(31 nodes) Peptidyl-threonine phosphorylation network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tgfbr-iib	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (567 aa)
	F6VK85_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (754 aa)
	gsk	Glycogen synthase kinase Alpha/beta. (407 aa)
	F6R6F3_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1324 aa)
	LOC100176859	Uncharacterized protein LOC100176859. (532 aa)
	nemo-like	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (403 aa)
	F6SED5_CIOIN	Uncharacterized protein. (211 aa)
	F6V299_CIOIN	Protein kinase domain-containing protein. (523 aa)
	F6RS66_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
	LOC100181289	Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	F6WVT9_CIOIN	Protein kinase domain-containing protein. (505 aa)
	F6YIR9_CIOIN	LisH domain-containing protein. (1416 aa)
	F6T718_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (440 aa)
	F6XT42_CIOIN	Protein kinase domain-containing protein. (577 aa)
	F6Z8G0_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (454 aa)
	F6QZH0_CIOIN	Protein kinase domain-containing protein. (459 aa)
	LOC100175606	Homeodomain-interacting protein kinase 2. (1082 aa)
	ck2a	Casein kinase 2 alpha subunit; Belongs to the protein kinase superfamily. (385 aa)
	F6ZLD5_CIOIN	Protein kinase domain-containing protein. (164 aa)
	F7A9P4_CIOIN	NUC194 domain-containing protein. (726 aa)
	F6SBN1_CIOIN	Protein kinase domain-containing protein. (140 aa)
	H2XLY5_CIOIN	DMPK_coil domain-containing protein. (189 aa)
	H2XM17_CIOIN	FAT domain-containing protein. (187 aa)
	H2XRL6_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (209 aa)
	H2XSQ7_CIOIN	CRIB domain-containing protein. (160 aa)
	H2XVI5_CIOIN	AGC-kinase C-terminal domain-containing protein. (240 aa)
	H2XWT8_CIOIN	Uncharacterized protein. (206 aa)
	H2XY43_CIOIN	Uncharacterized protein. (388 aa)
	H2Y066_CIOIN	Uncharacterized protein. (361 aa)
	H2Y3C6_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (540 aa)
	H2Y3M4_CIOIN	Uncharacterized protein. (185 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QZH0_CIOIN	H2XLY5_CIOIN	ENSCINP00000016849	ENSCINP00000030667	Protein kinase domain-containing protein.	DMPK_coil domain-containing protein.	0.862
F6QZH0_CIOIN	H2XY43_CIOIN	ENSCINP00000016849	ENSCINP00000034577	Protein kinase domain-containing protein.	Uncharacterized protein.	0.888
F6T718_CIOIN	F6YIR9_CIOIN	ENSCINP00000015725	ENSCINP00000015316	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	LisH domain-containing protein.	0.430
F6VK85_CIOIN	F7A9P4_CIOIN	ENSCINP00000002868	ENSCINP00000023638	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	NUC194 domain-containing protein.	0.699
F6VK85_CIOIN	H2XM17_CIOIN	ENSCINP00000002868	ENSCINP00000030699	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	FAT domain-containing protein.	0.943
F6VK85_CIOIN	H2XWT8_CIOIN	ENSCINP00000002868	ENSCINP00000034122	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.925
F6VK85_CIOIN	H2Y066_CIOIN	ENSCINP00000002868	ENSCINP00000035300	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.929
F6WVT9_CIOIN	H2XLY5_CIOIN	ENSCINP00000014529	ENSCINP00000030667	Protein kinase domain-containing protein.	DMPK_coil domain-containing protein.	0.725
F6WVT9_CIOIN	H2XY43_CIOIN	ENSCINP00000014529	ENSCINP00000034577	Protein kinase domain-containing protein.	Uncharacterized protein.	0.667
F6YIR9_CIOIN	F6T718_CIOIN	ENSCINP00000015316	ENSCINP00000015725	LisH domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.430
F7A9P4_CIOIN	F6VK85_CIOIN	ENSCINP00000023638	ENSCINP00000002868	NUC194 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.699
F7A9P4_CIOIN	H2Y3C6_CIOIN	ENSCINP00000023638	ENSCINP00000036411	NUC194 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.945
F7A9P4_CIOIN	H2Y3M4_CIOIN	ENSCINP00000023638	ENSCINP00000036509	NUC194 domain-containing protein.	Uncharacterized protein.	0.900
H2XLY5_CIOIN	F6QZH0_CIOIN	ENSCINP00000030667	ENSCINP00000016849	DMPK_coil domain-containing protein.	Protein kinase domain-containing protein.	0.862
H2XLY5_CIOIN	F6WVT9_CIOIN	ENSCINP00000030667	ENSCINP00000014529	DMPK_coil domain-containing protein.	Protein kinase domain-containing protein.	0.725
H2XLY5_CIOIN	H2XVI5_CIOIN	ENSCINP00000030667	ENSCINP00000033669	DMPK_coil domain-containing protein.	AGC-kinase C-terminal domain-containing protein.	0.920
H2XLY5_CIOIN	H2XY43_CIOIN	ENSCINP00000030667	ENSCINP00000034577	DMPK_coil domain-containing protein.	Uncharacterized protein.	0.925
H2XM17_CIOIN	F6VK85_CIOIN	ENSCINP00000030699	ENSCINP00000002868	FAT domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.943
H2XM17_CIOIN	H2XWT8_CIOIN	ENSCINP00000030699	ENSCINP00000034122	FAT domain-containing protein.	Uncharacterized protein.	0.920
H2XM17_CIOIN	H2Y066_CIOIN	ENSCINP00000030699	ENSCINP00000035300	FAT domain-containing protein.	Uncharacterized protein.	0.964