(9 nodes) Hexose biosynthetic process network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	F7AZD3_CIOIN	Glucose-6-phosphate isomerase; Belongs to the GPI family. (232 aa)
	LOC100178529	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily. (345 aa)
	F6XRP8_CIOIN	MFS domain-containing protein. (445 aa)
	LOC100181512	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1186 aa)
	LOC100183090	Triosephosphate isomerase. (247 aa)
	LOC100177066	Uncharacterized protein. (641 aa)
	atf3	Transcription factor protein isoform X1. (273 aa)
	LOC100184593	Sorbitol dehydrogenase. (360 aa)
	LOC100182231	Phosphoglycerate kinase. (416 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F7AZD3_CIOIN	LOC100177066	ENSCINP00000019213	ENSCINP00000012511	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Uncharacterized protein.	0.656
F7AZD3_CIOIN	LOC100178529	ENSCINP00000019213	ENSCINP00000017905	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	0.773
F7AZD3_CIOIN	LOC100181512	ENSCINP00000019213	ENSCINP00000015426	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.662
F7AZD3_CIOIN	LOC100182231	ENSCINP00000019213	ENSCINP00000004580	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Phosphoglycerate kinase.	0.980
F7AZD3_CIOIN	LOC100183090	ENSCINP00000019213	ENSCINP00000013486	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Triosephosphate isomerase.	0.996
LOC100177066	F7AZD3_CIOIN	ENSCINP00000012511	ENSCINP00000019213	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.656
LOC100177066	LOC100178529	ENSCINP00000012511	ENSCINP00000017905	Uncharacterized protein.	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	0.960
LOC100177066	LOC100181512	ENSCINP00000012511	ENSCINP00000015426	Uncharacterized protein.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.965
LOC100177066	LOC100182231	ENSCINP00000012511	ENSCINP00000004580	Uncharacterized protein.	Phosphoglycerate kinase.	0.474
LOC100177066	LOC100183090	ENSCINP00000012511	ENSCINP00000013486	Uncharacterized protein.	Triosephosphate isomerase.	0.623
LOC100178529	F7AZD3_CIOIN	ENSCINP00000017905	ENSCINP00000019213	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.773
LOC100178529	LOC100177066	ENSCINP00000017905	ENSCINP00000012511	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	Uncharacterized protein.	0.960
LOC100178529	LOC100181512	ENSCINP00000017905	ENSCINP00000015426	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.982
LOC100178529	LOC100182231	ENSCINP00000017905	ENSCINP00000004580	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	Phosphoglycerate kinase.	0.657
LOC100178529	LOC100183090	ENSCINP00000017905	ENSCINP00000013486	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	Triosephosphate isomerase.	0.760
LOC100181512	F7AZD3_CIOIN	ENSCINP00000015426	ENSCINP00000019213	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.662
LOC100181512	LOC100177066	ENSCINP00000015426	ENSCINP00000012511	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Uncharacterized protein.	0.965
LOC100181512	LOC100178529	ENSCINP00000015426	ENSCINP00000017905	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.	0.982
LOC100181512	LOC100182231	ENSCINP00000015426	ENSCINP00000004580	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Phosphoglycerate kinase.	0.533
LOC100181512	LOC100183090	ENSCINP00000015426	ENSCINP00000013486	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Triosephosphate isomerase.	0.650