_CIOIN	SAC domain-containing protein. (706 aa)
	ci-cmub116	Radial spoke protein CMUB116. (765 aa)
	F7AQ24_CIOIN	Uncharacterized protein. (323 aa)
	LOC100178929	Serine/threonine-protein phosphatase. (307 aa)
	LOC100181128	PPM-type phosphatase domain-containing protein. (301 aa)
	F7B490_CIOIN	MAM domain-containing protein. (213 aa)
	F7AJJ9_CIOIN	Uncharacterized protein. (1191 aa)
	F6XNX3_CIOIN	Uncharacterized protein. (428 aa)
	F6XMR8_CIOIN	Uncharacterized protein. (638 aa)
	F6TMW1_CIOIN	TYR_PHOSPHATASE_2 domain-containing protein. (183 aa)
	LOC100183243	DHHA2 domain-containing protein. (378 aa)
	F6QJI6_CIOIN	Uncharacterized protein. (244 aa)
	F7AQ31_CIOIN	Uncharacterized protein. (429 aa)
	LOC100183137	Uncharacterized protein. (306 aa)
	F6XIK7_CIOIN	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (599 aa)
	F6WV27_CIOIN	acidPPc domain-containing protein. (405 aa)
	LOC100182088	Probable rhodanese domain-containing dual specificity protein phosphatase isoform X1. (373 aa)
	F6SPI7_CIOIN	Uncharacterized protein. (573 aa)
	F6TYR4_CIOIN	Uncharacterized protein. (759 aa)
	LOC100178587	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	LOC100178049	Probable protein phosphatase 2C T23F11.1. (327 aa)
	LOC100187321	RNA polymerase II subunit A C-terminal domain phosphatase SSU72. (192 aa)
	mech2	Mech2 protein. (360 aa)
	Ptp	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (987 aa)
	F7BP82_CIOIN	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (387 aa)
	LOC100186064	Serine/threonine-protein phosphatase. (314 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dusp6.9	Ptp	ENSCINP00000018971	ENSCINP00000008730	Uncharacterized protein.	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.427
F6PJS6_CIOIN	LOC100178245	ENSCINP00000028721	ENSCINP00000026491	AB hydrolase-1 domain-containing protein.	Uncharacterized protein.	0.707
F6PJS6_CIOIN	LOC100180551	ENSCINP00000028721	ENSCINP00000002314	AB hydrolase-1 domain-containing protein.	Inositol-1-monophosphatase.	0.687
F6PKT6_CIOIN	F6SGF7_CIOIN	ENSCINP00000018238	ENSCINP00000024400	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein.	0.651
F6PKT6_CIOIN	F7AFK8_CIOIN	ENSCINP00000018238	ENSCINP00000014062	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	FCP1 homology domain-containing protein.	0.537
F6PKT6_CIOIN	LOC100178245	ENSCINP00000018238	ENSCINP00000026491	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein.	0.527
F6PKT6_CIOIN	LOC100187321	ENSCINP00000018238	ENSCINP00000009069	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	RNA polymerase II subunit A C-terminal domain phosphatase SSU72.	0.660
F6PT06_CIOIN	F6XIK7_CIOIN	ENSCINP00000023892	ENSCINP00000007616	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.419
F6PT06_CIOIN	F6ZD22_CIOIN	ENSCINP00000023892	ENSCINP00000002133	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.900
F6PT06_CIOIN	H2XQI8_CIOIN	ENSCINP00000023892	ENSCINP00000031922	Uncharacterized protein.	DUF1866 domain-containing protein.	0.937
F6PT06_CIOIN	H2Y1X2_CIOIN	ENSCINP00000023892	ENSCINP00000035907	Uncharacterized protein.	Uncharacterized protein.	0.899
F6PT06_CIOIN	H2Y3P6_CIOIN	ENSCINP00000023892	ENSCINP00000036531	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.910
F6PT06_CIOIN	LOC100178482	ENSCINP00000023892	ENSCINP00000015459	Uncharacterized protein.	Uncharacterized protein.	0.473
F6PT06_CIOIN	LOC100182434	ENSCINP00000023892	ENSCINP00000004848	Uncharacterized protein.	Uncharacterized protein.	0.913
F6PT06_CIOIN	LOC100182691	ENSCINP00000023892	ENSCINP00000016590	Uncharacterized protein.	SAC domain-containing protein.	0.921
F6PTJ9_CIOIN	LOC100178929	ENSCINP00000023878	ENSCINP00000010125	PPM-type phosphatase domain-containing protein.	Serine/threonine-protein phosphatase.	0.429
F6PWD4_CIOIN	F6X4K3_CIOIN	ENSCINP00000025325	ENSCINP00000027927	SH3 domain-containing protein.	Uncharacterized protein.	0.584
F6PWD4_CIOIN	LOC100178594	ENSCINP00000025325	ENSCINP00000024844	SH3 domain-containing protein.	Fructose-2,6-bisphosphatase TIGAR-like.	0.586
F6Q5E4_CIOIN	F6VI59_CIOIN	ENSCINP00000001310	ENSCINP00000011235	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	SER_THR_PHOSPHATASE domain-containing protein.	0.553
F6Q5E4_CIOIN	H2XJI0_CIOIN	ENSCINP00000001310	ENSCINP00000029812	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.900